In this informative podcast episode, Dr. Mimi Guarneri, a board-certified cardiologist and pioneer in Integrative Holistic Medicine, shares her expertise on women and cardiovascular disease. Dr. Guarneri discusses her approach to treating cardiovascular disease risk with a personalized heart health perspective. She emphasizes going "Beyond Cholesterol" when assessing cardiovascular risk in women, taking a more proactive and comprehensive approach to heart conditions. This episode represents Dr. Guarneri's continued commitment to educating both medical professionals and the public about integrative approaches to cardiovascular health, with a special focus on women's unique needs and challenges.

On this episode of Redefining Medicine, Dr. Austin Perlmutter—board-certified internal medicine physician, bestselling author, and educator—explores the powerful connection between neuroinflammation, mindset, and overall health. He shares how lifestyle inputs such as diet, environment, sleep, and stress shape our brain and body, and why inflammation isn’t always harmful but must be balanced. Listeners gain practical strategies to reduce “stuckness,” improve resilience, and reclaim cognitive clarity in today’s distracted world.

Dr. Helen Messier, M.D., Ph.D., Chief Medical Officer of Fountain Life, joins us on our latest episode of Redefining Medicine to discuss transforming healthcare from reactive to proactive through preventative health and longevity medicine.

In this fascinating conversation, Dr. Messier shares insights from her extensive career dedicated to harnessing data to close the translational gap in medicine. As both a scientist and certified family practice physician, she discusses:

1. How integrating multi-omics data and digital health technologies can revolutionize clinical care

2. The role of AI technologies and advanced diagnostic testing in early detection of conditions like cancer, cardiac, metabolic, and neurodegenerative diseases

3. Her journey from founding a network of concierge medical practices to her leadership role at Fountain Life

4. Practical approaches to preventative medicine that can significantly impact patient lifespan and well-being

Don't miss this opportunity to hear from one of the leading voices in precision medicine who is actively working to redefine our approach to healthcare.

Dr Nichola Conlon is a molecular biologist specialising in the study of cellular ageing. After a career in drug development, Dr Conlon founded Nuchido Laboratories to deliver disruptive innovation in the field of anti-ageing, rejuvenation and healthspan. Dr Conlon has a passion for sharing the latest science and is an accomplished speaker, with a skill for translating advanced science to help educate and support the wider population, encouraging people to age well and achieve their optimal life experience.

Lori Esarey is a certified family nurse practitioner with over 25 years of experience who founded her clinic in 2006 based on the philosophy that proper nutrition can effectively manage disease. With a Master's in Nutritional Medicine from USF and board certification in anti-aging and restorative medicine, she helps patients identify and reverse unhealthy lifestyle habits. As a national speaker on health, nutrition, and functional medicine business practices, Lori is also the cofounder of Synergee, LLC, which equips emerging functional medicine providers with essential skills and knowledge to become leaders in their field. Together with her clinical team, she ensures patients receive the necessary tools and guidance to improve their healthspan and optimize their overall wellbeing.

When not transforming patients' lives, Lori enjoys beach walks, reading, personal development, and spending quality time with her friends, children, and three grandchildren.

Kelly Engelmann began her medical career while still in high school, working in an OB-GYN clinic. After earning degrees from Hinds Community College and the University of Mississippi, she graduated top of her class, receiving the Christine Olavee Award. With her Master's in Nursing and Family Nurse Practitioner training from the University of Southern Mississippi, Kelly founded Enhanced Wellness Living Functional Medicine Clinic in 2004. Her practice focuses on identifying underlying causes of symptoms and treating them through nutritional education, empowering patients to prevent chronic illness. Kelly holds a Master's Degree in Metabolic and Nutritional Medicine from the University of South Florida's Medical School and completed the Fellowship in Anti-Aging Medicine. In 2019, she co-founded Synergee, a network of Integrative Medicine practitioners dedicated to expanding access to Functional Medicine.

An active community member with Pinelake Church, Kelly and her team regularly participate in charitable initiatives. A lifelong learner and former marathon runner, she enjoys bicycling, yoga, traveling, and cooking for her family.

Dr. Lucia Aronica is a Stanford University Lecturer and leading expert in epigenetics and personalized nutrition with over 17 years of research experience. Her work has been featured on Netflix, TEDx, and in prestigious scientific journals.

At Stanford, she developed professional courses in nutritional epigenetics and the biology of longevity. Her groundbreaking research explores how dietary patterns influence gene expression and aging pathways, with particular focus on how food-derived compounds modify epigenetic marks to promote health and prevent disease.

Drawing from her Italian heritage, Dr. Aronica uniquely advocates for pleasure as a compass for health, demonstrating how cultural food traditions combined with scientific innovation can optimize genetic expression. Her approach blends rigorous scientific methodology with practical applications, translating complex concepts into actionable strategies from lab to kitchen. Through her teaching, research, and public outreach, Dr. Aronica is advancing our understanding of how lifestyle factors can help us outlive our DNA and rediscover the joy of healthy living through small, sustainable daily actions.

Dr. Jennifer Pearlman is a medical doctor specializing in women's health and wellness. As a NAMS Certified Menopause Practitioner (NCMP), she brings a decade of experience from the Menopause Clinic at Mount Sinai Hospital in Toronto. The Ontario Medical Association has recognized her expertise with a focus practice designation, enabling her to serve as a consultant to other physicians in women's health.

Dr. Pearlman has developed significant expertise in cosmetic medicine, embracing a holistic approach to facial and body rejuvenation based on her philosophy that beauty emanates from within. She has trained other physicians in cosmetic injection techniques and remains at the forefront of her field by regularly attending cosmetic medical conferences to master the latest techniques and technologies. Her training includes working alongside leading experts throughout North America.

Committed to creating effective yet clean skincare solutions, Dr. Pearlman developed The PearlMD Skin CareRx line, which delivers pharmaceutical-grade active ingredients without potentially harmful chemicals, designed to lighten, brighten, and revitalize the skin.

JJ Virgin is a triple-board certified nutrition expert, Fitness Hall of Famer, and passionate advocate for the healing power of nutrition. As the founder of Mindshare Collaborative—the most influential professional community in health—she has helped launch countless New York Times bestsellers and seven-figure brands.

A prominent media personality, JJ co-hosted TLC's Freaky Eaters, served as Dr. Phil's nutrition expert, and has appeared on PBS, Dr. Oz, and The TODAY Show. She's authored four NY Times bestsellers including The Virgin Diet and Warrior Mom, which shares lessons from fighting for her son's life.

JJ has built two multimillion-dollar businesses, speaks to audiences of 10,000+, and hosts the popular Well Beyond 40 podcast with over 22 million downloads. As a 3x Inc. 5000 Founder, she continues to transform lives through her evidence-based approach to nutrition, fitness, and longevity.

Dr. Angela D. Mazza, DO, is triple board-certified in endocrinology, internal medicine, and anti-aging and regenerative medicine. With her impressive credentials (ABAARM, FAAMFM, ECNU, CDE), she specializes in diagnosing and treating conditions such as thyroid disease and hormonal imbalances. As a Doctor of Osteopathy, Dr. Mazza takes a holistic approach to healthcare, integrating cutting-edge medical findings with personalized lifestyle modifications to address each patient's unique needs.

A distinguished thyroid specialist with ECNU certification, Dr. Mazza specializes in radiofrequency ablation (RFA) procedures for thyroid nodules. What sets her practice apart is her commitment to treating the whole person rather than just the condition. Dr. Mazza and her dedicated team work collaboratively with patients, ensuring comprehensive care that addresses both the medical aspects of their conditions and their overall wellbeing.

Dr. Florence Comite, MD is a clinician-scientist, endocrinologist, and the leading expert in the fields of healthy longevity and precision medicine. Her international reputation stems from her innovative approach to leveraging proprietary clinical and wearable data in her private clinical and virtual practice to detect, predict, and reverse biological aging, while optimizing health and vitality.

As a graduate of Yale School of Medicine, Dr. Comite served as a faculty member for twenty-five years with a distinguished triple appointment in Endocrinology (Internal Medicine and Pediatrics) and Reproductive Endocrinology (Gynecology and Andrology). During her career, she trained at the National Institutes of Health and founded Women's Health at Yale, establishing the nation's first women-only clinic.

In 2005, Dr. Comite founded the Comite Center for Precision Medicine & Healthy Longevity in New York City, where she developed the groundbreaking Nof1™ clinical process, treating each patient as a single subject clinical trial. The Center's success has led to expansions in Palo Alto and Miami Beach. Her innovative approach has attracted a global clientele, including forward-thinking physicians, industry leaders, and entrepreneurs, each receiving personalized healthcare interventions tailored to their individual needs.

Her commitment to advancing medical science is evident through her extensive research and publications in prestigious journals such as the New England Journal of Medicine, JAMA: The Journal of the American Medical Association, and the Journal of the Endocrine Society. Dr. Comite's pioneering research spans across children, women, and men, recognizing the critical role of the entire system in aging and disease.

In 2013, she authored the bestselling book "Keep It Up: The Power of Precision Medicine to Conquer Low T and Revitalize Your Life," focusing on androgen deficiency and vitality in aging men. Her next book, "Invincible: Eliminate the Disorders of Aging for a Healthy, Long Life," will be published by Little Brown, Spark in Spring 2026. Through her startup Groq Health, Dr. Comite is scaling her precise methodology of precision medicine to a digital clinic delivered virtually.

As a sought-after keynote speaker, Dr. Comite continues to captivate audiences worldwide, sharing her expertise and vision for the future of precision medicine and healthy longevity.