Discover Dr. Austin Perlmutter’s insights on neuroinflammation, decision-making, and how lifestyle inputs reshape brain health and longevity.

Dr. Austin Perlmutter explains how chronic inflammation inside the brain shapes mood, cognition, and the everyday decisions that determine our long-term health. He breaks down the roles of the gut, stress, food choices, microglial activation, and disrupted sleep—revealing how these factors create “stuckness” in our thoughts and behaviors. Austin offers practical, science-backed steps to improve sleep, reduce stress inputs, enhance neural plasticity, and reprogram the brain toward healthier choices and longevity.

Dr. Austin Perlmutter is a board-certified internal medicine physician, a New York Times Bestselling Author, and a researcher. He received his medical degree from the University of Miami and completed his internal medicine residency at Oregon Health and Science University. His focus is on helping identify and resolve the biological basis for “stuckness” in the body and brain using lifestyle interventions, and he lectures internationally on this subject. He hosts the Get The STUCK OUT podcast and is a co-producer of the Alzheimer’s, the Science of Prevention Docu-series. His work on immune-mediated depression can be found in the peer-reviewed medical literature. His writing is featured online on MedPage Today, Doximity, KevinMD, Medium, Psychology Today, and MindBodyGreen. He currently serves as the Senior Director of Science and Clinical Innovation at Big Bold Health.