Host: Vincent Racaniello

Guests: Michael Diamond, Michaela Gack, Laura Kramer, and Charles Rice

Four virologists discuss our current understanding of Zika virus biology, pathogenesis, transmission, and prevention, in this special live episode recorded at the American Society for Microbiology in Washington, DC.

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Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Guests: David Pride and Forest Rohwer

If you have always wanted to know what coral reefs and the human oral cavity have in common, listen as guests David Pride and Forest Rohwer talk about their work on the microbiomes and viromes of these two environments, and you'll also understand why mucus is cool.

• Lytic to temperate switching of viral communities (Nature)
• Viromes in ancestral holobiont Hydra (PLoS One)
• Phage in human oral cavity (J Oral Micro)
• Human oral viruses are personal, consistent, gender specific (ISME)
• Video of this episode at YouTube

This episode is sponsored by CuriosityStream. Get two months free when you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Alan - Vax Pack HeroRich - Helicopter autorotation Vincent - Live in Our Phage World by Forest Rohwer, Merry Youle, Heather Maughan, Nao Hisakawa

Matt - Experiment.com

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Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler

Guests: Ethan Jackson and Jonathan Carlson

Project Premonition, a Microsoft Research project that uses drones to capture mosquitoes and analyze them for pathogens, preprint servers, and three mouse models for Zika virus induced birth defects are the topics of this episode hosted by the TWiumvirate and theirs guests Ethan and Jonathan.

• Project Premonition
• Premonition feasibility study in Grenada
• Zika virus causes microcephaly in mice (Cell Stem Cell)
• Brazilian Zika virus causes defects in experimental models (Nature)
• Zika virus causes placental damage and fetal demise in mice (Cell)
• Letters read on TWiV 390

This episode is sponsored by CuriosityStream. Get two months free when you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Also brought to you by ASV 2016

Dickson - Germany nearly reached 100% renewable power Alan - Vertical City documentary and Lumino City gameRich - Errol Morris: 'Demon in the Freezer' Kathy - Entropic Time YouTube by A Capella Science (watch "the making of")Vincent - Agar Art contest finalists

Jennie - SciFi reading (scroll down)

Send your virology questions and comments to [email protected]

Host: Vincent Racaniello

Guest: Stan Lemon

Vincent speaks with Stan Lemon about his career in virology, from early work on Epstein Barr virus, through making essential discoveries about hepatitis A virus, hepatitis C virus, and rhinoviruses.

• Live in Edmonton, Eh? (TWiV 235)
• Replication of EBV in epithelial cells (Nature)
• Returning to Carolina after 14 years
• Evolutionary origins of hepatitis A virus (TWiV 265)
• cre in rhinovirus genome (RNA)
• Naked viruses that aren't always naked (Ann Rev Virol)
• miR-122 and hepatitis C virus RNA (Cell Host Micr)

This episode is sponsored by CuriosityStream. Get two months free when you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Send your virology questions and comments to [email protected]

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler

Preprint servers, the structure of an antibody bound to Zika virus, blocking Zika virus replication in mosquitoes with Wolbachia, and killing carp in Australia with a herpesvirus are topics of this episode hosted by Vincent, Dickson, Alan, and Kathy.

Links for this episode

• biorXiv preprint server
• Please review Vaccines and Your Child
• Structure of antibody bound to Zika virus E protein (Cell Host Microbe)
• Wolbachia blocks Zika virus in mosquitoes (Cell Host Microbe)
• Zimmer on Wolbachia and Zika virus (NY Times)
• Fauci on Zika virus vaccine (Science)
• Carpageddon (The Conversation)
• Letters read on TWiV 388

This episode is sponsored by CuriosityStream. Get two months free when you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Also brought to you by ASV 2016

Dickson - EarthEnv Alan - Research funding by lottery Kathy - Eugenia Cheng Math and BakingVincent - Zika Diaries

Stephen - Virus trading cards William - Virus trading cards Norma+Maurice - Virus trading cards Tom - Virus trading cards

Send your virology questions and comments to [email protected]

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler

Guest: Nina Martin

Nina Martin joins the TWiV team to talk about the movie Vaxxed, her bout with dengue fever, and the latest research on Zika virus.

• Public Health United
• Fifty Shades of Science (TEDx)
• Parents convicted in death of toddler (Science Based Medicine)
• CDC: Zika virus causes microcephaly (NEJM)
• Dengue virus antibodies enhance Zika virus infection (biorXiv)
• Zika virus in Brazilian nonhuman primates (biorXiv)
• Zika virus IgM in CSF of microcephalic babies (Lancet)
• Brain organoids for modeling Zika virus infection (Cell)
• Letters read on TWiV 387

This episode is sponsored by CuriosityStream. Get two months free when you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Also brought to you by ASV 2016

Nina - Vaccines and Your Child by Paul Offit and Charlotte MoserDickson - The animals of Chernobyl Alan - Five rules of lab safety Kathy - 20 best science images of the year?Vincent - Massive undersea crab swarm

JP - Global map of wind Todd - Doc Martin

Send your virology questions and comments to [email protected]

Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler

Guests: Ted Diehl and Welkin Johnson

Ted and Welkin inform the TWiV team how the evolution of ancient retroviruses can be inferred by studying their sequences in the genomes of modern mammals, and join in a discussion of virus dispersal during different methods for drying hands.

• More fun than a monkey full of viruses (TWiV 122)
• Tracking ancient retrovirus evolution in mammals (eLife)
• Virus dispersal during hand drying (J Appl Micro)
• More than you wanted to know about hand drying (one, two, three, four, five, six)

This episode is sponsored by ASM Agar Art Contest, ASM Grant Writing Course, and ASV 2016

Welkin - Lab Girl by Hope Jahren (essay)Ted - Accidental brilliance in scienceRich - Perpetual motion?Kathy - R0 graphic and explanationVincent - NWS ditches all caps forecasts

Basel - Gimli Glider and Mars Climate OrbiterKen - Vaccination comic book

Send your virology questions and comments to [email protected]

Hosts: Vincent Racaniello and Dickson Despommier

Guest: Stuart Firestein

Stuart joins Vincent and Dickson to talk about his sequel to Ignorance, a book called Failure, which seeks to make science more appealing by revealing its faults.

• Stuart Firestein's site
• Ignorance with Stuart Firestein (TWiV Special)
• The pursuit of ignorance (TED)
• Ignorance by Stuart Firestein
• Failure by Stuart Firestein

This episode is sponsored by ASM Agar Art Contest and ASV 2016

Send your virology questions and comments to [email protected]

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove and Rich Condit

Guests: Nischay Mishra and Ian Lipkin

Nischay and Ian join the TWiVions to discuss mass die-offs of tilapia by a novel orthomyxo-like virus, Ian's editorial on the movie Vaxxed, and new vaccines to prevent dengue virus infections, including a human challenge model.

• Novel orthomyxo-like virus in Tilapia die-offs (mBio)
• Fish flu (TWiV 41)
• Anti-vaccination lunacy won't stop (WSJ)
• Single-dose dengue vaccine effective (J Inf Dis)
• Dengue vaccine needs (J Inf Dis)
• Composition of TV003 (J Inf Dis)
• Dengue vaccine mutagenesis (Curr Top Micr Imm)
• Dengue human challenge model (Sci Transl Med)
• Yellow fever alarm (STAT)
• Experiment: Zika virus
• UC Berkeley Microbiology Student Symposium
• Image credit
• Letters read on TWiV 384

This episode is sponsored by ASM Agar Art Contest, ASM Grant Writing Course, and ASV 2016

Rich - Dune by Frank HerbertAlan - Adult vaccination video contestDickson - Ski town greenhouseVincent - Preprint servers: Force awakens or revenge of undead?

Ken - Golden Mole Awards for Accidental Brilliance (list, video)Jim - Linear algebra course

Send your virology questions and comments to [email protected]

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove and Kathy Spindler

Guest: Esper Kallas

Esper and the Merry TWiXters analyze the latest data on Zika virus and microcephaly in Brazil, and discuss publications on a mouse model for disease, infection of a fetus, mosquito vector competence, and the cryo-EM structure of the virus particle.

• Zika virus in the Americas (Science)
• Co-circulation of dengue, Zika, chik in Brazil (Medicine)
• Murine model for Zika virus infection (Am J Trop Med Hyg)
• Zika virus susceptibility of A. aegypti and A. albopictus (PLoS NTD)
• Infectious Zika virus from saliva (EuroSurveill)
• Zika virus spread through saliva? (Braz Oral Res)
• Five Zika virus reviews (one, two, three, four, five)
• Zika virus and microcephaly, Brazil (MMWR)
• Zika virus in urine (EuroSurveill)
• Zika virus infection of fetus (NEJM)
• Real-time sharing of Zika virus data (JAMA)
• Image credit: Richard Kuhn
• Letters read on TWiV 383

This episode is sponsored by ASM Agar Art Contest and ASV 2016

Esper - The Chaos by Gérard Nolst Trenité and HIV pathogenesis courseAlan - Science KombatDickson - Four steps to wiping out a mosquitoVincent - Public lacks information on Zika virusKathy - Zika virus cryo-EM structure video

Justin - Culture-independent discovery of Archaeal virusMelinda - Zika virus open research portal and Your body battles series

Send your virology questions and comments to [email protected]