The Adam and Dr. Drew Show

Introducing HRT for menopause: is it safe? from ZOE Science & Nutrition.

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Menopause is a time of significant hormonal changes which can lead to a range of symptoms that can severely impact quality of life for many women. So, a drug that promises to reduce these symptoms is incredibly welcome, but it has been steeped in controversy.

HRT (Hormone replacement therapy) has been widely debated, with conflicting information about its effectiveness, with some suggesting HRT is outright dangerous. In fact, a massive study twenty years ago linked it to an increased risk of breast cancer. As a result, the numbers of women taking HRT plummeted. So should HRT be avoided at all costs? 

In today’s episode, Jonathan is joined by the author of that very study and esteemed Professor JoAnn Manson, alongside Dr. Sarah Berry to explore the science behind HRT.

With the help of ZOE regular Dr. Sarah Berry, they delve into the science behind HRT, empowering listeners to make informed decisions about treatment for symptoms of the menopause.

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Timecodes:

00:00 Introduction

00:12 Jonathan's introduction

01:33 Quick Fire Questions

03:27 What is the menopause?

04:10 What is the perimenopause?

05:46 What is the state of the current conversation on the menopause?

07:13 Should women seek help about the menopause?

07:58 Why do some women have symptoms and others not?

09:15 Yougov and ZOE study results on the menopause

11:35 Why is the menopause getting more attention now?

13:39 Should we be taking these symptoms seriously?

17:10 What else can be done asides from HRT?

18:49 Studies on the relationship between diet and menopause symptoms

19:35 What can help alleviate symptoms?

21:23 Are there any specific foods that can help improve symptoms?

23:37 Are menopause specific supplements effective?

24:50 How does HRT work?

26:26 Is HRT just oestrogen?

30:59 Does testosterone have a use for menopause?

31:58 What is the controversy behind HRT?

35:56 What's the latest advice and health risks?

38:11 When should you stop hormone therapy?

40:43 Do symptoms persist when you come off of hormone therapy?

42:00 How long does HRT take to start working?

43:07 How does HRT affect weight management?

45:15 Summary

48:04 Goodbyes

48:25 Outro

Check the trials mentioned in today’s episode: 

MsFlash: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731298/

ZOE Menopause Study: https://joinzoe.com/learn/menopause-metabolism-study

PEPI Trial: https://pubmed.ncbi.nlm.nih.gov/7807658/

Follow Sarah: https://twitter.com/saraheeberry

Follow ZOE on Instagram: https://www.instagram.com/zoe/

Episode transcripts are available here.

Is there a nutrition topic you’d like us to cover? Get in touch and we’ll do our best to cover it.

DISCLAIMER: Please note, this is an independent podcast episode not affiliated with, endorsed by, or produced in conjunction with the host podcast feed or any of its media entities. The views and opinions expressed in this episode are solely those of the creators and guests. For any concerns, please reach out to [email protected].

Introducing Transformations in AI: Why Foundation Models Are the Future from Smart Talks with IBM.

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Major breakthroughs in artificial intelligence research often reshape the design and utility of AI in both business and society. In this episode of Smart Talks with IBM, Malcolm Gladwell and Jacob Goldstein explore the conceptual underpinnings of modern AI with Dr. David Cox, VP of AI Models at IBM Research. They talk foundation models, self-supervised machine learning, and the practical applications of AI and data platforms like watsonx in business and technology.

Visit us at: https://www.ibm.com/smarttalks/

Learn more about watsonx: https://www.ibm.com/watsonx

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DISCLAIMER: Please note, this is an independent podcast episode not affiliated with, endorsed by, or produced in conjunction with the host podcast feed or any of its media entities. The views and opinions expressed in this episode are solely those of the creators and guests. For any concerns, please reach out to [email protected].

Introducing Are We Being Ruled By A Shadow Government? | Shane Smith Has Questions from Shane Smith Has Questions.

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Shane Smith and author Peter Dale Scott, who popularized the term the Deep State four decades ago, on how it combines government agencies, the military, and organized crime. Scott discusses everything from recent Trump assassination attempts to historical deep events like the Bay of Pigs, the CIA and Mafia attempting to assassinate Fidel Castro, the Kennedy assassination, and Watergate. They get into the CIA’s involvement in the d**g trade, from Burma to Afghanistan, and its links to American cities during the Vietnam War. They get into how continuity of government plans, originally developed during the Cold War, were implemented on 9/11 and how that contributed to the creation of post-9/11 policies like the Patriot Act. They cover how Oligarchs in the Ukraine could be manipulating events to maintain financial control, especially regarding the ongoing conflict with Russia, and how economic interests are at play in both the war and U.S. political dynamics. And it’s funny!

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DISCLAIMER: Please note, this is an independent podcast episode not affiliated with, endorsed by, or produced in conjunction with the host podcast feed or any of its media entities. The views and opinions expressed in this episode are solely those of the creators and guests. For any concerns, please reach out to [email protected].

Introducing Do vitamin D supplements work? | Prof. Tim Spector and Dr. Federica Amati from ZOE Science & Nutrition.

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Vitamin D is the world’s favorite supplement. Governments around the world recommend people take the supplement for at least six months out of the year. But do we really need these pills? Do they even work? And could they actually be harming us?

In this episode, two ZOE scientists - Professor Tim Spector and Dr Federica Amati reveal the truth about vitamin D.

Tim is scientific co-founder of ZOE and professor of epidemiology at King’s College London. Federica is head nutritionist at ZOE and author of the Sunday Times bestseller ‘Every Body Should Know This’.

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*Naturally high in copper which contributes to normal energy yielding metabolism and the normal function of the immune system

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Timecodes:

00:00 The sunshine vitamin

01:50 Quickfire questions

04:05 What is vitamin D?

07:12 Is sunlight the best source of vitamin D?

09:40 Does vitamin D keep my bones strong?

15:34 Are vitamin D levels a marker of good health?

20:00 What counts as normal levels of vitamin D? 

24:42 Supplement controversy

29:10 Do calcium supplements help bones?

31:29 Can I take too much vitamin D?

37:50 Could vitamin D prevent these health conditions?

42:54 Tim’s sunscreen controversy

46:46 Vitamin D and immunity

Books by our ZOE Scientists:

Mentioned in today’s episode:

Other ZOE Science & Nutrition episodes to try:

Have feedback or a topic you'd like us to cover? Let us know here.

Episode transcripts are available here.

DISCLAIMER: Please note, this is an independent podcast episode not affiliated with, endorsed by, or produced in conjunction with the host podcast feed or any of its media entities. The views and opinions expressed in this episode are solely those of the creators and guests. For any concerns, please reach out to [email protected].

Introducing What to eat to avoid osteoporosis from ZOE Science & Nutrition.

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Every 12 years, our skeletons undergo a complete transformation.

Prof. Tim Spector and Prof. Cyrus Cooper discuss how to avoid Osteoporosis, a condition where bones become fragile, significantly increases the risk of fractures from minor incidents, often without any noticeable symptoms. Worldwide, it affects one in three women and one in five men over fifty, leading to pain, potential disability and loss of independence.

In today’s episode, Jonathan, Tim and Cyrus ask the question: How can understanding osteoporosis and implementing targeted lifestyle changes enhance bone health and reduce the risk of fractures?

Cyrus Cooper is a Professor of Rheumatology at the University of Southampton, where he is also the Director of the MRC Lifecourse Epidemiology Unit and Vice-Dean of Medicine. In addition, he’s a Professor of Musculoskeletal Science at the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences at the University of Oxford.

Tim Spector is one of the world’s top 100 most-cited scientists, a professor of epidemiology, and scientific Co-Founder at ZOE. Tim trained originally in rheumatology and epidemiology. 

🌱 Try our new plant based wholefood supplement - Daily30+

*Naturally high in copper which contributes to normal energy yielding metabolism and the normal function of the immune system

Learn how your body responds to food 👉 zoe.com/podcast for 10% off

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Timecodes

00:00 Introduction

01:21 Quickfire questions

03:08 What is osteoporosis?

06:10 Why might our bones become more fragile as we age?

08:10 Your skeleton renews itself all the time

10:30 Does menopause cause osteoporosis?

12:48 What's it like living with osteoporosis?

15:16 How common is osteoporosis in males?

16:04 What are the symptoms of osteoporosis and at what age should you get checked?

21:40 Some chilling statistics about osteoporosis

23:10 Common myths about the effects of calcium and vitamin D on osteoporosis

27:50 What is the latest science on vitamin D supplementation?

34:10 Can vitamin D and calcium ensure children’s bone density is healthy?

34:55 Osteoporosis treatment options, including new drugs    

37:20 The impacts of HRT on bone density

39:30 What are the downsides to some of these treatments?

43:00 Does physical activity help to prevent fractures?

44:30 Lifestyle impacts: diet and nutrition

49:40 Can exercise make your bones stronger?

55:20 Ideal exercises to prevent osteoporosis

57:10 Cyrus and Tim’s top 3 actions to improve bone health

59:10 Summary

Mentioned in today's episode:

Relevant studies:

Books:

Have feedback or a topic you'd like us to cover? Let us know here

Episode transcripts are available here.

DISCLAIMER: Please note, this is an independent podcast episode not affiliated with, endorsed by, or produced in conjunction with the host podcast feed or any of its media entities. The views and opinions expressed in this episode are solely those of the creators and guests. For any concerns, please reach out to [email protected].