October 15, 2025

The Hidden Link Between HLA-B27 and CIRS (no one’s talking about this)

22 minutes

For more info and support, visit us over at https://thecirsgroup.com

In this episode of The CIRS Group podcast, hosts Barbara and Jacie dive into the specifics of ankylosing spondylitis, an autoimmune condition that Jacie personally struggled with. They discuss the genetic aspects tied to the HLA-B27 gene and its role in autoimmune disorders, including ankylosing spondylitis, acute anterior uveitis, reactive arthritis, and inflammatory bowel disease. Jacie shares a detailed account of her rapid symptom progression and how treatment for CIRS (chronic inflammatory response syndrome) brought her significant relief. The episode highlights the overlap between CIRS and autoimmune conditions, emphasizing the importance of addressing environmental toxins for effective treatment.

For more info and support, visit us over at https://thecirsgroup.com

TIMESTAMPS

00:00 Introduction and medical disclaimer

01:24 Understanding HLA-B27 and it's connection to autoimmune conditions

03:29 Jacie's experience with Ankylosing Spondylitis

6:50 America's Sweethearts Dallas Cowboys reference to AS

8:03 The connection of arthritis and eyeballs

8:40 Triggers and progression of Ankylosing Spondylitis

11:42 Treatment and Management for Ankylosing Spondylitis

12:35 Interesting connection to Klebsiella

13:25 How CIRS treatment cured Jacie's AS

16:11 Overlap between HLA-B27 and CIRS

19:00 Conclusion and Encouragement

HELPFUL LINKS:

Order Jacie's book! The 30 Day Carnivore Bootcamp: https://a.co/d/7MgHrRs

The CIRS Group:

Support Community: https://thecirsgroup.com

Instagram: https://www.instagram.com/thecirsgroup/

Find Jacie for carnivore, lifestyle and limbic resources:

Jacie’s book on the Carnivore diet! https://a.co/d/8ZKCqz0

Instagram: https://www.instagram.com/ladycarnivory

YouTube: https://www.youtube.com/@LadyCarnivory

Blog: https://www.ladycarnivory.com/

Find Barbara for business/finance tips and coaching:

Website: https://www.actlikebarbara.com/

Instagram: https://www.instagram.com/actlikebarbara/

YouTube: https://www.youtube.com/@actlikebarbara

Jacie is a Shoemaker certified Proficiency Partner, NASM certified nutrition coach, author, and carnivore recipe developer determined to share the life changing information of carnivore and CIRS to anyone who will listen. Barbara is a business and fitness coach, CIRS and ADHD advocate, writer, speaker, and a big fan of health and freedom. Together, they co-founded The CIRS Group, an online support community to help people that are struggling with their CIRS diagnosis and treatment.

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