Podcast Notes Playlist: Latest Episodes

In this episode, Charlie Hoehn explains the secrets behind why some books are unforgettable, and others no one seems to remember. He shares his journey of helping authors transform their ideas into best-selling books and provides actionable advice on structuring, writing, and marketing a book. You'll learn how to craft titles that make people want to read your book, design compelling covers that stand out on the shelves, and use certain strategies to engage readers effectively depending on the ideas you communicate. Hoehn also shares the psychology behind book promotion, how to leverage feedback, and the dynamics of traditional versus self-publishing. Whether tackling a novel or email, this episode will transform how you write and communicate.

Charlie Hoehn is the founder of Author.Inc and a 3-time New York Times bestselling editor. He's the mind behind some of the influential books from Tim Ferriss, Ramit Sethi, Codie Sanchez, and Noah Kagan. Charlie's expertise has helped sell over 10 million books.

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(00:00) Intro

(03:04) Helping Authors Succeed

(03:38) Writing for a Specific Audience

(07:14) The Importance of Real Feedback

(10:18) Traditional vs. Self-Publishing

(20:50) The Economics of Self-Publishing

(24:42) The Art of Book Cover Design

(30:29) Crafting a Compelling Title

(36:42) The Importance of Book Structure

(47:22) Editing: The Final Touch

(51:35) Book Sales Percentiles

(52:32) The Harsh Reality of Book Sales

(54:20) The Emotional Impact of Writing

(55:12) Dealing with Compliments and Criticism

(58:24) The Quest for Bestseller Lists

(1:00:04) The Complexities of Hitting the New York Times List

(1:12:25) Leveraging AI in Writing

(1:20:21) Effective Marketing Strategies for Authors

(1:28:14) Creating Evergreen Content

(1:35:30) The Importance of Authenticity in Writing

(1:40:54) Final Thoughts

Parmita Mishra is a computational biologist and the founder & CEO of Precigenetics, a company aiming to become a rocket to precision medicine.

Parmita is deeply knowledgeable about cutting-edge biology, particularly epigenetics — how behavior and environment can affect gene function without altering genetic code. Her passion for advancing our understanding of diseases is inspiring (and contagious: OSV is an investor in Parmita’s company!)

In our conversation, Parmita and I discuss everything from the curious case of male baldness to how her parents have saved 50,000 lives. 

I hope you enjoy this conversation as much as I did. For the full transcript, highlights, and bucketloads of other goodies designed to make you go, “Hmm, that’s interesting!”, check out our Substack.

Important Links:

• LinkedIn
• Twitter
• Website
• Precigenetics Twitter
• Preciginetics launch post

Show Notes:

• Explaining epigenetics to a golden retriever
• The curious case of male pattern baldness
• How to think about biology: start from first principles & beware binary thinking
• The lens you look through determines what you see
• The problem of data collection in biology
• Why the FDA needs to change its approach
• Why we still don’t understand the human brain
• Garry Tan’s advice: “Get an idea. Get a co-founder.”
• What’s been surprising about foundership?
• Failure is a ladder
• Obsession & how Parmita’s parents have saved 50,000 lives
• The most surprising things about America
• Parmita as World Empress

Books Mentioned:

• What is Life?; by Erwin Schrodinger
• I should have loved biology; by James Somers
• Gödel, Escher, Bach: An Eternal Golden Braid; by Douglas Hofstadter
• The Hypomanic Edge: The Link Between (A Little) Craziness and (A Lot of) Success in America; by John D. Gartner