Docs Who Lift

The Science of Myostatin inhibitors, GLP-1 meds and Muscle Mass


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  • Dr. Grant Tinsley joins the discussion as the body composition expert.
  • Myostatin is a key regulator of muscle growth.
  • Wendy Whippete the most jacked muscled up dog
  • The concern of GLP-1 receptor agonists and muscle mass loss.
  • Overview of Courage trial looking at semaglutide and trevogrumab and lean mass loss
  • Upcoming Believe trial coming out (bimagrumab and semaglutide)
  • Exercise remains crucial for muscle health and function.
  • MRI data from SURPASS MRI provides new insights into muscle volume changes.
  • The combination of medications may have varying effects on muscle mass.
  • Caution is advised regarding the long-term effects of new drugs.
  • Clinical benefits of medications often outweigh concerns about muscle loss.
  • Future research will explore the synergy between exercise and medication.

Other docs who lift podcasts with Dr. Grant:

Tirzepatide muscle loss

Lean mass loss and GLP-1 meds

...more
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