Are you curious about how cocaine works in the body and the secrets behind successful drug testing? Look no further! In this eye-opening video, I delve deep into cocaine's kinetics, covering everything from absorption and distribution to metabolism and excretion. We explore how various routes of administration—like snorting, smoking, and injection—affect cocaine's absorption rate and the resulting emotional highs. Learn why bioavailability is greatest through inhalation and intravenous use, and discover the factors influencing this potent drug's absorption and distribution.We also highlight crucial information on cocaine metabolism, including its breakdown into metabolites like benzoylecgonine, norcocaine, and cocaethylene. You will learn why certain combinations, such as cocaine with alcohol, can lead to detrimental effects and prolonged drug detection times. Armed with this knowledge, you'll better understand the intricacies of urine drug testing and how metabolites linger in the system for days to weeks, depending on user habits.Chapters00:00:00 Introduction to Cocaine Kinetics00:00:47 Cocaine Absorption Methods00:01:48 Distribution of Cocaine00:02:35 Cocaine Metabolism00:04:22 Metabolic Pathways and Key Harm Reduction Intervention00:05:21 Detailed Metabolites of Cocaine00:07:06 Half-Life of Cocaine and Its Metabolites00:08:17 Detection Methods for Cocaine in Biological Matrices00:09:03 Overview of Biological Matrices for Cocaine Detection00:10:47 Considerations for Cocaine Detection00:11:27 Implications for Drug Testing00:12:07 Conclusion and Next Episode Preview