With Dr. Abraham Morgentaler and Dr. Marianne Brandon Listen to the podcast on all of your favorite platforms: Apple: https://podcasts.apple.com/ec/podcast/the-sex-doctors/id1761813985?l=en-GB Spotify: https://open.spotify.com/show/0apSFzquJXKoOGnmI6ndgT?si=e5a1e482c7ca46c7 Find us on: Instagram: https://www.instagram.com/thesexdoctors?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw== Facebook: https://www.facebook.com/thesexdoctors YouTube: https://www.youtube.com/@thesexdoctorspod TikTok: https://www.tiktok.com/@thesexdoctor LinkedIn (Dr. Abraham): https://www.linkedin.com/in/abraham-morgentaler-md-81628b6 LinkedIn (Dr. Marianne): https://www.linkedin.com/in/mariannebrandon-59224513 X (Dr. Abraham): https://x.com/DrMorgentaler X (Dr. Marianne): https://x.com/drbrandon In this episode, Dr. Brandon & Dr. Morgentaler discuss how testosterone therapy affects cholesterol, challenge long-held beliefs about prostate cancer treatment, and explore why some of medicine's biggest assumptions may deserve a second look. 00:00 – Podcast Kickoff: The episode opens with a listener question about how oral testosterone may affect cholesterol and heart health. 00:50 – Oral Testosterone Lipids: Dr. Morgentaler explains what testosterone therapy really does to cholesterol, ApoB, and overall cardiovascular risk. 06:29 – Conference ADT Debate: Fresh from a cancer conference, Dr. Morgentaler questions why androgen deprivation therapy remains the standard treatment. 22:41 – Why ADT Comes First: The doctors discuss why ADT is still used first despite newer therapies that may offer greater benefits. 24:54 – BAT and PSA Confusion: They break down bipolar androgen therapy (BAT) and explain why PSA levels don't always tell the full story. 32:28 – Huggins Myth and Wrap Up: Dr. Morgentaler revisits the decades-old research that shaped testosterone's reputation in prostate cancer and why it's worth questioning today. Resources: Huggins C, Hodges CV. Studies on Prostatic Cancer. I. The Effect of Castration, of Estrogen and of Androgen Injection on Serum Phosphatases in Metastatic Carcinoma of the Prostate. Cancer Research. 1941;1:293-297. Morgentaler A, Rhoden EL. Prevalence of Prostate Cancer Among Hypogonadal Men With Prostate-Specific Antigen Less Than 4.0 ng/mL and Normal Digital Rectal Examination: Results of a Biopsy Study. The Journal of Urology. 2006;175(2):495-499. Morgentaler A, Rhoden EL. Risks of Testosterone-Replacement Therapy and Recommendations for Monitoring. New England Journal of Medicine. 2004;350:482-492. Tombal B, et al. The EMBARK Trial: Enzalutamide in Patients With High-Risk Biochemically Recurrent Prostate Cancer. New England Journal of Medicine. 2023. Denmeade SR, et al. Bipolar Androgen Therapy for Men With Castration-Resistant Prostate Cancer. (Johns Hopkins series of clinical trials and publications on BAT.) #testosteronetherapy #prostatecancertreatment #medicalinnovation

With Dr. Abraham Morgentaler and Dr. Marianne Brandon Listen to the podcast on all of your favorite platforms: Apple: https://podcasts.apple.com/ec/podcast/the-sex-doctors/id1761813985?l=en-GB Spotify: https://open.spotify.com/show/0apSFzquJXKoOGnmI6ndgT?si=e5a1e482c7ca46c7 Find us on: Instagram: https://www.instagram.com/thesexdoctors?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw== Facebook: https://www.facebook.com/thesexdoctors YouTube: https://www.youtube.com/@thesexdoctorspod TikTok: https://www.tiktok.com/@thesexdoctor LinkedIn (Dr. Abraham): https://www.linkedin.com/in/abraham-morgentaler-md-81628b6 LinkedIn (Dr. Marianne): https://www.linkedin.com/in/mariannebrandon-59224513 X (Dr. Abraham): https://x.com/DrMorgentaler X (Dr. Marianne): https://x.com/drbrandon In this episode, Dr. Brandon and Dr. Morgentaler talk about the FDA's groundbreaking testosterone label changes, the evolving evidence on testosterone therapy and prostate cancer, and how quality of life should factor into treatment decisions for men with advanced disease. 00:00 Listener Question Metastatic Prostate Cancer – Dr. Morgentaler explains whether testosterone or anabolic steroids may have a place in treating men with metastatic prostate cancer while preserving quality of life. 04:09 Testosterone Quality of Life Tradeoffs – The doctors discuss real patient stories and the difficult decision between maximizing survival and maintaining a meaningful quality of life. 12:46 FDA Label Update Testosterone – Dr. Morgentaler breaks down the FDA's landmark decision to update testosterone labeling based on modern scientific evidence. 18:51 Testosterone Myth Falls – Dr. Morgentaler reflects on his decades-long effort to challenge the belief that testosterone causes or fuels prostate cancer. 24:09 FDA Label Changes Explained – A detailed look at what the FDA removed, what remains on the label, and what the changes mean for doctors and patients. 28:42 What Still Needs Fixing – The conversation covers the remaining barriers to testosterone therapy, including outdated regulations and future research priorities. Resources: TRAVERSE Trial Lincoff AM, et al. Cardiovascular Safety of Testosterone-Replacement Therapy. Testosterone Does Not Drive Prostate Cancer: Presenting the New Framework of Androgen Adequacy vs Inadequacy Abraham Morgentaler, Abdulmaged M. Traish Testosterone Therapy in Men With Metastatic Prostate Cancer Abraham Morgentaler, Jonathan Krakowsky, et al. (the episode references this case series presented and later published by Morgentaler and colleagues) Testosterone Therapy in Men With Biochemical Recurrence of Prostate Cancer Abraham Morgentaler, et al. (same published case series included men with biochemical recurrence) Bipolar Androgen Therapy (BAT) Samuel R. Denmeade, Emmanuel S. Antonarakis, et al. (Johns Hopkins group that developed BAT) Modified Bipolar Androgen Therapy (Modified BAT) Abraham Morgentaler (protocol described by Dr. Morgentaler; not a widely recognized standalone published trial title) #prostatecancertreatment #testosteronetherapy #fdadecisions

With Dr. Abraham Morgentaler and Dr. Marianne Brandon Listen to the podcast on all of your favorite platforms: Apple: https://podcasts.apple.com/ec/podcast/the-sex-doctors/id1761813985?l=en-GB Spotify: https://open.spotify.com/show/0apSFzquJXKoOGnmI6ndgT?si=e5a1e482c7ca46c7 Find us on: Instagram: https://www.instagram.com/thesexdoctors?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw== Facebook: https://www.facebook.com/thesexdoctors YouTube: https://www.youtube.com/@thesexdoctorspod TikTok: https://www.tiktok.com/@thesexdoctor LinkedIn (Dr. Abraham): https://www.linkedin.com/in/abraham-morgentaler-md-81628b6 LinkedIn (Dr. Marianne): https://www.linkedin.com/in/mariannebrandon-59224513 X (Dr. Abraham): https://x.com/DrMorgentaler X (Dr. Marianne): https://x.com/drbrandon In this episode, Dr. Brandon & Dr. Morgentaler talk about how major weight loss can affect testosterone levels, why free testosterone may matter more than total testosterone in some men, and the latest research on simple ways to help men last longer in bed. 00:00 Welcome and Guest Ace The doctors welcome their special cat guest, Ace, before diving into listener questions and the latest sexual health research. 00:58 Listener Question: Low Free T A listener asks why he still has low libido and mood symptoms despite a normal total testosterone level after major weight loss. 02:05 Weight Loss & SHBG Explained Dr. Morgentaler explains how significant weight loss can raise testosterone while also increasing SHBG, which may leave free testosterone too low. 05:26 Treatment Options: TRT vs Enclomiphene The doctors compare testosterone replacement therapy and enclomiphene, discussing the pros, cons, and limitations of each approach. 09:36 Study: Benzocaine Condoms A new study shows how over-the-counter benzocaine condoms may help men last longer and improve control during sex. 16:41 Other PE Tools and Wrap Up The conversation covers additional options for premature ejaculation, including sprays, medications, breathing techniques, and training methods. #testosteronemanagement #prematureejaculationsolutions #sexualhealthresearch

With Dr. Abraham Morgentaler and Dr. Marianne Brandon Listen to the podcast on all of your favorite platforms: Apple: https://podcasts.apple.com/ec/podcast/the-sex-doctors/id1761813985?l=en-GB Spotify: https://open.spotify.com/show/0apSFzquJXKoOGnmI6ndgT?si=e5a1e482c7ca46c7 Find us on: Instagram: https://www.instagram.com/thesexdoctors?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw== Facebook: https://www.facebook.com/thesexdoctors YouTube: https://www.youtube.com/@thesexdoctorspod TikTok: https://www.tiktok.com/@thesexdoctor LinkedIn (Dr. Abraham): https://www.linkedin.com/in/abraham-morgentaler-md-81628b6 LinkedIn (Dr. Marianne): https://www.linkedin.com/in/mariannebrandon-59224513 X (Dr. Abraham): https://x.com/DrMorgentaler X (Dr. Marianne): https://x.com/drbrandon In this episode, Dr. Brandon & Dr. Morgentaler talk about the lack of evidence behind progesterone use in men, the importance of personalized testosterone treatment, and why AI-powered chatbots may dramatically change the future of therapy and mental health care. 00:00 Listener Question: Progesterone Dr. Morgentaler explains why progesterone is sometimes used in men but says there is very little evidence showing meaningful benefits for sleep, mood, or overall health. 04:21 Testosterone Guidelines Reality The doctors discuss how testosterone treatment should be personalized, not based solely on guidelines or lab numbers. 08:37 AI Threat to Therapy A deep dive into how AI could disrupt psychotherapy and why many mental health professionals may be underestimating the impact. 16:15 Chatbots Feel Like Connection The hosts explore how AI chatbots can create a surprising sense of emotional connection and companionship. 17:11 Why People Prefer AI Therapy They discuss why some people find AI therapy more appealing, including convenience, accessibility, affordability, and constant availability. 22:53 Therapists Adapt and Future Outlook Dr. Brandon shares how therapists may need to evolve, specialize, and lean into human connection to stay relevant in an AI-driven future. #hormonetherapy #aiinpsychotherapy #futureoftherapy

With Dr. Abraham Morgentaler and Dr. Marianne Brandon Listen to the podcast on all of your favorite platforms: Apple: https://podcasts.apple.com/ec/podcast/the-sex-doctors/id1761813985?l=en-GB Spotify: https://open.spotify.com/show/0apSFzquJXKoOGnmI6ndgT?si=e5a1e482c7ca46c7 Find us on: Instagram: https://www.instagram.com/thesexdoctors?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw== Facebook: https://www.facebook.com/thesexdoctors YouTube: https://www.youtube.com/@thesexdoctorspod TikTok: https://www.tiktok.com/@thesexdoctor LinkedIn (Dr. Abraham): https://www.linkedin.com/in/abraham-morgentaler-md-81628b6 LinkedIn (Dr. Marianne): https://www.linkedin.com/in/mariannebrandon-59224513 X (Dr. Abraham): https://x.com/DrMorgentaler X (Dr. Marianne): https://x.com/drbrandon In this episode, Dr. Brandon and Dr. Morgentaler talk about navigating sexual differences in relationships, the latest evidence supporting testosterone therapy after prostate cancer treatment, and practical ways couples can rebuild intimacy and sexual confidence during recovery. 00:00 – Welcome and Setup The hosts introduce the episode and preview discussions on relationship communication, sexual exploration, and prostate cancer recovery. 00:43 – Partner Won't Experiment Dr. Brandon shares advice on navigating sexual differences, emphasizing communication, curiosity, and mutual understanding over pressure. 07:19 – Testosterone After Prostatectomy A new randomized controlled trial examines testosterone therapy in men after prostate cancer surgery and its impact on safety and quality of life. 18:09 – Debunking Old Testosterone Fears Dr. Morgentaler explains why decades-old beliefs linking testosterone to prostate cancer continue to persist despite growing evidence to the contrary. 21:23 – Rebuilding Intimacy After Prostate Cancer The doctors discuss the emotional and physical challenges couples face after treatment and how to reconnect through communication and touch. 29:05 – ED Treatments and Closing Takeaways The episode reviews erectile dysfunction treatment options after prostate cancer and offers practical encouragement for men and their partners. #sexualhealth #testosteronetherapy #prostatecancerrecovery

With Dr. Abraham Morgentaler and Dr. Marianne Brandon Listen to the podcast on all of your favorite platforms: Apple: https://podcasts.apple.com/ec/podcast/the-sex-doctors/id1761813985?l=en-GB Spotify: https://open.spotify.com/show/0apSFzquJXKoOGnmI6ndgT?si=e5a1e482c7ca46c7 Find us on: Instagram: https://www.instagram.com/thesexdoctors?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw== Facebook: https://www.facebook.com/thesexdoctors YouTube: https://www.youtube.com/@thesexdoctorspod TikTok: https://www.tiktok.com/@thesexdoctor LinkedIn (Dr. Abraham): https://www.linkedin.com/in/abraham-morgentaler-md-81628b6 LinkedIn (Dr. Marianne): https://www.linkedin.com/in/mariannebrandon-59224513 X (Dr. Abraham): https://x.com/DrMorgentaler X (Dr. Marianne): https://x.com/drbrandon In this episode, Dr. Brandon and Dr. Morgentaler talk about the safety of hormone replacement therapy after age 65, breaking down common misconceptions from the WHI study and explaining why many fears about starting hormones later in life may be overstated. 00:00 – Listener Question on Late HRT A listener asks whether starting hormone replacement therapy more than 10 years after menopause is safe, sparking a discussion on hormones after age 65. 01:56 – WHI Study Misread and Risk Math The doctors break down how the WHI study was widely misinterpreted and explain the actual breast cancer risk numbers behind the headlines. 15:43 – New Study After 65 A recently published study raises concerns about starting hormone therapy after age 65, prompting a closer look at its findings. 17:22 – Study Design Red Flags Dr. Morgentaler highlights major flaws in the study's methodology and explains why he believes the results are not reliable. 23:36 – Peer Review Pitfalls The conversation explores how questionable research can still make it through peer review and influence medical opinions. 28:17 – HRT After 65 Guidance The doctors discuss why many women may still benefit from hormone therapy later in life and how treatment decisions should be individualized. #hormonereplacementtherapy #womenshealth #menopauseresearch

With Dr. Abraham Morgentaler and Dr. Marianne Brandon Listen to the podcast on all of your favorite platforms: Apple: https://podcasts.apple.com/ec/podcast/the-sex-doctors/id1761813985?l=en-GB Spotify: https://open.spotify.com/show/0apSFzquJXKoOGnmI6ndgT?si=e5a1e482c7ca46c7 Find us on: Instagram: https://www.instagram.com/thesexdoctors?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw== Facebook: https://www.facebook.com/thesexdoctors YouTube: https://www.youtube.com/@thesexdoctorspod TikTok: https://www.tiktok.com/@thesexdoctor LinkedIn (Dr. Abraham): https://www.linkedin.com/in/abraham-morgentaler-md-81628b6 LinkedIn (Dr. Marianne): https://www.linkedin.com/in/mariannebrandon-59224513 X (Dr. Abraham): https://x.com/DrMorgentaler X (Dr. Marianne): https://x.com/drbrandon In this episode, Dr. Brandon and Dr. Morgentaler talk about a listener's question on reduced sexual sensation during intercourse and explore modern relationship dynamics, attraction, confidence, intimacy, and the common misconceptions men and women have about each other. 00:00 Listener Question: Penis Numbness – Dr. Brandon and Dr. Morgentaler answer a listener's question about loss of sexual sensation and explore potential physical and hormonal causes. 02:00 Testosterone, Sensation & Hormones – The doctors discuss how testosterone and aging can affect genital sensitivity, arousal, and overall sexual function. 09:46 Myth: Men Prefer Passive Women – The conversation challenges the stereotype that men want passive partners, arguing that confidence and engagement are far more attractive. 16:10 The Passive Partner Myth – Drawing from decades of clinical experience, the hosts explain why most people prefer assertive, enthusiastic partners both in and out of the bedroom. 20:42 Assertiveness and Vulnerability – The discussion explores how taking initiative in intimacy requires vulnerability, confidence, and a willingness to risk rejection. 26:08 Fifty Shades Takeaways – Using Fifty Shades of Grey as an example, the hosts examine attraction, power dynamics, and what the book's popularity may reveal about sexual psychology. #sexualhealth #modernmasculinity #healthyrelationships

With Dr. Abraham Morgentaler and Dr. Marianne Brandon Listen to the podcast on all of your favorite platforms: Apple: https://podcasts.apple.com/ec/podcast/the-sex-doctors/id1761813985?l=en-GB Spotify: https://open.spotify.com/show/0apSFzquJXKoOGnmI6ndgT?si=e5a1e482c7ca46c7 Find us on: Instagram: https://www.instagram.com/thesexdoctors?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw== Facebook: https://www.facebook.com/thesexdoctors YouTube: https://www.youtube.com/@thesexdoctorspod TikTok: https://www.tiktok.com/@thesexdoctor LinkedIn (Dr. Abraham): https://www.linkedin.com/in/abraham-morgentaler-md-81628b6 LinkedIn (Dr. Marianne): https://www.linkedin.com/in/mariannebrandon-59224513 X (Dr. Abraham): https://x.com/DrMorgentaler X (Dr. Marianne): https://x.com/drbrandon In this episode, Dr. Brandon and Dr. Morgentaler welcome Dr. Abdulmaged Traish, world-renowned hormone researcher and professor emeritus at Boston University, to talk about his incredible journey from growing up in a poor village with no electricity or running water to becoming one of the world's leading experts in testosterone and steroid hormone research. 00:00 Meet Dr. Abdulmaged Traish – Dr. Abdulmaged Traish shares his remarkable journey from a small farming village in Libya to becoming one of the world's leading hormone researchers. 02:34 From Libya to Boston University – Hear how determination, curiosity, and resilience helped Dr. Traish overcome extreme hardships and build an extraordinary academic career. 28:26 Steroid Science to Sexual Medicine – Dr. Traish explains how his research evolved from steroid hormones and biochemistry into groundbreaking work in sexual medicine. 41:14 JAMA Testosterone Scare – The discussion breaks down the controversial JAMA study that sparked widespread concerns about testosterone therapy and cardiovascular risk. 46:04 Teaching Critical Reading – Dr. Traish highlights the importance of questioning research, analyzing data carefully, and avoiding misleading scientific conclusions. 01:01:46 Testosterone Science and Women – The conversation explores the often-overlooked role of testosterone in women's health, well-being, and sexual function. Resources: Vigen R, O'Donnell CI, Barón AE, et al. Association of Testosterone Therapy With Mortality, Myocardial Infarction, and Stroke in Men With Low Testosterone Levels. JAMA. 2013;310(17):1829-1836. #scientistjourney #hormoneresearch #educationinspiration

With Dr. Abraham Morgentaler and Dr. Marianne Brandon Listen to the podcast on all of your favorite platforms: Apple: https://podcasts.apple.com/ec/podcast/the-sex-doctors/id1761813985?l=en-GB Spotify: https://open.spotify.com/show/0apSFzquJXKoOGnmI6ndgT?si=e5a1e482c7ca46c7 Find us on: Instagram: https://www.instagram.com/thesexdoctors?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw== Facebook: https://www.facebook.com/thesexdoctors YouTube: https://www.youtube.com/@thesexdoctorspod TikTok: https://www.tiktok.com/@thesexdoctor LinkedIn (Dr. Abraham): https://www.linkedin.com/in/abraham-morgentaler-md-81628b6 LinkedIn (Dr. Marianne): https://www.linkedin.com/in/mariannebrandon-59224513 X (Dr. Abraham): https://x.com/DrMorgentaler X (Dr. Marianne): https://x.com/drbrandon In this episode, Dr. Brandon & Dr. Morgentaler talk about age-related changes in orgasm intensity, treatments for delayed orgasm, and the pros and cons of oral, topical, injectable, and pellet testosterone therapy. 00:00 Aging and Delayed Orgasm The Doctors discuss why orgasms may become more difficult with age and what delayed orgasm means for men and women. 01:23 Treatments and Practical Tips A look at testosterone, oxytocin, medications, and practical strategies that may help improve orgasm frequency and satisfaction. 07:37 Testosterone Options Debate Dr. Morgentaler breaks down the latest debate on oral, topical, injectable, and pellet testosterone therapies. 14:38 Topical Transfer Risks How testosterone creams work, what patients should know about absorption, and the realities of transfer risks. 18:11 Injections and Pellets The pros, cons, and convenience of testosterone injections and long-lasting pellet therapy. 25:57 Matching Treatment and Wrap Why the best testosterone treatment depends on the individual—and how finding the right fit improves long-term success. #sexualhealth #agingandsexuality #testosteronetherapy

With Dr. Abraham Morgentaler and Dr. Marianne Brandon Listen to the podcast on all of your favorite platforms: Apple: https://podcasts.apple.com/ec/podcast/the-sex-doctors/id1761813985?l=en-GB Spotify: https://open.spotify.com/show/0apSFzquJXKoOGnmI6ndgT?si=e5a1e482c7ca46c7 Find us on: Instagram: https://www.instagram.com/thesexdoctors?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw== Facebook: https://www.facebook.com/thesexdoctors YouTube: https://www.youtube.com/@thesexdoctorspod TikTok: https://www.tiktok.com/@thesexdoctor LinkedIn (Dr. Abraham): https://www.linkedin.com/in/abraham-morgentaler-md-81628b6 LinkedIn (Dr. Marianne): https://www.linkedin.com/in/mariannebrandon-59224513 X (Dr. Abraham): https://x.com/DrMorgentaler X (Dr. Marianne): https://x.com/drbrandon In this episode, Dr. Brandon & Dr. Morgentaler talk about why orgasms may become less intense with age, treatment options that may help, and what the science actually says about pornography's impact on sexual function and relationships. 00:00 Welcome to The Sex Doctors The Sex Doctors tackle listener questions about aging, orgasm changes, and the science behind pornography and sexual health. 00:26 Aging and Orgasm Changes Why orgasms can feel less intense with age—and what men and women can do to improve sexual satisfaction. 01:38 Foreplay for Your Foreplay Dr. Brandon explains how warming up before intimacy can increase arousal, pleasure, and orgasm intensity. 03:15 Hormones and Med Options A look at estrogen, testosterone, Addyi, and other treatment options that may help improve sexual function. 07:28 Does Porn Harm Sex The doctors separate myths from science and explore whether pornography actually causes sexual dysfunction or relationship problems. 21:48 Porn Myths and Wrap Up A final discussion on porn addiction, sexual satisfaction, and the relationship factors that matter most. #womensexualhealth #agingandorgasm #pornandsexualfunction