This episode is one of our deepest dives ever, into the literature on creatine's effects and tradeoffs with cycling performance, and how the results fare against Kolie's standard for being meaningful, noticeable, or measurable. Because individual studies report such varied results, we instead look at a meta analysis on creatine supplementation in aerobic performance, another on repeated sprints, plus a bonus study with a simulated road race. There's also a brief and explicitly non-expert look at a popular paper on creatine and cognition. Instead of recommending whether cyclists take creatine or not as a binary, we discuss the pros and cons, realistic expectations of effects, and in what cases we would consider supplementation. Plus your listener questions!