This episode explores how combining hormone replacement therapy (HRT) with GLP-1 medications can revolutionize weight management, especially during menopause.

I sit down with Dr. Jason Chiriano to uncover the real story behind using hormone replacement therapy (HRT) alongside GLP-1 medications. We explain why balancing hormones is essential for successful weight loss, for both men and women. And how functional medicine is changing the game from quick fixes to long-term health transformations.

You’ll hear practical advice about combining HRT and GLP-1s, plus real talk about challenges like misinformation on social media, the importance of lifestyle changes, and how to advocate for your own health.

Moments

00:00 GLP Weight Loss Expectations Explained

04:36 Advanced Metabolic Health Strategies

08:03 Future Potential of GLP-1 Drugs

11:18 Weight Loss Medication Insights

14:11 Resistance Training Tips for Beginners

17:11 "Embracing Bad Body Scans"

21:23 One-Year Commitment to Health

24:03 "Consumer Responsibility in Telemedicine"

27:20 "Body Composition Over BMI"

31:00 Insulin Dependency Frustrations in Diabetes

36:05 "Reframing Financial Costs of Problems"

• Hormones and weight loss are deeply connected—GLP-1s work best when combined with proper hormone balance
• Quick-fix deals from telemedicine or med spas often skip critical medical oversight
• Sustainable weight loss involves small, practical lifestyle changes, not radical overhauls
• Coaching, data tracking, and education are huge parts of medical success stories
• Don’t accept being told “it’s all in your head”—trust your body, seek out experts, and invest in your health

5 Frequently Asked Questions about HRT and GLP-1 Therapy

1. What are the benefits of combining HRT with GLP-1 medications?

Pairing HRT with GLP-1 medications can support greater weight loss, reduce inflammation, improve sleep, and help mitigate menopause symptoms, leading to significant improvements in overall health.

2. Who is the ideal candidate for HRT and GLP-1 therapy? Perimenopausal and menopausal women who experience unwanted weight gain, brain fog, poor sleep, or other hormonal symptoms often benefit most, but functional medicine providers individualize based on each patient’s needs.

3. Are GLP-1 medications only for weight loss? No—while FDA approved for weight loss and type 2 diabetes, GLP-1s are showing promise for other conditions like inflammation, cognitive clarity, and reduced cravings, with ongoing research expanding their potential use.

4. How important is lifestyle intervention alongside these medications? Lifestyle changes, such as resistance training, proper hydration, nutrition, and stress management, are essential for maximizing results and sustainable long-term success on HRT and GLP-1s.

5. Is it necessary to stay on GLP-1 medications forever? There is no single protocol; some patients may benefit from long-term low-dose maintenance, while others may wean off. Approaches should be individualized, and more research is emerging on optimal maintenance strategies.

Think of our podcast as your personal weight loss toolbox, filled with the tools you need to build and maintain your health. Whether you're considering GLP-1 medications or looking for holistic weight management strategies, this podcast is designed to empower you with knowledge and support.

Visit my website!

Find me on YouTube

Find me on Instagram @SharonPolsky

https://uppbeat.io/t/matrika/when-we-were-young

License code: 3VR556DKJQFEFZSU

The Weight Loss Decoded - GLP Edition Podcast is for informational and educational purposes only. The content shared here represents the views and opinions of the host and guests and should not be considered medical, health, or professional advice. This podcast is not a substitute for individualized care from qualified medical providers. Please consult with your healthcare provider before making decisions that may affect your health and wellness. Any statements about treatments, health protocols, or medications discussed are based on personal experience or professional expertise and may not be suitable for everyone. Always seek personalized advice from a licensed healthcare professional who understands your specific health needs.

Copyright 2026 Sharon Polsky

Discover why tracking your body composition with BIA scans is crucial when taking GLP-1 weight loss medications like semaglutide.

I sit down with my dear friend Kylie from Evolt360 to talk about something everyone on a weight loss journey should care about: tracking your progress the right way.

We go beyond the scale and dig into why actually monitoring your body composition, especially your muscle mass, is so important, particularly if you're using GLP-1s. Kylie and I share how Evolt360’s BIA scanning technology can give you real feedback that goes far deeper than your weight alone.

We discuss why women (and men!) need to start thinking about muscle much earlier than most of us do, and how strength building isn’t just for bodybuilders—it’s for anyone who wants to age well, stay strong, and feel great.

Throughout our conversation, we unpack how easy, affordable, and empowering it can be to get quality data with a quick scan, and how this information can help you make better choices every step of the way—whether you’re 20, 50, or 91.

Moments

00:00 "Weight Loss Insights with Evolt360"

03:15 "Skeletal Muscle: Key to Health"

08:37 "Teachable Moments in Wellness"

11:15 Protein Intake Recommendations Explained

16:01 "Building Muscle Beyond the Gym"

16:59 "COVID's Impact on Wellness Perspectives"

Here are my top 3 takeaways for anyone pursuing weight loss, especially with GLP-1s:

• Body composition matters more than just your weight. Focusing on muscle mass—not just fat loss—can support long-term health, metabolism, and overall well-being as you age.
• Regular, affordable, non-invasive scanning empowers you with actionable data. Tools like the Evolt360 body scanner, available in over 2,000 US locations, help track progress beyond the scale and support smart, informed adjustments to nutrition and exercise.
• It’s never too late to start building muscle. Whether you’re 20 or 60, resistance training and added protein can dramatically improve quality of life, mobility, and even recovery from illness.

5 Frequently Asked Questions about GLP-1 Weight Loss Tracking

1. What’s the best way to track progress on GLP-1 medications? Use body composition analysis with BIA scanners like Evolt360 to monitor fat, muscle, and water—not just your weight.
2. Do GLP-1 medications cause dangerous muscle loss? While some muscle loss can occur, Sharon Polsky and Kylie Zimmerle explain that severe or dangerous loss is not typical when progress is monitored and muscle-preserving habits are maintained.
3. Is a DEXA scan necessary or affordable for GLP-1 users? No, DEXA scans are costly and primarily measure bone density. BIA scanning is more affordable and provides actionable data on muscle and fat.
4. Why is muscle preservation important during weight loss, especially for women? Building and maintaining muscle boosts metabolism, supports longevity, and prevents age-related muscle wasting, which is especially relevant for women.
5. How can I access an Evolt360 scanner and track my progress? Download the Evolt Active app, set up a profile, and use the location finder to schedule a scan at one of over 2,000 facilities in the US.

Think of our podcast as your personal weight loss toolbox, filled with the tools you need to build and maintain your health. Whether you're considering GLP-1 medications or looking for holistic weight management strategies, this podcast is designed to empower you with knowledge and support.

Visit my website!

Find me on YouTube

Find me on Instagram @SharonPolsky

https://uppbeat.io/t/matrika/when-we-were-young

License code: 3VR556DKJQFEFZSU

The Weight Loss Decoded - GLP Edition Podcast is for informational and educational purposes only. The content shared here represents the views and opinions of the host and guests and should not be considered medical, health, or professional advice. This podcast is not a substitute for individualized care from qualified medical providers. Please consult with your healthcare provider before making decisions that may affect your health and wellness. Any statements about treatments, health protocols, or medications discussed are based on personal experience or professional expertise and may not be suitable for everyone. Always seek personalized advice from a licensed healthcare professional who understands your specific health needs.

Copyright 2026 Sharon Polsky

Discover the real story behind compounding pharmacies, GLP-1 medications, and weight loss safety in this episode with Matt Montes de Oca.

We’re tackling one of the hottest—and most controversial—topics in weight management: compounding pharmacies. To give us the inside scoop, I chat with Matt Montes, Chief Clinical Officer at Strive Pharmacy. Together, we unpack the myths, truths, and realities behind compounding pharmacies, especially when it comes to GLP-1 weight loss medications.

Matt shares his journey into the world of personalized medicine, explains how compounding pharmacies are actually highly regulated, and reveals the rigorous testing and transparency practices that set Strive apart. We talk about patient experiences, how compounding allows for flexible dosing (hello, microdosing GLP-1s!), and why finding your medication sweet spot can be a game changer—whether you’re managing weight, thyroid issues, or more.

We decode the good, the bad, and the ugly. And set the record straight on a new era in weight management!

Moments

00:00 "Compounding Pharmacies: The Truth"

03:54 Origins and Role of Compounding Pharmacies

07:13 Strict Medication Testing Standards

12:33 Finding the Thyroid Medication Sweet Spot

13:40 Microdosing GLP1s for Weight Control

17:08 "Tracking Medication Safety Process"

Here are 3 key takeaways for anyone curious about compounding pharmacies and GLP-1 therapy:

• Compounding Is Highly Regulated: Matt shared that compounding pharmacies like Strive must meet strict standards from state boards, USP requirements, and FDA guidelines—often exceeding these minimums for patient safety.
• Transparency Is Essential: Before choosing any compounding pharmacy, always ask for documentation. You deserve to see proof of potency, safety, and efficacy—from raw ingredients to the finished medication batch.
• Personalization Is a Game Changer: With compounding, patients can fine-tune their doses (like GLP-1 or thyroid meds) in ways big manufacturers simply can’t—leading to fewer side effects and better outcomes.

5 Frequently Asked Questions about Compounding Pharmacy Safety

1. Are compounding pharmacies safe for GLP-1 medications? Yes, compounding pharmacies are highly regulated by state pharmacy boards, USP requirements, and FDA guidance. Strive Pharmacy, for example, conducts third-party testing for every batch and routinely exceeds safety standards.
2. How can I verify the safety and effectiveness of compounded GLP-1s? Reputable pharmacies, like Strive, provide certificates of analysis and third-party test results for potency and sterility. Patients should always request this documentation to ensure quality.
3. What’s the difference between compounded GLP-1s and brand medications? Compounded GLP-1s offer flexible dosing options and can fill gaps during drug shortages. They are prepared under strict safety protocols and allow for personalized treatment that may not be possible with standard brand dosing.
4. Can compounding pharmacies help with medications other than GLP-1s? Absolutely. Compounding pharmacies can provide customized dosing for a wide range of medications, including bioidentical hormones and thyroid medications to help patients find their “sweet spot.”
5. What should I look for when choosing a compounding pharmacy? Look for transparency, willingness to provide documentation, third-party testing, and compliance with state and federal regulations. Consider asking for a tour of the facility to see their procedures firsthand.

Think of our podcast as your personal weight loss toolbox, filled with the tools you need to build and maintain your health. Whether you're considering GLP-1 medications or looking for holistic weight management strategies, this podcast is designed to empower you with knowledge and support.

Visit my website!

Find me on YouTube

Find me on Instagram @SharonPolsky

https://uppbeat.io/t/matrika/when-we-were-young

License code: 3VR556DKJQFEFZSU

Copyright 2026 Sharon Polsky

The Weight Loss Decoded - GLP Edition Podcast is for informational and educational purposes only. The content shared here represents the views and opinions of the host and guests and should not be considered medical, health, or professional advice. This podcast is not a substitute for individualized care from qualified medical providers. Please consult with your healthcare provider before making decisions that may affect your health and wellness. Any statements about treatments, health protocols, or medications discussed are based on personal experience or professional expertise and may not be suitable for everyone. Always seek personalized advice from a licensed healthcare professional who understands your specific health needs.

Struggling with menopausal weight gain? Dr. Cynthia Preston explains hormone changes and how GLP-1s can help you.

I’m joined by Dr. Cynthia Preston, an incredible naturopathic doctor who has dedicated her practice to supporting women through menopause and all the challenges that come with it. Especially weight gain.

Together, we dig into why menopause so often leads to stubborn extra pounds, the science behind it, and why losing muscle and sleep can make things even trickier. We also chat about the powerful role of hormones, why lifestyle interventions still matter, and how GLP-1 medications have become true game changers for women who need extra support on their journey.

• Menopausal weight gain is rooted in biology, not lack of self-control.
• GLP-1 medications, when used with lifestyle interventions, can be a potent tool. Especially when started early.
• Resistance training and prioritizing muscle mass are critical.
• Environmental toxins matter more than you think!
• Every woman’s experience is uniqu. Personalized care, patience, and holistic health are essential.

Moments

00:00 "Motivation for Naturopathic Medicine"

06:04 Hormonal Cycle and Fertility Signals

09:07 "Neuroplasticity and Hunger Hormones"

10:55 Education Overcomes Information Overload

15:38 Estrogen's Impact on Mood and Health

18:27 Fat Cells and Hormones Misunderstood

20:25 Preventive Medicine Advancements

24:15 Maximize Success: Invest in Knowledge

27:12 Balancing Life, Genetics, and Hormones

30:04 "Impact of Xenoestrogens Explained"

33:47 Uncertain Health Outcomes Discussed

39:08 Post-Meal Walk Benefits

5 Frequently Asked Questions about Menopausal Weight Gain

1. Why do women gain weight during menopause? Menopausal weight gain is primarily driven by a loss of estrogen, slower metabolism, loss of muscle mass, and disrupted sleep—all of which make weight management more difficult.
2. How do GLP-1 medications help with menopausal weight loss? GLP-1s help regulate appetite, support fat loss, and can address the biological changes that make weight loss harder during menopause, but work best when combined with lifestyle changes.
3. Is it realistic for menopausal women to expect weight loss? Yes, but success is more likely when addressing hormonal, metabolic, and lifestyle factors rather than relying only on diet or exercise.
4. What are some lifestyle interventions that work alongside GLP-1s? Regular anaerobic exercise, building muscle mass, improving sleep, managing stress, and addressing environmental exposures are key strategies.
5. Can you proactively start GLP-1s before menopause to prevent weight gain? According to Dr. Cynthia Preston, starting proactive interventions—including GLP-1s—before or in the early stages of menopause can help prevent significant weight gain and support overall health.

Think of our podcast as your personal weight loss toolbox, filled with the tools you need to build and maintain your health. Whether you're considering GLP-1 medications or looking for holistic weight management strategies, this podcast is designed to empower you with knowledge and support.

Visit my website!

Find me on YouTube

Find me on Instagram @SharonPolsky

Copyright 2026 Sharon Polsky

https://uppbeat.io/t/matrika/when-we-were-young

License code: 3VR556DKJQFEFZSU

The Weight Loss Decoded - GLP Edition Podcast is for informational and educational purposes only. The content shared here represents the views and opinions of the host and guests and should not be considered medical, health, or professional advice. This podcast is not a substitute for individualized care from qualified medical providers. Please consult with your healthcare provider before making decisions that may affect your health and wellness. Any statements about treatments, health protocols, or medications discussed are based on personal experience or professional expertise and may not be suitable for everyone. Always seek personalized advice from a licensed healthcare professional who understands your specific health needs.

Registered dietitian Stephanie Skeba joins to explain practical nutrition tips specifically for those using GLP-1 weight loss medications.

I sit down with Stephanie Skeba, an experienced registered dietitian, powerlifter, and CrossFit coach with a passion for making nutrition approachable for everyone. Especially those navigating weight loss journeys and GLP-1 medications.

Together, we cut through the biggest nutrition myths, why one-size-fits-all advice just doesn’t cut it, and how social media has made food choices even more confusing.

Stephanie breaks down how to look at your meals through four pillars: quality, quantity, diversity, and timing. We share practical tips for eating well at home and on the go, how to manage sugar and processed foods in your diet, and why fiber—and actually chewing your food—matters so much.

Moments

00:00 "Nutrition Insights with Steph Skiba"

05:18 "Holistic Habits: 1% Improvement"

08:23 "Necessary Processing vs. Junk Food"

11:47 Poor Protein Shakes vs. Steak

13:38 Myth-Busting: Importance of Healthy Fats

17:41 "Women's Unique Nutritional Needs"

19:45 Tracking Body Composition with Evolt

25:01 "Grass-Fed, Nitrate-Free Benefits"

26:41 "Why You Need A Coach"

Steph’s Four Nutrition Keys:

1. Quality: Can you grow it, hunt it, or pick it?
2. Quantity: Are your portion sizes in check?
3. Diversity: Your gut microbiome loves a rainbow—mix up those plants!
4. Timing: Especially for athletes—when you eat matters.

Simple, Doable Hacks:

• Think "1% better" each day. Add a veggie, one more glass of water, or chew your food a little more!
• Flip the old food pyramid—veggies and protein come first, then fats, then fruit, starch, and lastly, sugar.

5 Frequently Asked Questions about GLP-1s and Nutrition

1. Why is protein so important, even if you’re not a bodybuilder? - Protein is essential for muscle health and overall wellness. As Sharon Polsky and Stephanie Skeba explain, everyone—regardless of athletic status—benefits from eating enough protein (02:14).
2. How can I eat less sugar when it’s in so many foods? - Stephanie Skeba recommends reading labels carefully, watching for hidden sugars (including new names like HVHFCS), and focusing on whole foods (“can I grow it, hunt it, pick it?”) (08:33).
3. Is it better to get fiber from supplements or real foods? - Fiber from fruits and vegetables is preferable; real food provides more nutritional benefits and supports healthy digestion compared to fiber supplements (12:00).
4. Are fats really bad for you, or do we need them? - Healthy fats are essential for hormone production and brain health. Skipping fats can lead to neurological issues and does not help with weight management (16:31).
5. What is one easy meal or snack hack for better nutrition on the go - Both Sharon Polsky and Stephanie Skeba recommend portable, balanced snacks like hard-boiled eggs with fruit or grass-fed beef sticks with nuts and fruit (26:08).

Think of our podcast as your personal weight loss toolbox, filled with the tools you need to build and maintain your health. Whether you're considering GLP-1 medications or looking for holistic weight management strategies, this podcast is designed to empower you with knowledge and support.

Visit my website!

Find me on YouTube

Find me on Instagram @SharonPolsky

https://uppbeat.io/t/matrika/when-we-were-young

License code: 3VR556DKJQFEFZSU

Copyright 2026 Sharon Polsky

The Weight Loss Decoded - GLP Edition Podcast is for informational and educational purposes only. The content shared here represents the views and opinions of the host and guests and should not be considered medical, health, or professional advice. This podcast is not a substitute for individualized care from qualified medical providers. Please consult with your healthcare provider before making decisions that may affect your health and wellness. Any statements about treatments, health protocols, or medications discussed are based on personal experience or professional expertise and may not be suitable for everyone. Always seek personalized advice from a licensed healthcare professional who understands your specific health needs.

I talk with Jacqueline Serrao. If you’ve ever felt frustrated, lost, or overwhelmed on your weight loss journey, Jacqueline’s story is a must-listen (and must-read!).

Meet Jacqueline

• Age 41, Long Beach, CA lawyer, devoted cat mom, self-described “shapely woman” with a lifelong love/hate relationship with her weight
• Her weight gain started at 19 and reached an all-time high of 297 pounds in 2022–2023
• After years of yo-yo dieting, stress eating, and feeling like nothing worked, she decided to try a GLP-1 medication (semaglutide)—and everything changed

Why Jacqueline’s Story Matters

Most people assume a medication is just about the number on the scale, but as Sharon and Jacqueline discuss, it’s so much more:

• Food noise gone: GLP-1 helped Jacqueline quiet the constant mental chatter about food. She no longer obsesses over meals or feels anxious about leftovers—something that used to cause her and her husband a lot of (relatable!) stress.
• 58 pounds lost: Jacqueline has gone from 297 to 239 pounds, with significant improvements in her labs and body composition.
• Better mental health: Beyond losing weight, Jacqueline reports less anxiety and better sleep. She even lost her urge to drink alcohol in social settings.
• No more shame: Inspired by her journey, Jacqueline now openly shares her weight and story, encouraging others to let go of secrecy and shame.
• Side effects were manageable: Slight nausea and constipation in the beginning, but “totally worth it.”

Advice from Jacqueline: “Don’t listen to horror stories or clickbait online—talk to an informed professional, get your facts, and see if it’s right for you.”

She also reminds you: it’s ok to use the tools available to you, and there is no shame in seeking support for your health.

Takeaway: Whether you’re just curious about GLP-1s, have struggled with your weight for decades, or are tired of food dominating your thoughts, we hope that Jacqueline’s honesty reminds you: real change is possible.

Moments

00:00 "GLP Weight Loss Journey"

05:42 Metabolism and Weight Loss Challenges

07:45 Breaking Weight Stigma by Sharing

10:35 Food Obsession: A Personal Struggle

14:12 Normalizing GLP1 Conversations

18:10 Consult Professionals, Not the Internet

Think of our podcast as your personal weight loss toolbox, filled with the tools you need to build and maintain your health. Whether you're considering GLP-1 medications or looking for holistic weight management strategies, this podcast is designed to empower you with knowledge and support.

Visit my website!

Find me on YouTube

Find me on Instagram @SharonPolsky

https://uppbeat.io/t/matrika/when-we-were-young

License code: 3VR556DKJQFEFZSU

The Weight Loss Decoded - GLP Edition Podcast is for informational and educational purposes only. The content shared here represents the views and opinions of the host and guests and should not be considered medical, health, or professional advice. This podcast is not a substitute for individualized care from qualified medical providers. Please consult with your healthcare provider before making decisions that may affect your health and wellness. Any statements about treatments, health protocols, or medications discussed are based on personal experience or professional expertise and may not be suitable for everyone. Always seek personalized advice from a licensed healthcare professional who understands your specific health needs.

Copyright 2026 Sharon Polsky

If you’ve ever wondered how GLP-1s fit into real-world women’s health or want strategies for navigating medical conversations, this is a must-listen episode.

I sit down with Dr. Meagan Moore, a leading OBGYN from Orange County, to break down the intersection of women’s health, PCOS, menopause, and GLP-1 medications.

Dr. Moore shares unique insights from her hormone-focused practice, where she regularly helps women struggling with PCOS and menopausal weight gain. Our conversation highlights why PCOS diagnosis is often delayed, how symptoms present differently in each patient, and the real challenges women face when traditional advice like “eat less and move more” simply doesn’t work due to underlying metabolic issues.

Our discussion turns to the science behind PCOS and menopause, explaining how insulin resistance and hormonal changes impact weight and metabolism. Dr. Moore emphasizes the growing role of GLP-1 medications in treating these conditions and why they’re such an effective tool for many patients—though they’re not without their challenges and don’t work for everyone.

You’ll also hear practical tips on how to advocate for yourself when speaking with your doctor, the importance of prioritizing protein and fiber, and how GLP-1s often improve more than just the number on the scale—including joint pain, sleep, and overall quality of life.

Dr. Moore and I bust common myths, address the stigma around medical weight loss, and encourage women not to feel ashamed about seeking effective treatments.

Moments

00:00 PCOS Training Gap in Healthcare

03:27 Challenges in PCOS Diagnosis

08:12 Unresponsive Patients to GLP1 Treatment

10:48 "Long-Term Low Dose Weight Management"

14:48 Reevaluating Tirzepatide 'Nausea' Sensation

17:22 Silencing Food Anxiety

22:29 Consult Your Doctor First

Here are 3 key takeaways that resonated with me:

GLP-1s Offer Real Hope for PCOS & Menopausal Weight Gain: For many women frustrated by traditional weight loss advice, GLP-1 medications have become a game changer, particularly for those with metabolic or hormonal challenges where “calories in, calories out” simply doesn’t work.

Diagnosis Gaps Still Exist: Many women with PCOS go undiagnosed for years, often being told to just “eat less and move more.” Dr. Moore emphasized the importance of seeking providers who truly understand hormonal health when looking for answers—and options.

Advocacy & Education Matter: There’s still stigma and misinformation around medications like GLP-1s. Dr. Moore encourages women not to shy away from conversations about these options. Find practitioners up-to-date with the data, and don’t let shame or insurance roadblocks hold you back from seeking better health.

5 Frequently Asked Questions about PCOS Weight Gain

1. Why is weight gain common for women with PCOS or during menopause?

Hormonal imbalances cause insulin resistance and metabolic changes, making it harder for the body to process food as energy and leading to increased fat storage.

2. Are diet and exercise enough to manage PCOS or menopausal weight gain?

For many women, diet and exercise alone aren’t effective due to underlying metabolic and hormonal issues—a targeted medical approach is often needed.

3. How do GLP-1 medications help with hormone-related weight gain?

GLP-1s address insulin resistance, improve appetite regulation, and support metabolic health, making them an effective tool for women facing hormone-driven weight challenges.

4. What should women do if their doctor dismisses their concerns about weight gain?

Seek out a provider experienced in hormone health who listens, understands the latest treatments, and is open to discussing medications like GLP-1s.

5. What are common side effects of GLP-1 medications and how can they be managed?

Mild nausea and a sense of fullness are common. Starting at low doses, timing injections, staying hydrated, and avoiding alcohol can help minimize side effects.

Think of our podcast as your personal weight loss toolbox, filled with the tools you need to build and maintain your health. Whether you're considering GLP-1 medications or looking for holistic weight management strategies, this podcast is designed to empower you with knowledge and support.

Visit my website!

Find me on YouTube

Find me on Instagram @SharonPolsky

https://uppbeat.io/t/matrika/when-we-were-young

License code: 3VR556DKJQFEFZSU

Copyright 2026 Sharon Polsky

The Weight Loss Decoded - GLP Edition Podcast is for informational and educational purposes only. The content shared here represents the views and opinions of the host and guests and should not be considered medical, health, or professional advice. This podcast is not a substitute for individualized care from qualified medical providers. Please consult with your healthcare provider before making decisions that may affect your health and wellness. Any statements about treatments, health protocols, or medications discussed are based on personal experience or professional expertise and may not be suitable for everyone. Always seek personalized advice from a licensed healthcare professional who understands your specific health needs.

I am bringing you a myth-busting, straight-talking conversation with Dr. Lester Lee, one of the founding fathers of functional medicine and a leading expert in weight loss, hormone therapy, and integrative health.

With so much information—and misinformation—swirling around about GLP-1 medications like Ozempic, Mounjaro, and Wegovy, this episode is all about separating fact from fiction.

Dr. Lee shares his firsthand experience treating patients with GLP-1s, addresses the most common questions and concerns (from side effects to supposed risks), and discusses how real people are seeing changes not just on the scale, but in their overall health and body composition.

You’ll hear us debunk internet rumors, clarify who’s truly a candidate for these medications, and discuss the importance of taking a holistic approach to weight management.

Whether you’re GLP-1 curious, currently on the medication, or just want to stay informed, this episode gives you the science, the stories, and the expert insights you need.

Moments

00:00 GLP1s: Side Effects and Benefits

03:44 GLP Side Effects: Nausea and More

08:54 Maintaining Muscle on GLP Medication

11:30 Self-Titration for Weight Maintenance

15:53 Cost-Effective Compounded Medications

18:01 Alcohol Use and Pancreatitis Risk

22:43 Diabetic Gastroparesis Explained

25:46 Cautious Thyroid Screening Approach

27:53 Comprehensive Health and Lifespan Improvement

Here are 3 key takeaways you should know:

• Most side effects are manageable and not as widespread as reported. While nausea and queasiness can occur at the start, serious outcomes like hospitalization are extremely rare when patients are well supervised and hydrated.
• Sustainable results require a holistic approach. GLP-1s are a tool, not a quick fix. Combining medication with exercise, proper nutrition, hydration, stress management, and good sleep habits yields the best results.
• Personalization matters. Not everyone may need (or should continue) medication long-term. Many patients can maintain weight loss through lasting lifestyle changes, and a careful, thoughtful provider will screen for rare risks and monitor progress closely.

The media loves to focus on extremes, but real patient stories often look much different.

5 Frequently Asked Questions about GLP-1s Side Effects

1. Do GLP-1 medications make you violently ill? - Most people experience only mild nausea or fullness initially, and serious illness is rare with proper dosing and care.
2. Can you lose only muscle (not fat) on GLP-1 medications? - No. With resistance training and adequate protein, patients typically lose body fat—not just muscle.
3. Is hospitalization common for people taking GLP-1 for weight loss? -No, hospitalization due to GLP-1 is extremely rare according to both Sharon Polsky and Dr. Lester Lee's clinical experiences.
4. Do you have to wean off GLP-1 once you reach goal weight? - Not necessarily. Many patients adjust to a maintenance dose or stop, especially if they maintain healthy habits.
5. Are serious risks like thyroid cancer or gastroparesis common with GLP-1? - Serious risks are rare. Media reports focus on potential risks from animal studies or pre-existing conditions; most side effects are mild and manageable.

Think of our podcast as your personal weight loss toolbox, filled with the tools you need to build and maintain your health. Whether you're considering GLP-1 medications or looking for holistic weight management strategies, this podcast is designed to empower you with knowledge and support.

Visit my website!

Find me on YouTube

Find me on Instagram @SharonPolsky

https://uppbeat.io/t/matrika/when-we-were-young

License code: 3VR556DKJQFEFZSU

Copyright 2026 Sharon Polsky

The Weight Loss Decoded - GLP Edition Podcast is for informational and educational purposes only. The content shared here represents the views and opinions of the host and guests and should not be considered medical, health, or professional advice. This podcast is not a substitute for individualized care from qualified medical providers. Please consult with your healthcare provider before making decisions that may affect your health and wellness. Any statements about treatments, health protocols, or medications discussed are based on personal experience or professional expertise and may not be suitable for everyone. Always seek personalized advice from a licensed healthcare professional who understands your specific health needs.

Welcome to Weight Loss Decoded – GLP Edition! I’m Sharon Polsky, your GLP Fact Fairy, and I’m so excited to kick off this podcast by sharing my own story with you.

Just a couple of years ago, I hit menopause at 50 and, despite eating clean and working out six days a week, I watched my weight creep up—and felt all the frustration and confusion that comes with it. That’s when my doctor suggested I try GLP-1 medication, specifically tirzepatide. The results? Life-changing. For the first time since I can remember, food stopped ruling my thoughts, and everything clicked into place.

I quickly realized how much misinformation and stigma surround GLP medications—not just in the media, but even from so-called wellness gurus. I saw so many people, especially women, doubting themselves and feeling ashamed for seeking real solutions outside the usual “just eat less and exercise more” mantra.

That pushed me to launch this podcast: to give you real facts, support, and a community you can trust. Whether you’re here for your health, confidence, or just peace of mind, you deserve the truth.

In every episode, I’ll be bringing on experts—from hormone specialists to menopause pros—to answer your questions and help you navigate GLP-1 medications like tirzepatide, semaglutide, Ozempic, Wegovy, Mounjaro, and Zepbound.

My promise to you: this is a shame-free zone focused on empowerment and facts over fear. Subscribe, share, and join me every two weeks as we decode the myths, bust the stigma, and find support together on this journey.

What You’ll Get from Our Show:

• Honest discussions about GLP-1 medications—debunking myths and sharing the truth.
• Expert insights from amazing guests like Dr. Lester Lee, Dr. Cynthia Preston, Dr. Cheriano, and Dr. Megan Moore, who will cover everything from hormone health to functional medicine and integrating GLP-1s.
• Real talk on battling the stigma, whether you’re using GLP-1s for your health, your confidence, or both (because, honestly—who says you can’t?!).

Copyright 2026 Sharon Polsky

Think of our podcast as your personal weight loss toolbox, filled with the tools you need to build and maintain your health. Whether you're considering GLP-1 medications or looking for holistic weight management strategies, this podcast is designed to empower you with knowledge and support.

The Weight Loss Decoded - GLP Edition Podcast is for informational and educational purposes only. The content shared here represents the views and opinions of the host and guests and should not be considered medical, health, or professional advice. This podcast is not a substitute for individualized care from qualified medical providers. Please consult with your healthcare provider before making decisions that may affect your health and wellness. Any statements about treatments, health protocols, or medications discussed are based on personal experience or professional expertise and may not be suitable for everyone. Always seek personalized advice from a licensed healthcare professional who understands your specific health needs.

https://uppbeat.io/t/matrika/when-we-were-young

License code: 3VR556DKJQFEFZSU