EP. 212: Today I’m joined by Dr. Spencer Nadolsky, obesity specialist, Lipidologist, and founder of Vineyard, a cutting-edge direct care platform. We’re diving deep into the conversation you’ve been asking for: the real story behind GLP-1s, obesity as a chronic disease, and why treating it goes far beyond weight loss.

We break down everything from proper dosing, common side effects, and the dangers of vanity prescribing to the systemic issues with telemedicine and PBMs. Dr. Nadolsky and I also discuss strength training, preserving muscle mass, and how GLP-1s may support metabolic and cardiovascular health beyond their FDA indications.

This episode cuts through the noise and misinformation. If you care about metabolic health, this one’s essential.

Topics Discussed: 

What are the real benefits of GLP-1 medications beyond weight loss?

Is obesity truly a chronic disease, and how should it be treated?

What are the risks of GLP-1 vanity dosing and fast titration?

How do GLP-1s impact muscle mass and metabolic health?

Why are telemedicine and PBMs problematic for obesity treatment?

Sponsored By:

On This Episode We Cover: 

00:00:00 – Introduction 

00:02:48 – GLP-1 Dosing 

00:06:35 – Side Effects of Vanity Dosing

00:08:51 – Reducing GLP-1 Dosing

00:12:27 – Med Spas & Telemedicine Risks

00:14:20 – Slow Titration for Better Tolerance

00:18:44 – Pharma Profits & Overdosing

00:20:49 – Obesity Treatment Pre & Post GLP-1s

00:27:58 – Obesity Is a Chronic Disease

00:32:45 – Defining obesity 

00:36:16 – The Role of Genetics in Obesity

00:38:59 – Lifestyle Factors Beyond Genetics

00:40:46 – Insurance Barriers & PBM Costs

00:44:37 – Anti-GLP-1 Bias in Healthcare

00:46:22 – Why Strength Training Matters

00:51:39 – New Doctors & Role of AI

00:53:38 – Protecting Muscle on GLP-1s

00:58:55 – No Shortcuts to Health

01:02:01 – The Vineyard

Show Links:

Glp-1s Can Help Employers Lower Medical Costs In 2 Years, New Study Finds

Further Listening

GLP1 Uncovered FREE 4 Part Video Series 

Ozempic Done Right Playlist

EP. 202 | The Fight for Affordable GLP1s & the Truth About Big Pharma | Dave Knap

Check Out Dr. Spencer

Vineyard

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Website

Podcast

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