In this Unreasonable Health episode, Cade and Regan Archibald dive into the science behind optimizing brain health and performance through strategies like boosting Brain-Derived Neurotrophic Factor (BDNF). Regan emphasizes the importance of activities such as high-intensity exercise, fasting, sun exposure, and consuming specific foods like turmeric, fatty fish, and coffee to enhance BDNF. They also discuss the impact of peptides, particularly IGF-1, on brain function and neuroplasticity. The episode encourages listeners to adopt challenging but rewarding health habits, as tasks that are initially difficult—like exercise and dietary adjustments—become easier over time. These habits significantly contribute to long-term health and cognitive function. Regan concludes with a challenge for listeners to incorporate daily activities that push their limits and promote neuroplasticity.