• Tirzepatide is more effective for weight loss than semaglutide.
• Cost-effectiveness is crucial in prescribing weight loss medications.
• Patients with severe obesity should receive more expensive medications for better outcomes.
• Both medications show significant benefits for obesity-related conditions.
• Long-term studies indicate sustained weight loss with both drugs.
• Gender differences affect weight loss outcomes with these medications.
• Safety profiles show tirzepatide may be better tolerated than semaglutide.
• The need for affordable drug pricing is emphasized.
• Clinical benefits extend beyond weight loss to include metabolic health.
• Future studies are needed to confirm cardiovascular benefits of tirzepatide.

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