For this Hot Topics episode, Dr. Eduardo Fernandez sits down with Dr. Thomas Beach to discuss the advances and challenges ahead in tissue biomarkers for Parkinson's disease, including colon, salivary gland and skin biopsies.

Dr. Esther Cubo joins Dr. Sarah Lidstone and the MDS Podcast to discuss her recent work on the Spanish validation of the MDS Non-Motor Rating Scale. Together to go over the reasoning for this study, the extensive process of validating this scale and what benefits it will provide to Spanish speaking populations.

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MDS Non-motor Rating Scale

The Global Parkinson's Genetics Program (GP2) is a project designed to understand the architecture of Parkinson's disease (PD). Dr. Sarah Camargos sits down with Dr. Andrew Singleton to discuss GP2 and its initiative to increase our global understanding of PD and in doing so, better understand the genetic landscape of underrepresented populations.

Laryngeal dystonia (LD) is a rare disorder affecting the vocal cords. Dr. Sarah Camargos sits down with Prof. Kristina Simonyan while she breaks down the methodology and findings of her comprehensive study investigating the temporal-spatial signature of LD.

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Dr. Sara Schaefer speaks with Dr. Beatrice Heim, author of the MDCP Review Article of the Year 2023, about alpha-synuclein seed amplification assays of the CSF and their use in the diagnosis of synucleinopathies.

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Dr. Poewe and Dr. Mahlknecht discuss the details of their Review Article of the Year on what we know about how DBS in Parkinson's disease alters symptoms, disability, survival, and more in this special episode.

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Dr. Eduardo Fernandez interviews Professor Günther Deuschl and Dr. Robin Wolke on their recent MDCP article on the challenges levodopa poses when predicting the outcome of subthalamic deep brain stimulation.

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What innovations in dystonia treatments do we have to look forward to? Dr. Mark Edwards sits down with Dr. Sarah Camargos to answer that vary question.

Why is Parkinson's disease heterogeneity important to research. Dr. Connie Marras met with Dr. Eduardo Fernandez to discuss why understanding the heterogeneity of this disease may help with prevention.

Multiple system atrophy (MSA) research has its challenges, nonetheless the field is still moving at a rapid pace. Dr. Eduardo Fernandez discusses the MDS Congress highlights for MSA with Dr. Alessandra Fanciulli.