Dr Sarah Berry is a researcher and senior lecturer in nutritional science at King's College London. Her research interests relate to the influence of dietary components on markers of cardiovascular disease risk; with a particular focus on the influence of food and fat structure on postprandial metabolism.

Dr. Berry has been the academic leader for more than 30 human nutrition studies in cardio-metabolic health. Her research also focuses on the influence of manipulation of food structure and subsequent effects on lipid and carbohydrate bioaccessibility and changes in postprandial metabolism.

Sarah is also the lead nutritional scientist on an ongoing series of postprandial metabolic studies, assessing the genetic, metabolic, metagenomic, and meal-dependent effects on postprandial metabolic responses in >1,200 individuals in the UK and US.

Show notes available at sigmanutrition.com/episode361

Nick Hiebert writes about nutrition science on his site The Nutrivore, as well as exclusive, comprehnsive posts on his Patreon page. He is the creator of the "Nutrient Density Cheat Sheet", a nutrition ranking tool for hundreds of whole foods.

Nick has a deep interest in a host of nutrition science topics, from nutrient density to saturated fat & cardiovascular disease. He does a lot of deep analysis of raw data and has published some independent meta-analyses on his site.

Show notes can be found at sigmanutrition.com/episode360

In this episode Danny and Alan discuss the common misunderstandings and misrepresentations of the energy balance equation, leading to problematic debates over the validity of 'calories in, calories out'. Today's Topic in Focus: Calories In, Calories Out [02:15] "I Have a Question!" [60:17] Quack Asylum [70:20] Random Recommendations [76:20] SHOW NOTES: sigmanutrition.com/episode359

In this episode Danny and Alan discuss the health impacts of coffee consumption, including long-term protective influence on disease risk, acute impacts, optimal dosages, genetic differences in metabolism and the influence of the bioactive compounds in coffee.

Today's Topic in Focus: [01:50]

"I Have a Question!" [68:18]

Quack Asylum [71:03]

Random Recommendations [81:50]

Show Notes: sigmanutrition.com/episode358

Dr. Nicky Keay is a medical doctor (MB BChir, MRCP) with specific training in endocrinology. She has published related to female athlete hormone profiling, energy availability, and relative energy deficiency in sport (RED-S).

As a Research Fellow at St Thomas' Hospital, she was part of the international medical team which developed an anti-doping test for growth hormone.

Dr. Keay studied medicine at Cambridge University, gained membership of the Royal College of Physicians, and trained in endocrinology.

Dr. Keay is currently an Honoray Fellow at Durham Universty in the Department of Sport and Exercise Sciences.

Show notes at sigmanutrition.com/episode357

Dr. Hana Kahleova is the director of clinical research at the Physicians Committee and directs research testing the effect a plant-based diet has on metabolism, insulin function, fitness, and mental health, as well as studying the impact meal timing and meal frequency have on metabolism and body weight.

Dr. Kahleova earned her doctorate in nutrition and diabetes and her medical degree from Charles University in Prague, Czech Republic. As a postdoctoral research fellow at Loma Linda University in California, Dr. Kahleova analyzed data from 50,000 Adventist Health Study-2 participants. She analyzed data on meal frequency and timing in relationship to changes in body weight.

Show notes at: sigmanutrition.com/episode356

Danny & Alan discuss a recent paper on time-restricted eating that has been inaccurately interpreted by some as a "disproval" of TRE as an intervention. In this episode, the aim is to provide some context to the situation.

There are also three listener questions, and another person/claim is brought into the quack asylum!

Today's Topic in Focus: Time-Restricted Eating [05:14]

"I Have a Question!" [57:27]

Quack Asylum [73:35]

Random Recommendations [86:05]

SHOW NOTES: sigmanutrition.com/episode355

Danny & Alan discuss issues with using and interpreting meta-analyses in nutritional science, they answer a question about methods of reheating food, and they highlight a recent paper published by quacks that experts have termed a "deception".

Today's Topic in Focus [08:50]

"I Have a Question!" [53:35]

Quack Asylum [59:32]

Something Random [66:42]

Show notes: https://sigmanutrition.com/episode354

Dr. James Hébert is a nutritional and cancer epidemiologist, currently a distinguished Professor at the University of South Carolina. Dr. Hébert's professional focus for the past several years has been on developing and refining the Dietary Inflammatory Index™ (DII®), which has now been established as an effective research tool.

Dr. Hébert is also a Professor in the Department of Epidemiology and Biostatistics, a Professor of Epidemiology at the Medical University of South Carolina, a Professor of Community Medicine and Epidemiology at the University of South Carolina, School of Medicine, and the Director of the Cancer Prevention and Control Program.

Dr. Hébert obtained his ScD (Doctor of Science) in nutritional epidemiology from Harvard University in 1984.

Show Notes: sigmanutrition.com/episode353

Danny and Alan take a look at the evidence on weight loss maintenance, answer a question about ApoE4, and admit another nonsensical claim into the quack asylum. In this episode:

[02:56] Today's Topic in Focus: Weight Regain vs Weight Loss Maintenance

[58:56] I Have a Question!: "How does the ApoE4 allele affect lipid metabolism? And how should someone structure their diet around having one or both alleles due to it resulting in higher LDL-C than someone without the gene?"

[63:09] Quack Asylum: Irish doctors gives nonsensical and harmful nutrition recommendations.

[76:35] Random Recommendations

Show notes: sigmanutrition.com/episode352