The Dr. Geo Prostate Podcast

The most dangerous thing about peptides may not be the peptide itself—it may be what's actually inside the vial.

Peptides are everywhere. From BPC-157 for injury recovery to anti-aging treatments, hormone optimization, and the growing popularity of GLP-1 medications, these compounds are generating enormous excitement. But which peptides are backed by science, which are still experimental, and what happens when people buy injectable products online without medical supervision?

Dr. James LaValle, clinical pharmacist, board-certified clinical nutritionist, and longtime educator in precision health and longevity medicine, joins Dr. Geo to separate the science from the hype. Drawing on more than four decades in pharmacy and his involvement in FDA advisory discussions, LaValle explains how peptides work, why compounding regulations matter, and what patients should understand before considering these treatments.

The conversation takes an especially important turn for men with prostate cancer, as Dr. Geo raises concerns about BPC-157, blood vessel formation, and the unanswered questions surrounding peptide use in patients with cancer.

In this episode, you’ll learn...

🟠 What peptides actually are, how they work in the body, and why not all peptides are created equal.

🟠 Why BPC-157 is generating excitement for injury recovery and gut health—and the unanswered safety questions for men with prostate cancer.

🟠 What the FDA's peptide regulations and compounding discussions mean for patients, and why an advisory committee recommendation is not the same as FDA approval.

🟠 How to recognize potentially unsafe peptides sold online, understand the risks of unregulated injections, and avoid the dangers of peptide overuse.

📚 Chapters

00:00 Are Peptides Really Safe?

03:00 What Are Peptides?

08:00 FDA-Approved vs. Experimental Peptides

10:00 Compounding Pharmacies Explained

13:00 The Dangers of Online Peptides

16:00 FDA Regulations and Peptide Access

19:00 GLP-1 Medications and Proper Dosing

24:00 BPC-157 for Injury Recovery

27:00 BPC-157 and Prostate Cancer Concerns

30:00 TB-500 and Immune Health

35:00 MOTS-c and Mitochondrial Aging

38:00 Epitalon, Sleep, and Growth Hormone

43:00 DSIP, Semax, and Brain Health

47:00 Oral vs. Injectable Peptides

51:00 How to Identify Unsafe Peptides

55:00 Long-Term Risks and Peptide Overuse

59:00 Dr. LaValle's Work and Resources

Peptides may hold exciting possibilities for the future of medicine. But promising science is not the same as proven safety—and knowing the difference could protect your health.

📕 Get Dr. Geo’s Free Ebook- A Guide to Improve Prostate Problems Naturally https://bit.ly/DRGEOFreeEbook

🎯Subscribe to the Dr. Geo Prostate Podcast and visit https://drgeo.com for evidence-informed prostate health education and the Rx3 Thursdays newsletter.

🎙️ GUEST – Links related to the podcast:

Dr. James LaValle

Website: https://jimlavalle.com

Instagram: @therealjimlavalle

📌 Thank You To Our Sponsors

Sponsored by PathRight Medical. RestoreXL® provides a focused option for restoring lost penile length or limiting loss of erectile function following prostatectomy.

For more information on RestoreXL: https://bit.ly/3VWiC9L.

📌 Dr. Geo’s Social Media and Websites

Instagram: https://bit.ly/DRGEO-INSTA-YT

Facebook: https://bit.ly/POD-FB-DrGeo

LinkedIn: https://bit.ly/DRGEO-LINKEDIN-YT

Website: https://bit.ly/43khht0

XY Wellness – Prostate Health Supplements: https://bit.ly/3uJPC7Z

Mr. Happy – Supplements for Men: https://bit.ly/3RJMX6O

📣 Hashtags

#DrGeoProstatePodcast #Peptides #BPC157 #AntiAging #Longevity #ProstateHealth #MensHealth #FDA #IntegrativeMedicine

⚠️ Disclaimer

This podcast is for educational purposes only and not medical advice. The views expressed are Dr. Geo’s and not those of his employer(s) or affiliated organizations. Use of this content is at your own risk. Geovanni Espinosa, N.D., assumes no liability for direct or indirect consequences, including economic loss, injury, illness, or death.

The biggest mistake after prostate cancer treatment may be waiting for erections to “come back” on their own.

Dr. John Mulhall of Memorial Sloan Kettering has spent three decades in sexual medicine, sees roughly 600 prostatectomy patients a year, and served as a senior author on sexual-medicine guidelines. His central message: recovery is a race to protect erectile tissue while nerves heal. After prostatectomy, erection nerves can remain functionally “asleep” for months. During that window, reduced blood flow, oxygenation and stretch can allow penile smooth muscle to deteriorate and be replaced by collagen-rich scar tissue. Radiation follows a different pattern: function may look preserved at first, then decline over two to three years as vascular injury develops.

In this episode, you’ll learn...

• Why penile rehabilitation is about preserving tissue, not simply taking a daily pill.
• How surgery, radiation, and ADT disrupt erections through different biological pathways.
• Why sleep apnea, diabetes, and very low testosterone can reduce recovery.
• How reducing performance pressure can rebuild sexual confidence.

📚 Chapters

00:00 Sex Recovery Starts Early

05:28 Why Erections Fail

07:36 Radiation And ADT Effects

11:07 Collagenization Explained

12:39 Modern Penile Rehab Plan

16:14 Choosing A Prostate Surgeon

19:49 Orgasms After Prostatectomy

21:38 Erection Recovery Timeline

24:19 Confidence And Intimacy

34:34 Injection Safety Standards

40:48 Testosterone Before Treatment

45:24 ADT Risks and PSA Monitoring

56:32 When to Consider Implants

59:37 Choosing the Right PDE5 Pill

01:01:23 Trials and Where to Find John

This is the conversation men need before treatment—not months after sexual function has already changed.

Dr. Mulhall X handle@saveyoursexlife

Website: Dr. John Mulhall - MSKCC

📕 Get Dr. Geo’s Free Ebook- A Guide to Improve Prostate Problems Naturally https://bit.ly/DRGEOFreeEbook

📌Thank You To Our Sponsors

Sponsored by PathRight Medical. This episode's guest, Dr. Landon Trost, is the majority owner of PathRight Medical, manufacturer of RestoreX® and RestoreXL®. Dr. Geo Media retains editorial control over the interview and its independent clinical content.

Find the Right Device for You linked to https://bit.ly/3VnIsU0.

___________________________________

💪 Exclusive Membership

Want deeper insights? Join The Dr. Geo Prostate Podcast Exclusive Membership for curated transcripts, detailed show notes, expert resources, and member perks. → https://drgeo.com/membership

___________________________________

📌 Dr. Geo’s Social Media and Websites

📺 YouTube → Dr. Geo Prostate Podcast — https://www.youtube.com/@DrGeoProstatePodcast

🎧 All Episodes → Captivate.fm Archive — https://dr-geo-prostate-podcast.captivate.fm

📸 Instagram → https://bit.ly/DRGEO-INSTA-YT

📘 Facebook → https://bit.ly/POD-FB-DrGeo

💼 LinkedIn → https://bit.ly/DRGEO-LINKEDIN-YT

🛒 Supplements → XY Wellness https://bit.ly/3uJPC7Z | Mr. Happy https://bit.ly/3TE7tWE

🌐 DrGeo.com Website → https://bit.ly/43khht0

📣 Hashtags

#DrGeoProstatePodcast #ProstateHealth #ProstateCancer #MensHealth #IntegrativeUrology #Urology

___________________________________

⚠️ Disclaimer

This podcast is for educational purposes only and not medical advice. The views expressed are Dr. Geo’s and not those of his employer(s) or affiliated organizations. Use of this content is at your own risk. Geovanni Espinosa, N.D., assumes no liability for direct or indirect consequences, including economic loss, injury, illness, or death.

What causes Peyronie’s disease? Can penile curvature be reversed without surgery? And what actually works to restore lost penile length?

In this episode of the Dr. Geo Prostate Podcast, Dr. Geo Espinosa welcomes Dr. Landon Trost, former Chief of Andrology at Mayo Clinic and a leading researcher in Peyronie’s disease and men's sexual health.

Together, they separate science from misinformation and explore the latest research on Peyronie’s disease, Xiaflex injections, RestoreX penile traction therapy, and why early intervention may make a significant difference.

Dr. Trost also shares the research behind combining Xiaflex with RestoreX, why some commonly recommended treatments lack convincing evidence, and what men should understand before considering surgery.

Whether you've recently noticed penile curvature, are experiencing lost length, or are exploring treatment options, this conversation offers valuable insights to help you make more informed decisions about your sexual health.

• What causes Peyronie’s disease and how genetics may contribute.
• The connection between Peyronie’s disease and Dupuytren’s contracture.
• Why popular remedies like pentoxifylline, castor oil, and manual stretching may not deliver the results men expect.
• When penile curvature requires treatment and why early intervention matters.
• How erectile quality and penile trauma may influence risk.
• How Peyronie’s disease is diagnosed.
• The science behind Xiaflex injections and RestoreX traction therapy.
• What clinical trials reveal about restoring lost penile length.
• How often RestoreX was used in clinical studies and how long improvements may last.
• The potential side effects of Xiaflex and when surgery may be considered.
• The psychological impact of Peyronie’s disease and the future of treatment.

📚 Chapters

00:00 Introduction: Can Peyronie’s Disease Be Reversed?

01:40 Meet Dr. Landon Trost

06:30 What Causes Peyronie’s Disease?

07:50 Genetics and Dupuytren’s Contracture 09:15 Common Myths and Ineffective Treatments

15:20 When Does Penile Curvature Need Treatment?

16:50 Why Early Treatment Matters

20:00 Can You Prevent Peyronie’s Disease?

25:30 How Peyronie’s Disease Is Diagnosed

28:00 Early Treatment Options

31:00 Traction Therapy and Restoring Lost Length

32:30 Why Xiaflex + RestoreX Work Better Together

38:15 The Science Behind RestoreX

41:15 How Often Should You Use RestoreX?

🎙️ GUEST

Dr. Landon Trost Clinic - https://malefertilityandpeyroniesclinic.com/about/

Peyronies.com - https://malefertilityandpeyroniesclinic.com/peyronies/

Goniometer - https://en.wikipedia.org/wiki/Goniometer

📕 Get Dr. Geo’s Free Ebook- A Guide to Improve Prostate Problems Naturally https://bit.ly/DRGEOFreeEbook

📌Thank You To Our Sponsors

Sponsored by PathRight Medical. This episode's guest, Dr. Landon Trost, is the majority owner of PathRight Medical, manufacturer of RestoreX® and RestoreXL®. Dr. Geo Media retains editorial control over the interview and its independent clinical content.

Find the Right Device for You linked to https://bit.ly/3VnIsU0.

📌 Dr. Geo’s Social Media and Websites

Instagram: https://bit.ly/DRGEO-INSTA-YT

Facebook: https://bit.ly/POD-FB-DrGeo

LinkedIn: https://bit.ly/DRGEO-LINKEDIN-YT

Website: https://bit.ly/43khht0

XY Wellness- Prostate Health Supplements - https://bit.ly/3uJPC7Z

Mr. Happy- Supplements for Men- https://bit.ly/3RJMX6O

___________________________________

Want deeper insights? Join The Dr. Geo Prostate Podcast Exclusive Membership for curated transcripts, detailed show notes, expert resources, and member perks. → https://drgeo.com/membership

___________________________________

📺 YouTube → Dr. Geo Prostate Podcast — https://www.youtube.com/@DrGeoProstatePodcast

🎧 All Episodes → Captivate.fm Archive — https://dr-geo-prostate-podcast.captivate.fm

📸 Instagram → https://bit.ly/DRGEO-INSTA-YT

📘 Facebook → https://bit.ly/POD-FB-DrGeo

💼 LinkedIn → https://bit.ly/DRGEO-LINKEDIN-YT

🛒 Supplements → XY Wellness https://bit.ly/3uJPC7Z | Mr. Happy https://bit.ly/3TE7tWE

🌐 DrGeo.com Website → https://bit.ly/43khht0

___________________________________

#DrGeoProstatePodcast #ProstateHealth #ProstateCancer #MensHealth #IntegrativeUrology #Urology

This podcast is for educational purposes only and not medical advice. The views expressed are Dr. Geo’s and not those of his employer(s) or affiliated organizations. Use of this content is at your own risk. Geovanni Espinosa, N.D., assumes no liability for direct or indirect consequences, including economic loss, injury, illness, or death.

Before prostate surgery, there are 3 questions you should ask your surgeon—and “How many surgeries have you done?” isn’t enough.

In this episode of The Dr. Geo Prostate Podcast, Dr. Geo sits down with renowned prostate cancer surgeon Dr. Jim Hu, Ronald P. Lynch Professor of Urologic Oncology at Weill Cornell Medicine, Vice Chair of Clinical Research, and Director of the LeFrak Center for Robotic Surgery.

The conversation starts where many prostate cancer journeys begin: an elevated PSA.

Do you really need a biopsy? Should you get an MRI first? What about PSA density, the 4Kscore, or newer urine tests? And if a biopsy is necessary, should you choose transperineal instead of transrectal biopsy?

Dr. Hu explains why he now favors the transperineal approach and discusses findings from the PREVENT and UK TRANSLATE trials, including infection risk, antibiotic use, cancer detection, pain, and the learning curve physicians face when adopting the procedure.

Then the conversation turns to one of the biggest decisions a man with prostate cancer may ever make:

Surgery or radiation?

And if you choose surgery, how do you know whether your surgeon is actually good?

Dr. Hu explains why simply asking how many prostatectomies a surgeon has performed may not tell you what you really need to know. Instead, patients should be asking whether their surgeon actually tracks urinary continence and erectile-function outcomes.

Because two surgeons can perform the same “robotic prostatectomy” very differently—and those differences may matter to your quality of life.

In this episode, you’ll learn:

• What an elevated PSA really means—and what may come before biopsy

• How MRI, PSA density, 4Kscore, and urine biomarkers can help guide decisions

• Why Dr. Hu favors transperineal prostate biopsy

• What the PREVENT and TRANSLATE trials tell us about prostate biopsy

• Why avoiding antibiotics may be another advantage of transperineal biopsy

• The learning curve patients should consider when choosing who performs their biopsy

• How to think about prostate surgery vs. radiation

• Why robotic technology doesn’t automatically mean better surgical outcomes

• Why surgical volume alone may not predict continence or erectile-function recovery

• The questions to ask before choosing a prostate cancer surgeon

• Why surgeons should track their own patient-reported outcomes

• How surgical technique, nerve handling, and cautery may affect recovery

• Where active surveillance and focal therapy may—or may not—fit

• Why treatment choice matters if prostate cancer eventually returns

• What patients should understand about salvage prostatectomy after radiation or focal therapy

If you’ve recently been diagnosed with prostate cancer—or you’re trying to decide whether to have a biopsy, surgery, radiation, focal therapy, or active surveillance—watch this conversation before making a decision you can’t easily take back.

Chapters

⏱️ KEY TIMESTAMPS

00:00 – The prostate cancer decisions you can’t easily take back

08:00 – Elevated PSA: Do you really need a biopsy?

12:00 – How MRI can help some men avoid biopsy

16:00 – PSA density, MRI & deciding whether to biopsy

17:00 – Transperineal vs. transrectal prostate biopsy

19:00 – PREVENT & TRANSLATE studies: infection and cancer detection

22:00 – The learning curve for transperineal biopsy

26:00 – Why transperineal biopsy may avoid antibiotics

36:00 – Prostate surgery vs. radiation: How do you choose?

42:00 – Does doing more prostatectomies make a better surgeon?

43:00 – The #1 question to ask your prostate surgeon

51:00 – What are good erectile-function outcomes after surgery?

55:00 – Nerve sparing: the surgical details that may affect erections

59:00 – The 3 questions to ask BEFORE prostate surgery

1:03:00 – Active surveillance for Gleason 6 / Grade Group 1

1:06:00 – Focal therapy: Where does it fit?

1:10:00 – Erectile dysfunction & incontinence after prostate surgery

1:11:00 – Prostate surgery after radiation or focal therapy

1:12:00 – PSMA PET scans, recurrence & salvage treatment

🔗 RESOURCES & RESEARCH

Dr. Jim Hu — Weill Cornell Medicine

https://weillcornell.org/jimhu

Follow Dr. Hu on X:

@jimhumd

PREVENT Trial — JAMA Oncology

https://jamanetwork.com/journals/jamaoncology/fullarticle/2823969

Memorial Sloan Kettering Prostate Cancer Nomogram

https://www.mskcc.org/nomograms/prostate

UK TRANSLATE Prostate Biopsy Study — The Lancet Oncology

https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(25)00100-7/fulltext

Michigan Urological Surgery Improvement Collaborative (MUSIC)

https://musicurology.com/programs/prostate/

MUSIC brings together academic and community urology practices across Michigan with the shared goal of improving prostate cancer care and patient outcomes.

Want deeper insights? Join The Dr. Geo Prostate Podcast Exclusive Membership for curated transcripts, detailed show notes, expert resources, and member perks. → https://drgeo.com/membership

___________________________________

📺 YouTube → Dr. Geo Prostate Podcast — https://www.youtube.com/@DrGeoProstatePodcast

🎧 All Episodes → Captivate.fm Archive — https://dr-geo-prostate-podcast.captivate.fm

📸 Instagram → https://bit.ly/DRGEO-INSTA-YT

📘 Facebook → https://bit.ly/POD-FB-DrGeo

💼 LinkedIn → https://bit.ly/DRGEO-LINKEDIN-YT

🛒 Supplements → XY Wellness https://bit.ly/3uJPC7Z | Mr. Happy https://bit.ly/3TE7tWE

🌐 DrGeo.com Website → https://bit.ly/43khht0

___________________________________

#DrGeoProstatePodcast #ProstateHealth #ProstateCancer #MensHealth #IntegrativeUrology #Urology

This podcast is for educational purposes only and not medical advice. The views expressed are Dr. Geo’s and not those of his employer(s) or affiliated organizations. Use of this content is at your own risk. Geovanni Espinosa, N.D., assumes no liability for direct or indirect consequences, including economic loss, injury, illness, or death.

What if one of the hardest parts of androgen deprivation therapy is not simply low testosterone—but the loss of estradiol that comes with it?

Dr. Richard Wassersug brings a rare dual perspective to that question.

He is a PhD evolutionary biologist, former professor of anatomy and neurobiology, prostate cancer quality-of-life researcher, co-developer of an androgen deprivation education program, and a patient who has used transdermal estradiol for more than two decades. His experience helped drive a deeper investigation into whether estrogen delivered through the skin could suppress testosterone while avoiding some of the burdens associated with standard LHRH-based ADT.

In this episode, you’ll learn:

🟠 Why men need estradiol for **brain, bone, sexual, and overall health.**

🟠 What the **PATCH research** suggests about transdermal estradiol, cancer control, and quality of life.

🟠 Why **hot flashes, poor sleep, fatigue, and cognitive symptoms** may reflect more than testosterone loss.

🟠 What men should know about **gynecomastia, monitoring, exercise, and shared decision-making** before considering this emerging strategy.

decision-making before considering this emerging strategy.

Chapters

00:00 ADT Side Effects Question

00:54 Podcast Disclaimers

01:33 Meet Dr Wassersug

03:59 Diagnosis And Early Treatment

04:58 Finding Estradiol Research

07:29 Lupron Side Effects And Sleep

08:48 Why Men Need Estradiol

11:00 Switching To Estradiol

15:13 NEJM Patch Trial Breakdown

20:53 Gynecomastia And Management

24:07 Real World Patient Stories

25:20 Sponsor Message Break

27:51 Access Barriers And Limits

29:03 ADT Protocols and Sleep

31:32 Estradiol Targets and Ratios

37:23 Patch vs Gel Dosing

39:10 Combining ADT With Estradiol

42:52 Who Benefits Most

44:18 PATCH Study Scope and Add-Ons

47:33 Getting Estradiol Prescribed

50:23 Suffering Mindset and Sexual Health

54:48 Active Surveillance Trial Ideas

___________________________________

Want deeper insights? Join The Dr. Geo Prostate Podcast Exclusive Membership for curated transcripts, detailed show notes, expert resources, and member perks. → https://drgeo.com/membership

___________________________________

📺 YouTube → Dr. Geo Prostate Podcast — https://www.youtube.com/@DrGeoProstatePodcast

🎧 All Episodes → Captivate.fm Archive — https://dr-geo-prostate-podcast.captivate.fm

📸 Instagram → https://bit.ly/DRGEO-INSTA-YT

📘 Facebook → https://bit.ly/POD-FB-DrGeo

💼 LinkedIn → https://bit.ly/DRGEO-LINKEDIN-YT

🛒 Supplements → XY Wellness https://bit.ly/3uJPC7Z | Mr. Happy https://bit.ly/3TE7tWE

🌐 DrGeo.com Website → https://bit.ly/43khht0

___________________________________

#DrGeoProstatePodcast #ProstateHealth #ProstateCancer #MensHealth #IntegrativeUrology #Urology

This podcast is for educational purposes only and not medical advice. The views expressed are Dr. Geo’s and not those of his employer(s) or affiliated organizations. Use of this content is at your own risk. Geovanni Espinosa, N.D., assumes no liability for direct or indirect consequences, including economic loss, injury, illness, or death.

Most men who undergo a prostate biopsy may not have cancer found at all—and the bigger mistake may be rushing from a single elevated PSA straight to the needle.

Dr. James Wysock, an NYU urologist with deep expertise in prostate cancer diagnostics and image-guided biopsy, explains why the modern biopsy decision is no longer about PSA alone. Repeat testing, prostate MRI, PSA density, blood and urine biomarkers, and expert image targeting can dramatically change who should be biopsied and how that biopsy should be performed.

Just as surprising: transperineal biopsy is not automatically “better” in every case. It clearly lowers infection and antibiotic exposure, but biopsy accuracy still depends heavily on imaging, fusion quality, sampling technique, and operator experience.

In this episode, you’ll learn...

• Why one elevated PSA should often be repeated before escalating testing.
• Why MRI may be the most important next test when biopsy risk remains concerning.
• How transperineal and transrectal biopsies really compare.
• How new fusion, needle and tissue-preservation technologies could make future biopsies shorter, more precise and less invasive.

___________________________________

Want deeper insights? Join The Dr. Geo Prostate Podcast Exclusive Membership for curated transcripts, detailed show notes, expert resources, and member perks. → https://drgeo.com/membership

___________________________________

📺 YouTube → Dr. Geo Prostate Podcast — https://www.youtube.com/@DrGeoProstatePodcast

🎧 All Episodes → Captivate.fm Archive — https://dr-geo-prostate-podcast.captivate.fm

📸 Instagram → https://bit.ly/DRGEO-INSTA-YT

📘 Facebook → https://bit.ly/POD-FB-DrGeo

💼 LinkedIn → https://bit.ly/DRGEO-LINKEDIN-YT

🛒 Supplements → XY Wellness https://bit.ly/3uJPC7Z | Mr. Happy https://bit.ly/3TE7tWE

🌐 DrGeo.com Website → https://bit.ly/43khht0

___________________________________

#DrGeoProstatePodcast #ProstateHealth #ProstateCancer #MensHealth #IntegrativeUrology #Urology

This podcast is for educational purposes only and not medical advice. The views expressed are Dr. Geo’s and not those of his employer(s) or affiliated organizations. Use of this content is at your own risk. Geovanni Espinosa, N.D., assumes no liability for direct or indirect consequences, including economic loss, injury, illness, or death.

What if the biggest mistake men make after a prostate cancer diagnosis is not eating the "wrong" food - but becoming so afraid of food that eating itself becomes stressful?

In this solo episode, Dr. Geo draws on more than two decades in holistic and integrative urology to cut through the noise around prostate cancer nutrition. Rather than promoting another rigid diet, he explains how food choices interact with physical activity, stress, metabolic signaling, and long-term sustainability. The goal is not perfection. It is to create a healthier internal environment while still enjoying life, family, and food.

In this episode, you'll learn...

• Why no single food causes or cures prostate cancer.
• How exercise and stress may change the way your body responds to food.
• Why Dr. Geo favors a plant-forward Mediterranean pattern while allowing strategic flexibility.
• How to think about protein, fish, red meat, processed foods, saturated fat, and fasting after diagnosis.

If prostate cancer nutrition has left you overwhelmed, this episode offers a simpler framework for deciding what to eat - and what actually matters most.

Chapterts

00:00 Food Myths Intro

00:55 Podcast Disclaimer

01:34 Why Nutrition Confuses

03:34 Principle One No Guilt

04:46 Stress Exercise Absorption

08:57 No Magic Foods

12:55 How Cancer Signals Work

16:40 Processed Foods And Portions

21:02 Best Diet Patterns

25:11 Protein And Muscle

28:38 Meat Poultry Fish

31:23 Carbs And Fats

35:48 Fasting And Overeating

37:17 Thrive After Diagnosis

👉 subscribe to RX3 Thursdays- https://bit.ly/3UyPJ2M

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AG1 by Athletic Greens — 75 high-quality vitamins, minerals, probiotics, and adaptogens in one daily scoop. Supports gut health, immunity, energy, and focus. Try it here → https://bit.ly/3mA2tVV

___________________________________

Want deeper insights? Join The Dr. Geo Prostate Podcast Exclusive Membership for curated transcripts, detailed show notes, expert resources, and member perks. → https://drgeo.com/membership

___________________________________

📺 YouTube → Dr. Geo Prostate Podcast — https://www.youtube.com/@DrGeoProstatePodcast

🎧 All Episodes → Captivate.fm Archive — https://dr-geo-prostate-podcast.captivate.fm

📸 Instagram → https://bit.ly/DRGEO-INSTA-YT

📘 Facebook → https://bit.ly/POD-FB-DrGeo

💼 LinkedIn → https://bit.ly/DRGEO-LINKEDIN-YT

🛒 Supplements → XY Wellness https://bit.ly/3uJPC7Z | Mr. Happy https://bit.ly/3TE7tWE

🌐 DrGeo.com Website → https://bit.ly/43khht0

___________________________________

#DrGeoProstatePodcast #ProstateHealth #ProstateCancer #MensHealth #IntegrativeUrology #Urology

This podcast is for educational purposes only and not medical advice. The views expressed are Dr. Geo’s and not those of his employer(s) or affiliated organizations. Use of this content is at your own risk. Geovanni Espinosa, N.D., assumes no liability for direct or indirect consequences, including economic loss, injury, illness, or death.

Dr. Geo welcomes Dr. Peter Bajic, Medical Director for Urology at Cleveland Clinic Main Campus and Director of Men's Health at the Glickman Urological Institute, for an evidence-based conversation about erectile dysfunction, testosterone, Peyronie's disease, and the biggest myths in men's sexual medicine.

They explore why erections reflect cardiovascular health, why "venous leak" is often misunderstood, how GLP-1 medications may temporarily influence testosterone during weight loss, and when testosterone replacement therapy is actually appropriate.

The episode also covers Peyronie's disease, treatment options including daily tadalafil and traction therapy, and practical lifestyle changes that can improve both sexual function and long-term health.

If you've ever wondered whether ED is psychological, physical, hormonal—or all three—this episode delivers clear answers backed by today's science.

• Why erectile dysfunction often predicts cardiovascular disease
• The truth about "venous leak"
• How erections actually work
• Psychological vs. physical causes of ED
• GLP-1 medications and testosterone explained
• When testosterone replacement is appropriate
• The biggest myths about Peyronie's disease
• Daily Cialis beyond erectile dysfunction
• Lifestyle strategies that improve sexual health
• The latest treatments available for men

00:00 Introduction: ED may be your first warning sign

02:45 Why erections are a window into overall health

06:20 Psychological vs. physical erectile dysfunction

13:15 GLP-1 medications, weight loss & testosterone

18:30 Combining GLP-1 therapy with testosterone replacement

28:45 The truth about "venous leak" explained

40:05 Why most men do NOT have true venous leak

43:10 The best approach to treating erectile dysfunction

49:20 Understanding Peyronie's disease

54:20 Can Peyronie's disease be prevented?

58:00 Why daily Cialis may be one of men's most useful medications

1:01:00 Xiaflex, surgery & future Peyronie's treatments

___________________________________

Want deeper insights? Join The Dr. Geo Prostate Podcast Exclusive Membership for curated transcripts, detailed show notes, expert resources, and member perks. → https://drgeo.com/membership

___________________________________

📺 YouTube → Dr. Geo Prostate Podcast — https://www.youtube.com/@DrGeoProstatePodcast

🎧 All Episodes → Captivate.fm Archive — https://dr-geo-prostate-podcast.captivate.fm

📸 Instagram → https://bit.ly/DRGEO-INSTA-YT

📘 Facebook → https://bit.ly/POD-FB-DrGeo

💼 LinkedIn → https://bit.ly/DRGEO-LINKEDIN-YT

🛒 Supplements → XY Wellness https://bit.ly/3uJPC7Z | Mr. Happy https://bit.ly/3TE7tWE

🌐 DrGeo.com Website → https://bit.ly/43khht0

___________________________________

#DrGeoProstatePodcast #ProstateHealth #ProstateCancer #MensHealth #IntegrativeUrology #Urology

This podcast is for educational purposes only and not medical advice. The views expressed are Dr. Geo’s and not those of his employer(s) or affiliated organizations. Use of this content is at your own risk. Geovanni Espinosa, N.D., assumes no liability for direct or indirect consequences, including economic loss, injury, illness, or death.

For decades, men with high-risk prostate cancer have routinely been told they need 18 to 36 months of androgen deprivation therapy (ADT) alongside radiation.

But what if 12 months is enough?

In this episode of the Dr. Geo Prostate Podcast, Dr. Geo Espinosa welcomes internationally recognized radiation oncologist Dr. Dan Spratt, Chair of Radiation Oncology at University Hospitals/Case Western Reserve University, to discuss groundbreaking research that could change how advanced prostate cancer is treated.

Together they explore the latest MARCAP consortium data suggesting many men may receive the same cancer control with significantly less hormone therapy—potentially reducing years of unnecessary side effects while maintaining excellent outcomes. They also discuss how physicians personalize treatment decisions, the growing role of artificial intelligence with Artera AI, and why the future of prostate cancer treatment may involve doing less, not more.

If you or someone you love is facing radiation therapy for prostate cancer, this episode provides one of the most important conversations happening in prostate cancer care today.

✔ Why 2-3 years of ADT may not be necessary for many patients

✔ The new evidence supporting approximately 12 months of hormone therapy

✔ Why longer hormone therapy can permanently affect testosterone recovery

✔ How physicians balance cancer control with quality of life

✔ The difference between NCCN guidelines and individualized patient care

✔ Which patients may still benefit from longer hormone therapy

✔ How AI (Artera AI) is helping personalize prostate cancer treatment

✔ Why prostate cancer care is shifting toward treatment de-intensification

✔ The future of precision medicine in radiation oncology

00:00 Introduction

01:30 Meet Dr Dan Spratt

02:22 Why ADT Lasts Years

05:42 How ADT Helps Radiation

08:49 Personalizing ADT Duration

12:39 Guidelines and Real World Use

18:03 Who Needs Long Term ADT

21:13 Artera AI Explained

23:19 Old Data and Modern Outcomes

27:28 De Intensification Future

31:33 Biomarkers for Urologists

33:57 Choosing Artera vs Decipher

37:28 Final Takeaways and Outro

• New MARCAP consortium analysis on ADT duration
• Radiation sensitivity and androgen deprivation
• Why many men never fully recover testosterone after prolonged ADT
• Balancing survival outcomes with quality of life
• Shared decision-making between physician and patient
• Genomic classifiers including Decipher
• AI biomarkers and Artera AI
• Personalized radiation oncology
• Modern imaging and PSMA PET
• De-intensifying prostate cancer treatment
• Precision medicine in localized prostate cancer
• The future of individualized prostate cancer care

• MARCAP Consortium research on androgen deprivation therapy duration

• NCCN Prostate Cancer Guidelines (discussed throughout the episode)

• Artera AI clinical decision support platform (discussion)

• Decipher genomic classifier

• PSMA PET imaging

• MRI-guided prostate cancer staging

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Want deeper insights? Join The Dr. Geo Prostate Podcast Exclusive Membership for curated transcripts, detailed show notes, expert resources, and member perks. → https://drgeo.com/membership

___________________________________

📺 YouTube → Dr. Geo Prostate Podcast — https://www.youtube.com/@DrGeoProstatePodcast

🎧 All Episodes → Captivate.fm Archive — https://dr-geo-prostate-podcast.captivate.fm

📸 Instagram → https://bit.ly/DRGEO-INSTA-YT

📘 Facebook → https://bit.ly/POD-FB-DrGeo

💼 LinkedIn → https://bit.ly/DRGEO-LINKEDIN-YT

🛒 Supplements → XY Wellness https://bit.ly/3uJPC7Z | Mr. Happy https://bit.ly/3TE7tWE

🌐 DrGeo.com Website → https://bit.ly/43khht0

___________________________________

#DrGeoProstatePodcast #ProstateHealth #ProstateCancer #MensHealth #IntegrativeUrology #Urology

This podcast is for educational purposes only and not medical advice. The views expressed are Dr. Geo’s and not those of his employer(s) or affiliated organizations. Use of this content is at your own risk. Geovanni Espinosa, N.D., assumes no liability for direct or indirect consequences, including economic loss, injury, illness, or death.

We’ve been told for decades that giving testosterone to a man with prostate cancer is like throwing gasoline on a fire. But what if, in the right context, it actually acts as the extinguisher?” It sounds like medical heresy, yet this is the foundation of Bipolar Androgen Therapy (BAT). Imagine a treatment that intentionally cycles your hormones from extreme highs to extreme lows to "overload" cancer cells and reset their sensitivity to medicine.

In this episode, we sit down with a true pioneer of this paradigm shift: Dr. Michael Schweizer. An Associate Professor at the Fred Hutchinson Cancer Center and a key architect behind the original BAT trials at Johns Hopkins, Dr. Schweizer is the scientist moving the bar for men with advanced, castrate-resistant disease. We’re moving past the fear-based dogma to look at the clinical data that proves supraphysiologic testosterone isn't just a quality-of-life booster—it’s a sophisticated weapon against resistant tumors.

In this episode, you’ll learn:

• The "Hormone Shock" Mechanism: How flooding the body with 1,500+ ng/dL of testosterone causes "mitotic catastrophe" in cancer cells adapted to low-androgen environments.
• The Resensitization Secret: Why cycling BAT can actually "reset" your cancer, making drugs like Enzalutamide work again after they’ve failed.
• Precision Selection: Which specific genetic mutations (like TP53) might predict who becomes an "exceptional responder" to high-dose testosterone.
• The Sequential Strategy: Why the order of your treatments—BAT first, then RPIs—could potentially extend survival by nearly 10 months.

00:00 Introduction: Can Testosterone Treat Prostate Cancer?

02:00 The surprising origin of Bipolar Androgen Therapy (BAT)

04:10 ⭐ Stop & Watch: Why Charles Huggins hinted at this decades ago

07:10 Why ordinary testosterone therapy failed—and BAT didn't

08:20 ⭐ Stop & Watch: The BAT protocol explained (400 mg every 28 days)

10:00 Why BAT is only used in castration-resistant prostate cancer

14:05 ⭐ Stop & Watch: The TRANSFORMER trial—did BAT actually work?

16:20 ⭐ Stop & Watch: How BAT may make failed treatments work again

20:30 ⭐ Stop & Watch: If testosterone isn't the enemy...why do we suppress it?

22:10 ⭐ Must Watch: The biology that completely changes how we think about testosterone

24:10 How BAT damages cancer DNA

26:30 BAT, quality of life, and survival—what the evidence really shows

30:00 ⭐ Stop & Watch: The sequencing strategy that could add months of cancer control

31:30 Which patients may respond best to BAT?

33:20 ⭐ Must Watch: Why every advanced prostate cancer patient should consider genetic testing

36:00 Can someone on ADT simply start testosterone?

40:00 Where BAT fits among today's prostate cancer treatments

43:00 ⭐ Stop & Watch: BAT + Lutetium PSMA—the next frontier

45:00 How to find BAT clinical trials

47:00 Should hormone therapy ever be stopped?

____________________________________

Want deeper insights? Join The Dr. Geo Prostate Podcast Exclusive Membership for curated transcripts, detailed show notes, expert resources, and member perks. → https://drgeo.com/membership

___________________________________

📺 YouTube → Dr. Geo Prostate Podcast — https://www.youtube.com/@DrGeoProstatePodcast

🎧 All Episodes → Captivate.fm Archive — https://dr-geo-prostate-podcast.captivate.fm

📸 Instagram → https://bit.ly/DRGEO-INSTA-YT

📘 Facebook → https://bit.ly/POD-FB-DrGeo

💼 LinkedIn → https://bit.ly/DRGEO-LINKEDIN-YT

🛒 Supplements → XY Wellness https://bit.ly/3uJPC7Z | Mr. Happy https://bit.ly/3TE7tWE

🌐 DrGeo.com Website → https://bit.ly/43khht0

___________________________________

#DrGeoProstatePodcast #ProstateHealth #ProstateCancer #MensHealth #IntegrativeUrology #Urology

This podcast is for educational purposes only and not medical advice. The views expressed are Dr. Geo’s and not those of his employer(s) or affiliated organizations. Use of this content is at your own risk. Geovanni Espinosa, N.D., assumes no liability for direct or indirect consequences, including economic loss, injury, illness, or death.