Claudia is joined by Caroline Williams to learn about the cutting-edge science of interoception – that’s how the brain interprets signals that come from inside our body. We find out how honing this skill can sometimes be helpful and why at other times it can have a negative impact on us.

Tuberculosis remains one of the deadliest infectious diseases worldwide but in Malawi a stage 3 trial is under way to develop a new vaccine. Our reporter Carrim Mpaweni checks-in on the trial’s progress.

Also on the show, Claudia speaks to psychotherapist Sophie Scott about how to persuade a loved one to get professional help when they don't want to.

Presenter: Claudia Hammond