The Joe Cohen Show

SNPit #01 | The MTHFR Debate: Overhyped or Underestimated?


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Welcome to SNPits, a new, short-form podcast series that takes you on a deep dive into specific genes, unraveling the science behind them and their impact on health. 

In this episode, we tackle the MTHFR gene and its rise to fame.

We explore how 'typos' in our genes, known as SNPs, influence our health, and dive into the debate surrounding one of the most studied genes in the world. 

Is the MTHFR gene truly a culprit in conditions like heart disease and chronic fatigue, or is it a scapegoat? 

Join us as we decode the science, bust some myths, and take a closer look at how our genes really affect our health. Whether you're a genetics guru or new to the subject, this episode offers an insightful and entertaining look at the complexity of our genetic code. 

If you're interested in learning more about how your DNA and genetics affect your health, you can:

- Check out SelfDecode: ⁠https://selfdecode.com/⁠

- Join Joe’s online community: ⁠https://thejoecohenshow.com/⁠ 

Links:

Some studies found a 35-70% reduction in enzyme activity [R], and links between MTHFR variants, higher homocysteine, and:

  • Heart disease and stroke [R, R]

  • Fertility and pregnancy issues [R, R, R, R, R, R]

  • Mental health issues [R]

  • Migraines with aura [R, R]

  • Some studies found no evidence for these links. Some even found the opposite results. In one study, MTHFR variants were linked to a lower risk of death from heart disease [R, R, R, R, R]

    ...more
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