Podcast Notes Key Takeaways
- The Background
- Telomeres are structures comprised of short sequences of DNA nucleotides present on the ends of our chromosomes
- They protect the chromosomes/genome from damage
- Telomere length is a useful biomarker associated with aging
- Telomeres shorten every year of your life as a function of cell division
- What kinds of things accelerate the shortening of telomeres?
- A negative environment (excess stress – resulting from things like job loss, financial difficulties, trauma, or domestic violence)
- Excess chemical exposure to BPAs, Roundup, and heavy metals
- Exposure to high levels of air pollution
- How can you delay or even reverse telomere shortening?
- Avoid eating processed meats, sugary drinks, and high-sugar foods
- Eat more fiber
- Exercise frequently
- Avoid smoking
- It is EXTREMELY IMPORTANT to consider the health of both the mother AND father prior to conceiving a child
- Stress (resulting from things like job loss and financial difficulties) during pregnancy (as well as the year prior to giving birth) is associated with shorter telomeres in the offspring
- One study found that the expression of over 500 genes in the sperm of obese men was altered compared to that of healthy men (genes having to due with metabolism, cognitive function, etc.)
- Why does telomere length at birth matter?
- It’s one of the biggest determinants of telomere length later in life
- In Summary
- Small, moderate health behaviors add up over decades to improve longevity, contribute to better telomere length, and reduce inflammation
Read the full notes @ podcastnotes.org
Elissa Epel, PhD, is a Professor in the Department of Psychiatry at the University of California, San Francisco where she serves as the director of the Aging, Metabolism, and Emotions Center. Her research centers on the mechanisms of healthy aging and the associations between stress, telomere length, addiction, eating, and metabolic health.
In this episode, we dive deep into the world of telomeres, the length of which is one of the useful biomarkers scientists have for getting a sense of the differences between how individuals or groups of individuals age. Telomere shortening is both a cause and a symptom of aging and plays key roles in not only how long we live, but in how well. Lifestyle factors such as poor nutrition and smoking can accelerate telomere shortening by generating oxidative stress and inflammation.
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Submit your raw genetic data. You can find the Telomere report at foundmyfitness.com/genetics.