Dr. Jesse Reilly shares his background in working with runners and endurance athletes and his approach to pain management. He emphasizes the importance of an evidence-based approach and individualized care. He discusses the role of the brain in interpreting pain and the need to find a balance between pushing through discomfort and avoiding injury. Dr. Reilly also addresses the use of the RICE protocol and the importance of movement in recovery. He explores the mindset and mental strategies that can help athletes navigate pain during races. The conversation concludes with a discussion on the evolution of sports performance over the past century. In this conversation, Dr. Jesse Riley discusses the role of strength training in ultra-endurance events and the importance of individualized treatment plans. He emphasizes the need for consistency and realistic expectations in training and highlights the value of addressing mental health and overall well-being. Dr. Riley also offers insights into virtual treatment options and the benefits of a cash-based model. The conversation concludes with a discussion on favorite training foods and gear, as well as the ongoing pursuit of personal goals.