Biohack-it

I have waited two and a half years to bring you this conversation. Today, I am joined by the world-renowned OBGYN and women’s health expert, Dr. Jessica Shepherd from HERS.

We live in a culture that promises "salvation" through a single shot, a specific pill, or one hormone replacement. But as Dr. Shepherd reveals, the truth about total body optimization is far more complex. This episode is an urgent call for women to reclaim sovereignty over their own bodies and nervous systems.

In this masterclass, we discuss:

The HRT Lie: Why an entire generation of women was taught to fear hormones and the devastating impact of that misinformation.

Total Body Levers: The specific, alternative points of view on medicine that allow you to optimize your health from a cellular level.

Personal Expansion: How to bridge the gap between "getting by" and achieving true longevity.

If you feel like you’ve been looking for answers in all the wrong places, this conversation will give you the tools to finally pull the right levers for your health.

Follow Dr. Jessica Shepherd: Instagram: @jessicashepherdmd

Sponsors:

Rho Nutrition:

I've been using Branch Basics for five years. It changed my health before I even fully understood why.

In this episode I sit down with Allison Love, co-founder of Branch Basics, to break down something most people never think about: the toxic load hiding in your cleaning products, laundry detergent, personal care items and yes, the air inside your own home. We talk about how Allison's co-founder reversed her PCOS not through medication but by changing what she was washing her clothes with. We talk about Marylee, their mentor, whose son went from a healthy, coordinated child to barely being able to lift his head off a pillow after pesticide exposure, and how stripping their home one product at a time brought him back.

We also get into why the word "natural" on a label means nothing, how fragrance hides hundreds of toxic chemicals in a single word, why your sanitizers and disinfectants may actually be making you more vulnerable to getting sick, and what the word "fragrance" is legally allowed to conceal.

I share my own story too. Ovarian cysts since 15. One ovary reconstructed. Migraines. Inflammation. And how switching my environment, not just my diet, changed everything.

Follow Branch Basics: @branchbasics

Sponsors:

Rho Nutrition:

What does it actually take to walk away from a successful career and build something that genuinely fulfills you?

Erika De Pellegrin did exactly that. Corporate lawyer in Australia. New continent. New career. New baby. All of it — on her own terms.

We talked about the moment she realized her job title wasn't her identity, why who you marry is the most important decision you'll make, how she balanced motherhood with building a podcast that blew up, and why women evolve in ways most people never fully account for.

This one is for every woman who has ever asked herself: is this it?

Chapters:

What does it actually take to walk away from a successful career and build something that genuinely fulfills you?

Erika De Pellegrin did exactly that. Corporate lawyer in Australia. New continent. New career. New baby. All of it — on her own terms.

We talked about the moment she realized her job title wasn't her identity, why who you marry is the most important decision you'll make, how she balanced motherhood with building a podcast that blew up, and why women evolve in ways most people never fully account for.

This one is for every woman who has ever asked herself: is this it?

Chapters:

I have been obsessed with frequency medicine since last year, but after sitting down with Henry and Laura from Soaak Technologies, I realized we are only scratching the surface of what’s possible. This isn't "woo-woo"—this is clinical-grade technology currently being used by the U.S. Air Force to optimize pilot performance and mission readiness.

In this episode, we dive into the science of Sympathetic Resonance and how sound frequency compositions can literally turn your "square tires" into round ones. Henry and Laura share the incredible journey of taking these modalities from a high-end clinic in Oklahoma to a global app that is now changing lives in 190 countries.

Try Soaak for yourself:

Go to https://www.soaak.com/biohack-it

(Use code BIOHACKIT for 30 days free!)

Try Branch Basics: 20% off Premium Starter Kit https://branchbasics.com/BIOHACKIT20 Code:Biohackit20

I’ve always been fascinated by the strength of Saudi women, but my conversation with Nada Baeshen went deeper than I ever expected. In this episode of Biohack It, we’re pulling back the curtain on what marriage, divorce, and financial independence really look like in the Middle East—and I’m sharing a massive personal update about my own life.Nada, one of the biggest TV presenters in the Kingdom, opens up about why she preaches financial freedom as the only way for women to truly "take their power back." We discuss the cultural pressure to get married, the fear of "being old" at 32, and the heartbreaking reason she shifted her entire life toward wellness after her father’s dementia diagnosis.Plus, I’m being completely transparent with you guys for the first time: I am going through a conscious uncoupling at 42. We dive into why choosing yourself is sometimes the hardest—and healthiest—biohack you can perform. If you’ve ever felt stuck in a relationship or a career that no longer aligns with your frequency, this masterclass on resilience and starting over is for you.

I finally sat down with the incredible Dr. Natalia Spierings, and she is exactly the kind of pattern-interrupt this industry needs. Natalia isn’t just a UK-trained consultant dermatologist and surgeon—she is also a professional IFBB bodybuilder. Today, we are cutting through the multi-billion dollar marketing hype to get to the "no bullshit" truth about your skin and your body.

In this episode, Natalia exposes why most skincare products are essentially useless and why she believes Vaseline is closer to magic than any luxury serum. We dive deep into the science of Tretinoin, the dangers of long-term fillers (and the "alien" looks they can create), and why fat transfer might be a better surgical alternative for under-eye rejuvenation.

We also discuss the bodybuilding mindset: why most women fail to change their body composition despite lifting weights, and the power of DEXA scanning to keep you accountable. If you’re tired of "hope in a bottle" and want a straightforward, evidence-based approach to longevity and anti-aging, this masterclass is for you.

Connect with Dr. Natalia Spierings:

Instagram: @drnataliaspierings

Sponsors:

Vibrant Wellness: Get the Hormone Zumra test to understand your body’s unique needs. Visit http://vibrant-wellness.com/imanhasan

Chapters:

00:00:00 – Intro

00:01:37 – The Bodybuilding Pivot: From Cycling Accident to the UK Arnold

00:03:55 – The Bodybuilding Mindset in Medicine: Stick to the Basics

00:05:00 – Tretinoin: The Real Gold Standard for Anti-Aging

00:06:48 – The Biggest Skincare Lie: Why Drinking Water Doesn’t Hydrate Skin

00:09:28 – The Danger of Injectables: FDA Approval vs. Efficacy

00:11:00 – Under-Eye Tragedies: Why Fillers Can Block Your Lymphatic System

00:13:38 – Fat Transfer vs. Fillers: A Surgeon’s Take on Volume Loss

00:16:50 – Skincare Scams: Why Peptides and Exosomes are Marketing Gimmicks

00:23:13 – Debunking "Clean" Scams: The Truth About Hydroquinone and Minoxidil

00:25:20 – HRT and Skin: Why Doctors Should Stay in Their Lane

00:30:05 – Botox Myths and the Rise of "Alien" Aesthetic Faces

00:33:32 – Body Composition: Why You’re Not Gaining Muscle

00:35:36 – Knowledge is Power: The Role of DEXA Scanning in Longevity

I have followed Dr. Natalie Crawford for years, and having her on the show is a true full-circle moment for me. As a board-certified reproductive endocrinologist, Natalie is a beacon of knowledge for anyone navigating a fertility journey. In this episode, she gets incredibly raw about her own struggle with infertility and how being gaslit by the medical system led her to discover the "big dirty secret" of reproductive health: inflammation.

We dive deep into the science of ovarian aging and why your "biological clock" is about more than just your age. Natalie explains how mitochondrial health and insulin resistance are the real drivers of egg quality and how you can proactively lower your inflammatory burden through sleep, nutrition, and nervous system regulation. Whether you are considering IVF, egg freezing, or just want to understand your hormones better, this masterclass in preventive care is for you.

In this episode, we discuss:

The connection between chronic stress, cortisol, and fertility loss.

Why building skeletal muscle is the key to fighting insulin resistance.

The truth about forever chemicals (PFCs) in your kitchen and water.

The latest research on Rapamycin and PRP for ovarian longevity.

A step-by-step guide to cycle tracking and identifying ovulation signs.

I have been trying to get Dr. Amy Shah on Biohack-it for 18 months, and we finally made it happen while filming in Riyadh, Saudi Arabia. As two South Asian women, we dive straight into a conversation that hits close to home: why our race is built so petite yet remains at a significantly higher risk for type 2 diabetes, Alzheimer’s, and heart disease than other populations.In this episode, Dr. Amy Shah breaks down the fascinating science of "thrifty genes"—the biological survival mechanism from ancestral famines that makes our bodies hold onto sugar differently. We discuss the "skinny-fat" phenomenon and how modern lifestyle choices, like processed seed oils and a lack of protein, are creating a metabolic crisis. Dr. Shah shares her proprietary 30-3-3 rule for gut health and her signature "cortisol reset" to help you regulate your nervous system and reclaim your energy.Sponsors: Vibrant Wellness: Get the Hormone Zumra test to understand your body’s unique needs. Visit http://vibrant-wellness.com/imanhasan

I’m getting really uncomfortable today. My team told me it was time for "More of Me," so I’m sitting down to answer the questions you sent in on Instagram—nothing is off the table. From my divorce and the move to Dubai to the heartbreaking reason I pivoted my entire career into health and wellness after losing my mother to terminal cancer, this is the most personal I’ve ever been.

We’re diving deep into the biohacking protocols I use to stay high-performing while running two companies. I’m sharing my exact 2026 peptide stack (including BPC-157 and GHK-Cu), the truth about cellular health, and the one supplement I will never live without. We also discuss my life-changing Ayahuasca journey in Mexico and how it helped me find peace with my father's passing. If you’ve ever felt like a victim of your circumstances, I want to show you how to become the hero of your own story through curiosity, accountability, and the right nervous system regulation.

In this episode, we cover:

My move to the Middle East and the future of the UAE.

The "Nesting" method for co-parenting after divorce.

How to spot a "fraud" in the wellness industry.

The science of mitochondria, cortisol regulation, and box breathing.

Sponsors:

Vibrant Wellness: Get the Hormone Zumra test to understand your body’s unique needs. Visit http://vibrant-wellness.com/imanhasan