Peptide Q&A #6 – Perimenopause Stack, IGF-1 LR3 Cycles, DSIP Sleep Fix, CJC w/wo DAC, NAD Dosing & RETA Without Appetite Loss

Welcome back, warriors! In this week’s Peptide Q&A, JD Denham and William T. Haas get tactical on dosing, timing, and stacking—plus how to troubleshoot side effects without wasting vials.

We cover:

🌡️ Perimenopause Relief (47F): Sermorelin vs CJC/IPA, TA-1 (thymosin-α1) & TB-500 for inflammation, Selank/Semax for mood, PT-141 for libido

💪 IGF-1 LR3: What 1 mg really covers, 50–100 mcg dosing, 4–6 week “go hard” cycle, pairing with tesamorelin/HGH

💧 Menopause Dryness: PT-141 & (optionally) Linsidomine-2 what actually helps

🧔 605 Total T at 42: Enclomiphene vs just starting TRT, where CJC/IPA fits, IGF-1 for lean mass

🦴 Arthritis & Osteoarthritis (77F): Where to pin BPC-157/TB-500 for back pain, starter dosing, add TA-1 for inflammation/immune

🧴 Blue Goddess (GHK-Cu + Snap-8): Dermaroller + copper → headaches? Safe A/B testing to isolate the cause

⚡ NAD+: Is 1000 mg/month sub-Q the same as an IV “cycle”? Updated dosing philosophy (smaller, steady, 3×/week)

🧪 CJC-1295 DAC vs no-DAC: Half-life tradeoffs, why no-DAC often feels “more natural,” handling water retention

😴 Short Sleep Lifters: DSIP basics, fasted windows for PM tesamorelin, and why trimming 2.5-hr workouts can buy better recovery

🫀 RETA Without Appetite Suppression: Replicating benefits (insulin sensitivity, liver, cardio) with SS-31, 5-Amino-1-MQ, AOD 9604, tesamorelin

🧷 GHRH + GHRP Combo: Tesamorelin + Ipamorelin—equal doses, blend vs separate, and the AM HGH + PM secretagogue cadence

💡 Peptides are tools not shortcuts. Stack them with training, protein, and sleep for results that stick.

👉 Drop your questions below for next week’s Q&A.

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