The Biology of Trauma® With Dr. Aimie

The Biology Behind It: Do Babies Who Cry It Out Get Anxiety and Addiction Later in Life?


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Ever wondered why some adults struggle with anxiety, depression, or feeling overwhelmed even in safe situations? The answer might trace back to something as common as being left to cry it out as a baby.

In this mini episode, Dr. Aimie dives deep into the biology behind how early childhood experiences, including seemingly normal parenting practices, can program our immune cells for danger and create lasting brain inflammation, explaining the long-term effects of crying it out on mental health.

Responding to a listener's question about brain inflammation in babies, Dr. Aimie reveals what's actually happening inside tiny brains when they're left to cry it out, and how this creates the anxiety and depression we see later in life. You'll discover how your body's own biology might be perpetuating nervous system dysregulation from experiences you don't even remember.

In this episode, you'll learn:

  • How stress in early childhood creates "primed" microglia in the brain
  • Why these primed immune cells can trigger brain inflammation, anxiety, and depression later in life
  • The difference between stress and trauma (and why babies are especially vulnerable)
  • Why common experiences like birth trauma, NICU stays, and "crying it out" can rewire your stress response for life
  • The link between microglia activation, brain fog, decision fatigue, and emotional overwhelm
  • Practical steps for healing brain inflammation from childhood trauma and calming your nervous system

Whether you're working on your own healing or helping others who still feel stuck after therapy, this episode will help you understand why your body can still feel anxious and overwhelmed even when you know you're safe. Plus get simple tools to help your brain's immune system begin to heal!

🎧 Want the full story? Listen to Episode 132 with Dr. Darcia Narvaez to discover more common parenting practices that actually create a biology of trauma and lead to anxiety and addiction later in life. If you would like to watch the video version of this episode, head here to see the slides Dr. Aimie references in the episode.

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The Biology of Trauma® With Dr. AimieBy Dr. Aimie Apigian

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