Never Been Sicker

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What happens when you've tried nearly 200 treatments and you're STILL struggling with chronic illness?

For Brad Pitzele, the journey started with autoimmune arthritis, followed by a melanoma diagnosis and years of searching for answers. Eventually, he was diagnosed with Lyme disease and Bartonella, leading him down a path of researching mitochondrial health, oxygen delivery, and alternative approaches to recovery.

In this episode of Never Been Sicker, Michael Rubino sits down with Brad, founder of 1000 Roads, to discuss his experience navigating chronic illness and what he learned along the way.
Brad shares how his engineering background helped him approach health challenges differently, why he believes oxygen delivery deserves more attention, and how he discovered exercise with oxygen therapy (EWOT).

They also explore the connections between environmental exposures, inflammation, chronic fatigue, brain fog, and mitochondrial function.

🎙️ Subscribe to Never Been Sicker for more conversations about environmental health, indoor air quality, and creating healthier lives.

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CHAPTERS:
00:00 Meet Brad Pitzele
00:23 Autoimmune Arthritis, Melanoma & Lyme Disease
01:57 The Biggest Lessons From Chronic Illness
03:18 Trying Nearly 200 Treatments
03:50 How an Engineering Background Changed His Approach
04:56 Becoming Your Own Health Advocate
06:09 The Connection Between Oxygen and Health
08:00 How Modern Homes Affect Our Environment
09:34 Chronic Fatigue, Brain Fog & the "Doom Loop"
11:38 Removing Environmental Stressors vs. Adding Therapies
13:42 The Biggest Mistakes During Recovery
15:54 Why Tracking Symptoms Matters
17:58 The Role of Oxygen in Mitochondrial Health
20:21 How Oxygen Reaches Your Cells
22:08 What Does the Research Say About Oxygen Therapy?
24:29 The Lungs and the Body's Elimination Processes
26:04 What Is Exercise With Oxygen Therapy (EWOT)?
28:08 Common Misconceptions About EWOT
29:11 Who Should Be Cautious About Oxygen Therapy?
29:55 Mold Illness, Lyme Disease & Chronic Fatigue
31:20 The Foundations of Health
32:33 Brain Fog, Fatigue & Oxygen Delivery
33:49 Environmental Illness and Inflammation
35:30 Why Health Quick Fixes Are So Appealing
37:49 The Future of Health Optimization
39:15 Why Recovery Is Different for Everyone
41:00 How Chronic Illness Changes Your Perspective
43:09 Why Recovery May Require Lifestyle Changes
45:18 Finding Hope After Years of Illness
48:37 What Recovery Really Means
50:00 About 1000 Roads
51:38 Final Thoughts

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🔵 About him: 

After suffering for years with strange medical conditions, Brad Pitzele was diagnosed with autoimmune arthritis in 2010 and malignant melanoma in 2014. Concerned that his treatments increased cancer risk, he began searching for a safer, more holistic path. Further testing revealed he also had Lyme disease and Bartonella. As his condition worsened with debilitating fatigue, brain fog, and mobility loss, Brad sought alternatives.  After years of trials, he discovered the power of oxygen to heal and used Exercise With Oxygen Therapy (EWOT) and Red Light Therapy to optimize his oxygen and recover his health.  Brad founded One Thousand Roads to share his discoveries with others and on the belief that healing should be effective, safe and accessible.

🔵 Follow him:

1000 Roads: https://www.onethousandroads.com   
Special listener offer: 1000roads.com/sicker
YouTube: 1000RoadsHQ
Instagram -  https://www.instagram.com/onethousandroadshq
YouTube  - https://www.youtube.com/@OneThousandRoadsHQ

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📖 Go Deeper: Read Chapter One Free
If you’ve ever wondered why mold can come back after remediation, why some people still feel sick after a home has been “cleared,” or what it actually takes to address mold correctly, I wrote The Mold Method for you. I’m giving you Chapter One for free. It starts with the case that changed the way I thought about mold remediation and ultimately shaped the approach I use today.

Read Chapter One FREE: https://www.homecleanse.com/free-chapter-one/?utm_campaign=mold-method-chapter-one&utm_source=youtube&utm_medium=video

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What happens when a mold inspection misses the problem? Or when you spend thousands on remediation, only to discover your home still has contamination?

In this episode of Never Been Sicker, Michael Rubino sits down with environmental inspector Michael Schrantz to discuss the mistakes, misconceptions, and industry practices that can leave homeowners confused, frustrated, and without answers.

Together, they share real experiences from the field, including inspections that overlooked important clues, remediation recommendations that didn't make sense, and situations where a home appeared to be fixed but underlying concerns remained.

They discuss why a mold inspection should go beyond collecting a few air samples, how hidden moisture problems can complicate an assessment, and why communication between inspectors and remediation professionals matters.

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CHAPTERS:
00:00 Introduction
01:21 Why mold remediation can fail
03:05 What makes a good mold inspection?
07:34 When inspection reports get it wrong
11:16 Why environmental problems are difficult to evaluate
18:07 Crawl spaces and overlooked contamination
21:09 Finding hidden mold
24:43 How wall cavity sampling works
28:41 Why remediation teams need better information
31:58 Inspectors and remediators working together
34:16 When remediation recommendations go too far
41:52 Finding the right professionals
46:41 The problem with demolition-free remediation
51:41 Resources for homeowners
54:23 Taking a deeper look at mold testing
01:05:49 Understanding DNA-based testing
01:14:54 What different mold species can tell us
01:23:09 Remediation products and cleaning methods
01:33:27 Why products alone aren't enough
01:46:56 Evaluating remediation approaches
01:58:27 What homeowners should understand
02:19:43 Final thoughts
02:20:17 Where to find Michael Schrantz

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🔵 About him: 

Michael Schrantz is the Founder and operator of Environmental Analytics, LCC. Environmental Analytics is a comprehensive indoor environmental quality consulting company that covers a wide range of environmental assessments for the residential, commercial, and medical sectors. Michael has over 27 years of active indoor environmental quality & building science experience. He has been involved in over 6,800 related projects expanding across the globe.

🔵 Follow him:

https://environmentalanalytics.net

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What if the fatigue, brain fog, weight gain, poor sleep, digestive issues, and hormonal changes you’ve been told are simply part of getting older actually deserve a closer look?

In this episode of Never Been Sicker, Michael Rubino sits down with Cynthia Thurlow, nurse practitioner, metabolic health expert, bestselling author, and leading voice in women’s health.
Cynthia shares a moment from her own health journey when her physician told her that weight gain was simply a normal part of aging. Her response? That couldn’t be enough of an explanation for women who don’t feel well, can’t sleep, lack energy, or suddenly feel like they don’t recognize themselves.

Michael and Cynthia explore why women with complex symptoms can fall through the cracks of conventional healthcare, and why hormones may only be one piece of a much larger puzzle.
They discuss brain fog, fatigue, weight-loss resistance, perimenopause, menopause, metabolic health, sleep, gut health, stress, environmental exposures, mold, and the importance of looking for underlying factors when the basics aren’t moving the needle.

If you’ve ever been told that feeling exhausted, gaining weight, sleeping poorly, or simply “not feeling like yourself” is just part of getting older, this conversation is for you.

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CHAPTERS:
00:00 Meet Cynthia Thurlow
00:41 Why Women Get Dismissed
03:07 Hormones, Metabolism & Mold
04:29 POTS & Mold Exposure
06:11 Cynthia’s Son’s Mold Exposure
08:26 The Mold Problem
09:03 Mold in Cynthia’s Home
10:40 Is It Really “Just Aging”?
13:49 Environmental Burden
17:07 Hidden Mold
18:37 Metabolic Health Today
20:24 Health Misinformation
24:52 Biggest Health Lies
25:12 The Calories Myth
28:29 Diet Dogma
29:54 Hormone Replacement Therapy
30:49 Sleep & Hormones
37:00 Losing Yourself in Perimenopause
39:25 The Perimenopause “Pause”
40:31 The Healthcare Problem
41:54 What Women Need to Hear
44:31 Getting a Second Opinion
46:00 Rapid Fire
49:03 The Menopause Gut
51:13 Gut Health & Toxins
53:27 Final Thoughts

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🔵 About her: 

Cynthia Thurlow is a nurse practitioner, nutrition and metabolic health expert, bestselling author, and TEDx speaker whose talk on intermittent fasting has reached more than 15 million views.

After nearly 20 years working in emergency medicine and cardiology, Cynthia shifted her focus toward nutrition, functional health, and the root causes of chronic health concerns. Her work became deeply personal after a serious health crisis landed her in the hospital for 13 days.
Today, she helps women navigate perimenopause and menopause, with a focus on energy, weight, food cravings, metabolic health, nutrition, and hormones.

🔵 Follow her:

https://www.cynthiathurlow.com/
https://www.instagram.com/cynthia_thurlow_/

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What if you feel perfectly healthy, but you have no idea how much better you could actually feel?

In this Most Replayed Moment from Never Been Sicker, Michael Rubino shares the story of working with two-time Super Bowl champion Logan Ryan.

Logan wasn't dealing with a major health crisis. He was a professional athlete performing at an elite level and, from his perspective, he felt fine.

But after Michael looked at his indoor environment, he found a moldy HVAC filter and other issues involving the home's air system. After changing the filter, introducing an air purifier in the bedroom, and beginning to address the indoor environment, Michael says Logan called him the next morning and told him:

“I had the best sleep of my life last night.”

Michael also recounts Logan saying his children hadn't complained about stuffy noses that morning after dealing with them for weeks.

That led to a bigger question:

If you think you feel fine, what are you comparing “fine” to?

Michael and Dr. Jill Crista discuss indoor air quality, environmental exposure, sleep, performance, and why creating a healthier environment isn't only a conversation for people who already feel sick.

🎧 This clip is from the full Never Been Sicker conversation with Dr. Jill Crista on mold, mycotoxins, environmental exposure, and the impact our indoor spaces can have on our health: https://youtu.be/HyZhwJc4HUc

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In this episode of Never Been Sicker, Michael Rubino sits down with Dr. Somer DelSignore to discuss why she believes some chronically ill children are being missed by conventional approaches to pediatric care.

Dr. DelSignore explains how her work evolved after encountering children with unusual combinations of behavioral changes, sleep problems, gut issues, neurological symptoms, chronic infections, and other concerns that weren’t improving with standard treatment.
Instead of looking at each symptom in isolation, she developed the RESET framework, which considers inflammation, environmental toxins, gut health, infections, and overall health together.

One of Dr. DelSignore’s biggest messages to parents:
“Symptoms are not the problem. It’s the body communicating.”

This conversation is about asking a different question. Instead of only asking how to suppress a symptom, what happens when we start investigating why it appeared in the first place?

🎙️ Never Been Sicker is hosted by indoor air quality expert Michael Rubino.

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CHAPTERS:
00:00 Intro
00:21 Why chronically ill children may be getting missed
01:38 The patients who changed how Somer practiced medicine
03:53 The RESET framework
05:56 The biggest misconception about chronic childhood illness
07:08 Mold exposure in chronically ill children
08:40 Is mold underdiagnosed in pediatrics?
10:09 Why environmental exposure can be overlooked
11:53 Are we normalizing dysregulation in children?
13:02 The connection between mold and Lyme
14:52 The biggest mistakes families make with mold illness
17:25 Mold, toxins & autism
18:44 Biological factors behind developmental and behavioral issues
19:49 Why aren't we talking more about neuroinflammation?
21:52 What parents should do when their child's behavior suddenly changes
22:37 Sudden rage, OCD, anxiety & intrusive thoughts
24:26 What pediatric medicine gets wrong
26:03 How pediatric healthcare could change
26:45 What will medicine understand differently in 20 years?
28:56 What today's pediatricians may be missing
30:03 What worries Somer most about the next generation
32:24 What gives her hope
33:27 The remarkable recovery of a critically ill 12-year-old
38:22 Rapid-fire questions
40:50 What to tell a parent who knows something is wrong
41:41 Where to find Dr. Somer DelSignore
43:00 Closing Pasted text

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Dr. Somer DelSignore is a board-certified pediatric provider and an advocate for root-cause medicine. With more than twenty years of clinical experience, her practice — Hudson Valley Integrative Health in Beacon, NY — draws families and adults from across the country and Europe who have moved through the standard medical system without answers. Combining her training with both  Dr. Richard Horowitz and Dr. Kenneth Bock, she has culminated her experiences infusing her own integrative beliefs to create the R.E.S.E.T. protocol, a clinical framework for diagnosing and treating multi-system illness. Her work is to demystify chronic illness in children— to think across systems where the standard model thinks within one specialty at a time.

🔵 Follow her:

https://www.hudsonvalleyintegrativehealth.com/

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A mold inspector spent about 20 minutes in Brian Karr’s apartment, took an air sample, and told him there wasn’t a mold problem.

But that wasn’t the end of the story.

After Brian began experiencing unexplained symptoms, a more thorough investigation uncovered what the original inspection had missed. Water from a major leak had traveled through the ceiling and walls, and Brian describes realizing he had been “living and sleeping in a toxic box” with mold affecting all four walls of his bedroom.

In this Most Replayed Moment from Never Been Sicker, Brian Karr and Michael Rubino break down why traditional air sampling can miss hidden mold and why understanding where mold actually grows matters when testing a home.

Brian also discusses findings from an internal comparison he conducted involving air sampling, while Michael breaks down just how small an air sample can be compared with the total volume of air inside a room.

Michael puts it simply:

“That’s like you’re looking at one drop of water in an entire ocean and saying, ‘Yeah, the whole ocean’s clean, guys. Good news.’”

If an inspection says everything is fine but something still doesn’t add up, this conversation explains why the testing method matters.

🎧 This clip is from the full episode of Never Been Sicker with Brian Karr. Watch the full episode for their complete conversation on hidden mold, mold inspections, testing, remediation, and creating a healthier indoor environment.

https://www.youtube.com/watch?v=zoXDiNRV3BA

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Dr. Diane Mueller was so sick that one day, during a five-minute walk around her neighborhood, she suddenly couldn't remember how to get home.

She was experiencing significant pain, brain fog, headaches, chronic fatigue, and neurological symptoms. Yet after seeing multiple doctors, her labs kept coming back normal.

Eventually, Diane began searching for answers herself.

She tested herself for Lyme disease and mold illness, and that discovery ultimately changed not only her own health journey, but the way she practices medicine today.

In this episode of Never Been Sicker, Michael Rubino sits down with Dr. Diane Mueller to explore why chronic illness can be so difficult to unravel and why the answer is often more complicated than finding one diagnosis.

They discuss Lyme, mold exposure, environmental toxins, testing limitations, mold colonization, autoimmune disease, relationships during chronic illness, and why two people can live in the same environment but experience completely different health outcomes.

Dr. Diane also explains why she believes chronic illness should be approached as a puzzle with multiple pieces rather than a search for one singular “root cause.”

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CHAPTERS:
00:00 Meet Dr. Diane Mueller
00:28 She Forgot Where She Lived
02:25 “I Thought I Was Dying”
03:36 When Doctors Couldn't Find Anything Wrong
04:50 Discovering Lyme & Mold Illness
06:33 How Being a Patient Changed Her Practice
09:45 It's Not in Your Mind
13:58 When Your Spouse Doesn't Believe You're Sick
17:08 How Chronic Illness Impacts Relationships
22:30 Mold, Lyme or Both?
24:50 The Problem With Mold Testing
27:31 The Dust Test & Testing Your Home
29:35 Can Mold Colonize the Body?
30:32 Environmental Toxins & Chronic Illness
33:05 Severe Symptoms That Improved After Mold Exposure Was Addressed
34:42 What Conventional Medicine Gets Wrong
37:18 Autoimmune Disease & Environmental Triggers
40:52 What Diane Couldn't Say 15 Years Ago
44:59 Diane's Current Health Routine
46:41 Rapid Fire
48:31 The Biggest Lie About Chronic Illness
50:38 A Message for Anyone Who Feels Hopeless
52:21 Where to Find Dr. Diane Mueller

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Dr. Diane Mueller, ND, DAOM
Dr. Diane Mueller has been where you are. She knows the exhaustion of being told your labs are normal when you feel anything but. She knows what it's like to sit in a doctor's office and be told it's stress, or anxiety, or that you just need to sleep more — while knowing deep down that something is genuinely wrong. She battled chronic Lyme disease and mold illness herself — and she found her way through. She built My Lyme Doc because no one should have to fight as hard as she did just to get help.

When you work with Dr. Mueller, you are not a file or a symptom checklist. She will sit with you, hear your whole story, and take it seriously. Her approach is gentle, thorough, and always guided by what feels right for you. She knows this journey is exhausting — and she is in your corner every step of the way.

🔵 Follow her:

https://mylymedoc.com/
https://drdianemueller.com/
https://www.instagram.com/mylibidodoc/

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What if you're doing everything to heal from mold, but you're still being exposed every single day?

In this episode of Never Been Sicker, Michael Rubino sits down with Brianne Quinn, a board-certified integrative health practitioner and founder of Ohana Wellness Company, to unpack the complicated relationship between mold exposure, chronic illness, histamine, the nervous system, Lyme, gut health, and environmental health.

Brianne shares the story of a teenage client who experienced severe fatigue and eventually lost her hair. Testing identified multiple molds and mycotoxins, and the family ultimately discovered a significant mold problem in the home after previous air testing had indicated everything was fine.

That leads Michael into one of the biggest problems he sees in mold investigations: relying on a small air sample as a screening tool for an entire room or home.

From there, the conversation goes much deeper.

One of the biggest takeaways? As Brianne puts it, trying to heal while you're still being exposed can be “like trying to drain a tub while the faucet is still on.”

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CHAPTERS:
00:00 Meet Brianne Quinn
01:15 The Teenage Mold Case That Changed Everything
04:13 Why Air Testing Can Miss Mold
06:25 The Biggest Misconception About Mold
09:35 Are Allergies Really “Normal”?
12:34 Brianne's Own Chronic Illness Story
16:09 Why Lyme Disease Is So Often Missed
18:02 Anxiety, Mental Health & Environmental Illness
21:03 Mold, EMFs & the Modern Home
22:29 How Often Is the Environment the Problem?
23:19 Why You Can't Detox While Exposure Continues
27:01 The Sneaky Mold Symptoms People Miss
29:48 Why Mold Affects Some People More Than Others
32:15 Is Mold Illness Becoming More Common?
33:31 The Problem With the Term “Black Mold”
35:21 Why DIY Mold Remediation Can Backfire
38:12 Histamine, MCAS & Mold
41:51 What Brianne Calls “Mold PTSD”
44:24 Have We Created an MCAS Generation?
47:13 The Most Overhyped Wellness Trend
50:34 Where Functional Medicine Gets It Wrong
53:06 The Biomarker Brianne Wishes Everyone Knew
54:20 Probiotics or No Probiotics?
55:17 The Supplement People Waste Money On
56:38 What Brianne Would Ban From Grocery Stores
58:11 Stress vs. Food vs. Indoor Air Quality
59:00 The Emotional Side of Chronic Illness
1:01:02 Brianne's Hardest Personal Healing Journey
1:03:43 Where to Find Brianne

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Brianne Quinn founded Ohana Wellness Company 10 years ago and has since become a global Wellness Educator & Advocate. Her true passion for uncovering the root cause of mysterious health issues makes her a valuable asset to clients, as they work together using a natural, whole-body approach to wellness.​
​
After nursing school, it was clear to Brianne that the conventional medicine space was set up to mask health issues, not understand why they existed in the first place. After making the switch over to functional medicine, she now uses her own personal triumph over chronic illness, along with 10+ years of education and experience in the fields of holistic health and preventative wellness to create personalized wellness programs designed to achieve her clients' goals. 
​
After 6 years of running a successful clinic in the New Orleans area, Brianne now lives in Kodiak, Alaska and helps people virtually all over the world while enjoying nature & the outdoors.

🔵 Follow her:

https://www.ohanawellness.com
https://www.instagram.com/ohana_wellness

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We spend roughly 90% of our lives indoors, but how often are our homes actually designed with our health in mind?

In this episode of Never Been Sicker, Michael Rubino sits down with Kelly Grace, a non-toxic architect, to uncover what goes into creating a truly healthy home.

Kelly explains why conventional architecture and building practices often prioritize cost, aesthetics, efficiency, and basic safety while overlooking how materials and design choices can affect the people living inside.

They dive into building materials, moisture and mold, ventilation, flooring, drywall, furniture, mattresses, air quality, and the hidden decisions that can make the difference between a beautiful home and a health-supporting one.

Kelly also reveals materials she personally avoids, why she believes drywall has no place in bathrooms, the problems she sees with popular flooring options like LVP, and why even brand-new homes can develop moisture problems.

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CHAPTERS:
00:00 Introduction
01:00 What Is a Non-Toxic Architect?
04:00 Why Kelly Started Designing Healthier Homes
07:00 Are Modern Homes Actually Built for Health?
10:00 The Problem With Conventional Building Materials
14:00 Mold, Moisture & Modern Construction
18:00 Why Kelly Wouldn't Put Drywall in a Bathroom
22:00 Building Codes vs. Human Health
26:00 The Ventilation Problem
30:00 Flooring a Non-Toxic Architect Avoids
34:00 Hidden Toxins in Furniture & Mattresses
39:00 Why New Homes Can Still Have Mold
44:00 Building a Healthy Home From Scratch
49:00 Healthier Changes You Can Make Right Now
54:00 Kelly's Biggest Healthy Home Takeaways
57:00 Where to Find Kelly Grace

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Kelly Grace is an accomplished architect based out of Washington DC, and the Managing Principal of Travis Price Architects, an award-winning architecture firm, widely applauded for their visionary aesthetics, informed by ecology, mythology, and technology.  TPA seeks to create an enduring archaeology for tomorrow, through culturally diverse inspirations, natural self-reliance, and high-performance building practices.

Kelly is known to many as the “NONTOXARCHITECT” on social media, where she shares her advice on material selections, design details, indoor air quality, water filtration, biohacking, EMF mitigation, moisture control, and much more.  She is dedicated to designing healthy buildings, using non-toxic products, to promote wellness habits and optimal living.  

Kelly is also a Founding Member of the Healthy Building Alliance, an up-and-coming platform to connect healthy building professionals; architects, builders, engineers, homeowners, consultants, and product manufacturers, to provide a network of resources and educational tools, based on proven building biology and building science principles.

Kelly and her husband Matt live in Davidsonville, MD with their three children, Atlas, Adelyn, and Roark, twenty chickens, and dogs Blue and Ruby.

🔵 Follow her:

@nontoxarchitect
@travispricearch
travispricearchitects.com 

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In this Most Replayed Moment from Never Been Sicker, Dr. Jill Crista shares a striking case involving a patient with Parkinson’s-like symptoms and signs of dementia who was found to have fungal growth in his sinuses. She explains what happened after it was removed, why mold can potentially colonize parts of the body, and how mycotoxins can continue to affect health beyond the initial exposure.

Michael and Dr. Crista also dive into why mold-related illness is so difficult to recognize, including preliminary research showing that 80% of mold-sick participants in their dataset weren’t aware of a current or past mold exposure.

This clip is taken from NBS #84: The Truth About Mycotoxins: Why You’re Still Sick After Mold Exposure | with Dr. Jill Crista.

🎧 Watch the full episode of Never Been Sicker to hear the complete conversation on mycotoxins, mold exposure, testing, treatment, and what people need to know about recovering from mold-related illness: https://www.themichaelrubino.com/the-truth-about-mycotoxins-why-youre-still-sick-after-mold-exposure/