The Dr. Brighten Show

Sjogrens Syndrome and Treatment: What Women Need to Know | Dr. Kara Wada


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In this conversation, Dr. Jolene Brighten and quadruple–board-certified allergist & immunologist Dr. Kara Wada unpack why sjogren's disease is widely under-recognized, how “perfectionist” health habits can backfire into autoimmune flares, and exactly how to think about sjogren's treatment, testing, microbiome/barrier health, dysautonomia, POTS, MCAS, and smarter allergy therapies.

A sjogren’s test typically includes autoantibodies (SSA/SSB), but these are only ~60–70% positive, so diagnosis relies on the full picture: history, eye/dental findings, sometimes biopsy. Importantly, Sjögren’s carries a 5–10% lifetime risk of non-Hodgkin lymphoma, so persistent lymph nodes deserve prompt evaluation. Because labs can be “normal” while life isn’t, bring concrete examples of how symptoms limit your day, and ask for a plan that fits your stage of life (puberty, pregnancy, perimenopause).


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Links & Resources Mentioned in This Episode:

  • Sjögren’s Foundation (patient education & resources): https://www.sjogrens.org
  • Gut Hormone Connection Episode: https://drbrighten.com/podcasts/gut-health-probiotics/
  • Therapies discussed: Allergy shots; Sublingual immunotherapy (tablets/drops) and Intralymphatic immunotherapy (ILIT)
  • Medications referenced (discuss with your clinician): Hydroxychloroquine (Plaquenil); H1 antihistamines (e.g., loratadine, cetirizine); H2 blocker (famotidine); caution with diphenhydramine (Benadryl)
  • Research context named in the episode: LEAP trial (early oral peanut introduction): https://www.nejm.org/doi/full/10.1056/NEJMoa1414850 


    Follow Dr. Kara Wada:

    💻 Website: https://drkarawada.com 

    📸  Instagram: https://www.instagram.com/immuneconfidentmd/

    ⭕ YouTube: https://www.youtube.com/@drkarawada 

    👩🏻‍⚕️Follow Dr. Jolene Brighten:

    💻 Website: https://www.drbrighten.com

    📸  Instagram: https://www.instagram.com/drjolenebrighten

    🎥 TikTok: https://www.tiktok.com/@drjolenebrighten

    🧵Threads: https://www.threads.net/@drjolenebrighten

    🌟 Grab my free hormone friendly recipes here! https://drbrighten.com/hormonekit/

    🎧 Subscribe to the Podcast: 

    Apple: https://podcasts.apple.com/us/podcast/the-dr-brighten-show/id1786362161

    Spotify: https://open.spotify.com/show/5VWcYWJFzi3OnwidT25IXi?si=481df20ef0a6417

     YouTube: https://www.youtube.com/@drjolenebrighten

    👉 If you found this episode valuable, drop a comment below to tell us what you loved most, and share it with a friend! Let’s spread the knowledge. 💬✨

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    The Dr. Brighten ShowBy Dr. Jolene Brighten

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