In this conversation, Joel Evan interviews Mac Davis, the founder and CEO of MiniCircle, a pioneering company in gene therapy. They discuss Mac's unique background as a former monk and how it influenced his journey into biotechnology. The conversation delves into the mechanisms of gene therapy, particularly focusing on follistatin, its potential to reverse aging, and the safety of such treatments. Mac shares insights from clinical trials, real-world applications, and the process of receiving gene therapy. They also explore the future of gene therapy, including upcoming projects and the broader implications for health and longevity.

Takeaways

✅ Follistatin is a gene therapy known for its anti-aging effects.

✅ Clinical trials showed significant increases in telomere length.

✅ The therapy is administered via a non-invasive injection.

✅ The cost of the therapy is currently set at $25,000.

✅ There are no reported negative side effects from follistatin therapy.

✅ Future projects include Klotho gene therapy, which has potential cognitive benefits.

Chapters

00:00 Introduction to Gene Therapy and Mac's Journey

02:55 Understanding Gene Therapy: Mechanisms and Safety

05:57 The Science Behind Follistatin and Aging

08:58 Real-World Applications and Experiences with Follistatin

12:02 The Process of Receiving Gene Therapy

14:43 Future of Gene Therapy and Upcoming Innovations