Podcast Notes Playlist: Latest Episodes

Bill and Grant welcome the incomparable Felix Zulauf to The End Game.What follows is a true masterclass in macro thinking as Felix joins a complicated series of dots to lay out both a cohesive vision of the present, and an impressive roadmap for the future.The likely end of a 40-year bull market in bonds, the all-important inflation vs deflation debate as well as gold, the dollar and so much more all come under Felix's acute gaze.Once again, this episode of The End Game will have your head spinning...

Ed Latimore, professional boxer, chess player, author, influencer, social media guru, and even physicist! In this episode, I talked to him about Ed about how he looks at things differently, and what makes him want to dabble into different professions, learning different skills, and how does he get out of his comfort zone! Before the podcast ended, we also talked about the power of annoyance, which have proof effective in some scenario.

I write about all my podcasts! Check out the full post and learn what I learned at jamesaltucher.com/podcast.

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Podcast Notes

• Medicine is an art: sometimes you have to make decisions with less than perfect information
• There is often a disconnect between what patients perceive as the benefit of a procedure versus what doctors know as the likely outcome 
• Despite a lot of propaganda, we really haven’t had a lot of success in cancer
• Oncology drug studies are conducted on patients who don’t resemble what is happening in reality
• New drugs are often tested against the oldest, weakest drug in the space to prove efficacy and game the system
• Conflicts of interest and financial influence distort the true outcomes and benefit to the end-user 
• We need practitioners with no financial relationship with companies that make the product
• Drug research needs to focus on improved quality of life, not just arbitrary cut-points (e.g, measuring tumor size)

Read the full notes @ podcastnotes.org

Vinay Prasad is a practicing hematologist-oncologist who doubles as a “meta-researcher,” studying the quality of medical evidence, health policy, and clinical trials. In this episode, Vinay discusses the differences in clinical treatment from the existing medical evidence, often leading to useless, or even harmful, outcomes for patients. With a focus in oncology, he takes a deep dive into the field’s structural problems, which include the disconnect between progress and funding, drug costs, and financial conflicts of interest. He concludes with his “six hallmarks of successful cancer policy” as a potential roadmap to sustained progress against cancer and a way to avoid repeating the policy and practice mistakes of the past.

 

We discuss:

• Vinay’s background and unique perspective [3:15];
• Medical reversal—the disconnect between research findings and clinical applications in medicine [10:15];
• The uniquely challenging field of oncology [22:45];
• The importance of bedside manner with cancer patients [30:00];
• Structural problems in oncology—Problem #1: Huge costs for small improvements [37:00];
• Structural problems in oncology—Problem #2: Medical reversal—when medical practices are adopted based on low levels of evidence [40:15];
• Structural problems in oncology—Problem #3: Slow progress in cancer research (despite all the hype and propaganda) [45:00];
• Structural problems in oncology—Problem #4: The burden of payment is not matched with those making treatment decisions [54:45];
• “No-brainer” moves in oncology [1:06:45];
• “Fool’s gold” treatments in oncology [1:09:30];
• The six hallmarks of successful cancer policy [1:16:00];
• Cancer policy hallmark #1: Independence [1:18:00];
• Cancer policy hallmark #2: Evidence [1:28:15];
• Cancer policy hallmark #3: Relevance [1:31:30];
• Cancer policy hallmark #4: Affordability [1:32:00];
• Cancer policy hallmark #5: Possibility [1:47:00];
• Cancer policy hallmark #6: Agenda [1:52:00];
• Tumor genome sequencing and liquid biopsies [1:54:30];
• Vinay’s clinical philosophy, being skeptical without being too contrarian, and practicing medicine without perfect information [2:03:30]; and
• More.

Learn more: https://peterattiamd.com/

Show notes page for this episode: https://peterattiamd.com/VinayPrasad 

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Podcast Notes Key Takeaways

• Triceps have nothing to do with wrist rotation: supinated versus pronated grip will not have an impact on the efficacy of a triceps exercise
• Partial reps have a place in the context of a limited range of motion but the goal should always be to build a full range of motion
• Always train to the fullest range of motion you have control over
• If working with partial reps include correctional movements to improve the functional range of motion
• Lack of hydration can make you think you are hungry
• Tips if you’re always hungry: make sure you are drinking enough water, eat smaller meals throughout the day with snacks between
• A good chiropractor is a movement specialist who will explain movement patterns and offer correctional exercises, not just lay you on the table for adjustments week after week

Read the full notes @ podcastnotes.org

In this episode of Quah (Q & A), Sal, Adam & Justin answer Pump Head questions about the advantages of using a supinated grip over a pronated grip for tricep exercises, the validity of training with partial reps or a limited range of motion to save joints, strategies to deal with a big appetite, and the pros & cons of chiropractic care.

• Mind Pump’s favorite comic book heroes and villains. (4:38)
• Mind Pump reminisces on their childhood collections. (7:30)
• Wild wildlife stories with Mind Pump. (14:43)
• Qantas Airways ‘flight to nowhere’. (21:26)
• Mind Pump’s Halloween plans. (25:10)
• Welcome back Mind Pump sponsor Caldera! (26:05)
• Predictions for the US election. (29:21)
• Fun Facts with Justin: Do you believe in superstitions? (33:10)
• Get your own Pluto Pillow! (38:25)
• Strange Science with Sal. (40:30)
• Kids will blow your mind! (43:03)
• Mind Pump Investments. (46:19)
• #Quah question #1 – When is it more advantageous to use a supinated grip over a pronated grip for tricep exercises? It’s obviously risker when doing exercises like skull crushers, but does it hit the tri’s at a different angle? (48:23)
• #Quah question #2 – What would you tell a client who was told they only have to train with partial reps or a limited range of motion to save joints? (54:03)
• #Quah question #3 – I have a big appetite and I always feel hungry. What are some strategies you have used to help? Are there foods you have used to hack big appetites? (1:00:25)
• #Quah question #4 – There is a lot of skepticism on chiropractic therapy and its origins. What are your opinions and do you think it helps? (1:04:56)

Related Links/Products Mentioned

• October Special: MAPS Anabolic and No BS 6-Pack Formula
• Watch: Mountain lion stalks trail runner for six minutes, until…
• Qantas Airways 'flight to nowhere' that sold out in minutes takes off
• Visit Caldera Lab for an exclusive offer for Mind Pump listeners! **Code “mindpump” at checkout for the discount**
• Trump or Biden? Peruvian shamans try to predict U.S. election winner
• Tourist returns stolen artifacts to Pompeii after experiencing bad luck
• The Rise of Superman: Decoding the Science of Ultimate Human Performance
• Visit Pluto Pillow for an exclusive offer for Mind Pump listeners! **Promo code “MINDPUMP” at checkout for 10% off**
• Tennessee teenager's homemade fusion reactor lands Guinness record
• Popular video game platform Roblox announces public offering that could value the company at $8 billion
• Peloton will leap another 14% as new products open the door to 5 million potential subscribers, BofA says
• Build Your Triceps with Angles – Mind Pump TV
• Effect of range of motion on muscle strength and thickness
• Catching Up and Food and Stress Management » Paul Chek's Blog
• Mind Pump's Response to Joe Rogan Episode #984 with Yvette d'Entremont
• Mind Pump Podcast – YouTube
• Mind Pump Free Resources

People Mentioned

• Justin Brink DC (@dr.justinbrink)  Instagram
• Dr. Jordan Shallow (@the_muscle_doc)  Instagram
• MoveU's (@moveu)  Instagram

Podcast Notes Key Takeways

• “GPT-3 is a text-completion artificial intelligence. Specifically, it’s in the category of natural language processing artificial intelligence. This is a technology developed by OpenAI which is a machine learning AI company originally started by Elon Musk now run by Sam Altman.” – Hassan Osman
  • “Basically what it does is it takes a piece of text that you give it and it tries to complete that text”
  • The AI is based on writing from a small subset of the internet
• After publishing his first GPT-3 generated post on Substack, Liam got 26,000 unique readers in 2 weeks
  • Liam never revealed the text was written by an AI and the public liked the writing on its own accord
• Liam believes that while GPT-3 is attention-grabbing, it currently doesn’t have much practical use
  • A far more practical text-based AI would be one that can analyze information and summarize it for the public
• “I think in the near future you are going to see a lot of writers who are using GPT-3 or similar models to basically accelerate the writing process” – Hassan Oman
• Liam believes GPT-3 will make it easier to become a writer, but it will also raise the bar for the quality of content that people read

Read the full notes @ podcastnotes.org

Liam Porr discusses how he used GPT-3 to publish blog posts and articles, as well as the pros and cons of using artificial intelligence models for writing nonfiction content in the future.

Podcast Notes Key Takeaways

• “Once you can get people to laugh at something, they never take that thing as seriously ever again” – Paraphrased quote by Voltaire
• Comedy and tragedy may seem like polar opposites at first, while they are actually very similar
  – They aim to offer a different perspective
  – In tragedy, the sacrifice of a hero can evoke a socio-political change in society
  – In comedy, the socio-political situation is ridiculed to cause a shift in the public consciousness
• Theories of laughter
  • Superiority Theory
    • We laugh at things when we feel superior to some element of the joke or situation
  • The Relief Theory
    • Sees laughter as a psychological tool to help us release tension
  • The Incongruity Theory
    • Aristotle said that the easiest way to make an audience laugh is to set some expectations and then violate them
  • Henri Bergson’s Hybrid Theory
    • He synthesizes the strongest parts of the other theories and adds a social element of laughter
      • Laughter has the function to regulate our culture and community

Read the full notes @ podcastnotes.org

Today we begin our discussion on the work of Bergson. 

Podcast Notes Key Takeaways

• We cannot assess decision quality objectively
  • What we can assess is the outcome of that decision
  • The problem is that we tend to confuse a good outcome with a good decision and vice versa
• Dealing with The Hindsight Bias
  • Create a knowledge tracker asking yourself:
    • What information did I know, or was knowable, beforehand?
      • Could I have know other relevant information at a reasonable cost?
    • What decision did I make?
    • What things were revealed afterward?
    • What was the outcome?
    • What other outcomes could have happened and what were their probabilities?
  • It’s way better to start tracking all this information as part of the decision-making process
• Increased uncertainty from COVID-19, requires us to document our decision-making processes even more accurately that we normally would
• When we have a thesis, we should ask ourselves how we could find out if our thesis is wrong
  • “If that’s not the way you are thinking you will not be successful, except by accident” – Annie Duke

Read the full notes @ podcastnotes.org

In this episode of Infinite Loops we spoke with Annie Duke, former professional poker player, decision-making expert, and best-selling author. Her latest book is How to Decide: Simple Tools for Making Better Choices, which was released this week. In this conversation, we cover:

• COVID-19 and decision-making
• Resulting and the 2016 election
• What drove Annie to write her new book
• Writing as a powerful tool for testing your knowledge
• And MUCH more.

Follow Annie on Twitter at https://twitter.com/AnnieDuke , and find her new book here https://www.amazon.com/gp/product/0593418484?tag=randohouseinc13176-20.

Matthew McConaughey — The Power of “No, Thank You,” Key Life Lessons, 30+ Years of Diary Notes, and The Art of Catching Greenlights | Brought to you by Wealthfront automated investing, Helix Sleep mattresses, and Magic Spoon cereal

Matthew McConaughey (@McConaughey) is a Texas native and one of Hollywood's most sought-after leading men. A chance meeting in Austin with casting director and producer Don Phillips led him to director Richard Linklater, who launched the actor's career in the cult classic Dazed and Confused. Since then, he has won an Academy Award for his portrayal of Ron Woodroof in Dallas Buyers Club, appeared in more than 40 feature films that have grossed more than $1 billion, and has become a producer, director, and philanthropist with his Just Keep Livin' Foundation—all the while sticking to his Texas roots and "jk livin'" philosophy.

McConaughey also serves as creative director for Wild Turkey and has co-created his own bourbon, Longbranch. He serves as Minister of Culture/M.O.C. for the University of Texas Athletic Department and the Austin FC Soccer Club, where he is part owner. McConaughey will launch his first book, Greenlights, on October 20, 2020.

He currently resides in Austin, Texas, with his wife Camilla and their three kids while he is a professor at the University of Texas in Austin.

Please enjoy!

This episode is brought to you by Wealthfront! Wealthfront pioneered the automated investing movement, sometimes referred to as ‘robo-advising,’ and they currently oversee $20 billion of assets for their clients. It takes about three minutes to sign up, and then Wealthfront will build you a globally diversified portfolio of ETFs based on your risk appetite and manage it for you at an incredibly low cost. 

Smart investing should not feel like a rollercoaster ride. Let the professionals do the work for you. Go to Wealthfront.com/Tim and open a Wealthfront account today, and you’ll get your first $5,000 managed for free, for life. Wealthfront will automate your investments for the long term. Get started today at Wealthfront.com/Tim.

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This podcast episode is also brought to you by Helix Sleep! Helix was selected as the #1 best overall mattress pick of 2020 by GQ magazine, Wired, Apartment Therapy, and many others. With Helix, there’s a specific mattress for each and every body’s unique taste. Just take their quiz—only two minutes to complete—that matches your body type and sleep preferences to the perfect mattress for you. They have a 10-year warranty, and you get to try it out for a hundred nights, risk free. They’ll even pick it up from you if you don’t love it. And now, to my dear listeners, Helix is offering up to 200 dollars off all mattress orders plus two free pillows at HelixSleep.com/Tim.

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This episode is also brought to you by Magic Spoon Cereal! Magic Spoon is a brand-new cereal that is low carb, high protein, and zero sugar. It tastes just like your favorite sugary cereal. Each serving has 12g of protein, 3g of net carbs, 0g of sugar, and only 110 calories. It’s also gluten free, grain free, keto friendly, soy free, and GMO free. And it’s delicious! It comes in your favorite, traditional cereal flavors like Cocoa, Frosted, and Blueberry.

Magic Spoon cereal has received a lot of attention since launching last year. Time magazine included it in their list of Best Inventions of 2019, and Forbes called it “the future of cereal.” My listeners—that’s you—get free shipping and a 100% happiness guarantee when you visit MagicSpoon.com/Tim and use code TIM.

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My guest today is James Altucher, the author of several books including the WSJ bestseller Choose Yourself! He is an entrepreneur, angel investor, chess master, comedian, and prolific writer. He is also the podcast host of "The James Altucher Show"...

Stuck in a bad situation, even when the prison doors are left wide open, we sometimes refuse to attempt escape. Why is that?

In this episode learn all about the strange phenomenon of learned helplessness and how it keeps people in bad jobs, poor health, terrible relationships, and awful circumstances despite how easy it might be to escape any one of those scenarios with just one more effort. In the episode, you'll learn how to defeat this psychological trap with advice from psychologists Jennifer Welbourne, who studies attributional styles in the workplace, and Kym Bennett who studies the effects of pessimism on health.

See omnystudio.com/listener for privacy information.