Normal folate test results may not tell you what the brain actually needs. In this episode of Demystifying PANS/PANDAS, Dr. Richard Frye, a child neurologist, joins us to explain cerebral folate deficiency, why many kids show brain-level need despite normal blood tests, and how targeted folinic acid, dairy elimination, and mitochondrial support can unlock language, calm tics, and steady behavior.

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Think your child’s folate levels are fine? Here’s why that test might be lying to you. In this episode of Demystifying PANS/PANDAS, Dr. Richard Frye shares the fascinating story behind cerebral folate deficiency, how antibodies can block folate from entering the brain, and why so many kids with autism improve with folinic acid (leucovorin). He explains how symptoms shift with age and why some children need more folate, not less.

Dr. Frye then reveals surprising connections: how dairy proteins can block receptors, why certain brands of leucovorin work better, and why ‘normal’ folate tests often mislead. He connects mitochondrial overdrive, nutrient gaps, and prenatal stress, showing parents and practitioners how a step-by-step plan helps children regain focus, energy, and progress.

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Dr. Richard Frye is a Child Neurologist with expertise in neurodevelopmental and neurometabolic disorders. He received an MD and PhD in Physiology and Biophysics from Georgetown University. He completed a residency in Pediatrics at the University of Miami, Residency in Child Neurology and Fellowship in Behavioral Neurology and Learning Disabilities at Harvard University/Children’s Hospital Boston and Fellowship in Psychology at Boston University. He also received a Masters in Biomedical Science and Biostatistics from Drexel University. He holds board certifications in Pediatrics, and in Neurology with Special Competence in Child Neurology. He has authored over 300 publications and book chapters and serves on several editorial boards.

Dr. Frye is a national leader in autism spectrum disorder (ASD) research. He is President and Chief Scientific Officer of the Autism Discovery and Treatment Foundation, Chief Medical Officer of the Neurological Health Foundation, Director of Research and Neurologist at the Rossignol Medical Center and Principal Investigator at the Southwest Autism Research and Resource Center.

He has lead several clinical studies on children with ASD, including studies focusing on defining the clinical, behavioral, cognitive, genetic and metabolic characteristics of children with ASD and mitochondrial disease and several clinical trials demonstrating the efficacy of safe and novel treatments that target underlying physiological abnormalities in children with ASD, including studies on leucovorin, cobalamin and tetrahydrobiopterin and has an ongoing multicenter controlled clinical trial on leucovorin, neuroimmune modulators and photobiomodulation.

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Nancy O’Hara, MD, MPH, FAAP, FMAPS

Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.drohara.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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School closures, masking, and fear left scars. Here's how to rebuild resilience. In this episode of Demystifying PANS/PANDAS, Dr. Elizabeth Mumper joins us to unpack what COVID taught us about children’s health—what worked, what harmed, and how to do better next time. She connects school closures, masking, and fear with developmental and mental health fallout, then ties the virus to neuroinflammation, viral reactivation, mitochondrial dysfunction, and practical ways families can restore resilience.

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Did the lockdowns do more damage to our kids than the virus? In this episode of Demystifying PANS/PANDAS, Dr. Elizabeth Mumper reveals how fear-driven lockdowns and masking policies may have harmed kids more than helped, disrupting emotional growth, learning, and safety nets. She contrasts this with other countries’ child-centered models and exposes how misclassified hospital data exaggerated children’s risk, fueling unnecessary fear.

Dr. Mumper then connects the dots between the virus and PANS/PANDAS, exploring how spike proteins, viral reactivation, and mitochondrial stress can ignite brain inflammation and mood shifts. From the gut-brain connection to the power of vitamins, oxygen, and parental intuition, she lays out a hopeful roadmap: support the mitochondria, question the narrative, and trust your instincts to protect your child’s future.

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Dr. Elizabeth Mumper is the President and CEO of The Rimland Center, where she mentors clinicians dedicated to helping children with neurodevelopmental challenges. She leads two pediatric practices—Advocates for Children, a general pediatrics practice, and Advocates for Families, which focuses on children with autism and related disorders.

A magna cum laude graduate of Bridgewater College, Dr. Mumper earned her medical degree from the Medical College of Virginia and completed her pediatric residency at the University of Massachusetts and the University of Virginia, where she later served as Chief Resident. Her decades-long career includes roles as Director of Pediatric Education for the Lynchburg Family Practice Residency Program, clinical faculty at UVA, and Medical Director of the Autism Research Institute. She currently teaches for MAPS (Medical Academy for Pediatric Special Needs) and Intersect for Kids and serves on the Medical Advisory Board for TACA (Talk About Curing Autism).

Widely recognized for her contributions to pediatric medicine, she has received numerous awards, including Miracle Maker of Central Virginia, Woman of the Year in Health and Sciences, and multiple Inspiring Change Awards from the MINDD Foundation. A respected author and international lecturer, she continues to advance functional and integrative approaches to pediatric care, inspiring clinicians and families across the globe.

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Elizabeth Mumper, MD, IFMCP, FMAPS

LinkedIn: www.linkedin.com/in/elizabeth-mumper-b143022a

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Nancy O’Hara, MD, MPH, FAAP, FMAPS

Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.drohara.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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Before you treat, see the brain. This is why it matters. In this episode of Demystifying PANS/PANDAS, Dr. Eboni Cornish explains how brain scans can help us see and calm the brain inflammation that's messing with mood, sleep, and thinking. She details common root causes (vector-borne infections, mold/biotoxins, strep), the often-missed basics, and practical limbic system retraining tools that make treatment tolerable.

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This scan shows what lab tests often miss—and what to do next. In this episode of Demystifying PANS/PANDAS, Dr. Eboni Cornish joins us to explain how brain scans can reveal inflammation and guide the next steps, from addressing hidden infections and toxins to designing the right therapies. She also describes her two-week intensive program that helps families reset with daily support and clear direction.

She highlights common but overlooked issues—hormones, thyroid, sleep apnea, and gut health—that can stall recovery. She shows how calming an overwhelmed nervous system with limbic retraining makes treatments safer and more effective. Most importantly, she reminds families that there’s hope and real answers beyond standard testing.

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Dr. Eboni Cornish is an integrative and functional medicine physician known for helping patients of all ages uncover and heal the root causes of complex chronic illness. She specializes in autoimmune disease, tick-borne disease, environmental toxicity, gut and neurological imbalances, and uses an evidence-based, whole-body approach to restore health.

At Amen Clinics, Dr. Cornish co-developed the Neuroinflammatory Intensive Program, a two-week immersive reset that combines advanced brain imaging, targeted therapies, and close medical support to help patients with persistent neurological and inflammatory conditions.

Dr. Cornish earned both her undergraduate and medical degrees from Brown University and completed her family medicine residency at Georgetown University. A Howard Hughes Medical Fellow, she conducted research at the NIH with Dr. Francis Collins and now serves as Treasurer of the International Lyme and Associated Diseases Society and is a Fellow of the Institute of Functional Medicine. Recognized as Northern Virginia’s Top Doctor, she’s widely respected for her patient-centered care and dedication to educating clinicians in functional and integrative medicine.

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Eboni Cornish, MD

Website: https://www.amenclinics.com/team/eboni-cornish-md/

Instagram: https://www.instagram.com/dr.ebonicornish/

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Nancy O’Hara, MD, MPH, FAAP, FMAPS

Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.drohara.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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Supporting the nervous system beats punishing behavior. Here’s how. In this episode of Demystifying PANS/PANDAS, Eileen Devine explains Brain First Parenting: a shift from behavior control to supporting a child’s brain and nervous system with empathy, accommodations, and co-regulation. She shows why parent healing and regulation are essential, why traditional behavior plans often fail kids with neuroimmune/neurobehavioral differences, and how families can build resilience day by day.

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It’s not bad behavior—it’s missing brain skills. In this episode of Demystifying PANS/PANDAS, Eileen Devine joins us to explain how what looks like refusal or defiance in kids is often a brain skills gap or a stressed nervous system. Traditional charts, punishments, and rewards usually fail these kids—and exhaust parents.

Instead, she shows how to match expectations to your child’s real abilities, build in supports where skills lag, and use your own calm presence to help them regulate. She also talks about handling unpredictable ‘on/off’ days, the hidden trauma parents carry, and how to stop spiraling about the future. Tune in now to hear practical ways to work with schools, know when an environment isn’t safe, and add small daily habits that build endurance and hope over time.

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Eileen Devine is a parent coach, licensed clinical social worker, and mother to a teenager with neurobehavioral differences. After discovering the neurobehavioral model nearly a decade ago, she transformed her approach to parenting—and now helps other families do the same. She specializes in supporting parents of children with challenging behavioral symptoms, teaching a brain-first approach that builds connection, reduces overwhelm, and restores hope at home.

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Eileen Devine, LCSW

Website: https://www.eileendevine.com/

Instagram: https://www.instagram.com/eileen.devine_brain.first/?hl=en

Facebook: https://www.facebook.com/EileenDevineBrainFirstParenting

Spotify: https://open.spotify.com/show/0yxGMOkvas1wAmojafUWZx

LinkedIn: https://www.linkedin.com/in/eileen-devine-b05638180/

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Nancy O’Hara, MD, MPH, FAAP, FMAPS

Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.drohara.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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When sudden mood swings or rage don’t respond to treatment, infections may be the culprit. In this episode of Demystifying PANS/PANDAS, Dr. Rosalie Greenberg, a child and adolescent psychiatrist, explains how hidden infections can inflame the brain and trigger psychiatric symptoms. She shares real stories, warning signs to watch for, and a practical three-step approach: treat the infection, calm the immune system, and ease symptoms so kids can get their childhood back.

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When parents say something’s wrong, they’re usually right. In this episode of Demystifying PANS/PANDAS, Dr. Rosalie Greenberg shares how many kids once labeled with psychiatric disorders—like bipolar or even schizophrenia—were actually battling hidden infections. She describes dramatic turnarounds, like a teen misdiagnosed with schizophrenia who improved once treated for Bartonella.

Dr. Greenberg explains why some medications (like antidepressants) can backfire in vulnerable kids, and how to use them more safely by starting very low, increasing slowly, and always watching for family history of bipolar disorder. She also notes how ‘psychiatric herx’ reactions during treatment sometimes ease with simple anti-inflammatories. Her bottom line is simple but powerful: be a detective, listen to parents, and never ignore sudden changes in a child’s behavior.

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Dr. Rosalie Greenberg is a board-certified adult, child, and adolescent psychiatrist recognized for her expertise in complex childhood psychiatric disorders and pediatric psychopharmacology. She earned her MD from Columbia University College of Physicians and Surgeons, where she also completed her residency and fellowship, later serving as chief resident and a longtime faculty member.

With over four decades of experience, she has authored books, research articles, and produced educational media addressing topics from adolescent suicide and pediatric bipolar disorder to the psychiatric impact of infections. Practicing in New Jersey, she was among the first to highlight the connection between tick-borne illnesses and psychiatric symptoms in children, often in cases where no tick bite was known. Today, her private practice in Summit, New Jersey, focuses on the psychiatric manifestations of infectious and immune-related diseases in youth, while she continues to lecture nationally and internationally on children’s mental health.

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Rosalie Greenberg, MD

Website: https://www.rosaliegreenbergmd.com/

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Nancy O’Hara, MD, MPH, FAAP, FMAPS

Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.drohara.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/drnancyohara/⁠⁠⁠⁠⁠⁠⁠⁠⁠

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LinkedIn: ⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/nancy-o-hara-md-mph-faap-390781258/⁠⁠⁠⁠⁠⁠⁠⁠⁠

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Fake food, real damage—here’s how to protect your child’s gut and immune system. In this episode of Demystifying PANS/PANDAS, Dr. Michelle Perro joins us to share how ‘fake food’ and environmental toxins are disrupting our kids’ guts and immunity. We also explore practical steps you can start today—from choosing organic staples and cooking at home, to using bone broth, testing key minerals, gardening with kids, and even pushing for healthier school lunches.

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In this episode of Demystifying PANS/PANDAS, Dr. Michelle Perro shares her journey from pediatric emergency medicine to integrative pediatrics after witnessing how homeopathy transformed her own son’s health. She connects the rise of ‘fake food’ with today’s explosion of autoimmunity and neurobehavioral challenges in children. At the heart of her message is the gut microbiome: when chemicals like glyphosate disrupt gut microbes, kids become more vulnerable to inflammation that impacts mood, sleep, learning, and immunity.

Our conversation also turns practical, offering families clear, doable steps. Dr. Perro explains why going organic—especially with dairy, meat, and berries—makes a difference, and how cooking at home, packing lunches, and testing for zinc and magnesium levels can reveal and correct hidden deficiencies. She highlights simple solutions like bone broth, home or community gardening, breastfeeding, and vagal therapies, while also encouraging parents to push for healthier school meals. She ends with hope: even small changes, done consistently, can rebuild resilience and shift a child’s long-term health.

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Dr. Michelle Perro is a pediatrician with over four decades of experience spanning emergency and integrative medicine. She has focused her career on the impact of genetically modified organisms, pesticides, and environmental toxicants on children’s health. She is the co-author of What’s Making Our Children Sick? and serves as executive director of GMO Science, a nonprofit dedicated to evidence-based education on food and health. She also sits on the Scientific Advisory Board for Biocidin Botanicals. A sought-after speaker on regenerative food, soil, and environmental justice, she continues to champion children’s health worldwide.

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Michelle Perro, MD, DHom

Website: https://gmoscience.org/

X: https://x.com/GMOScience

Facebook: https://www.facebook.com/GMOScience

Instagram: https://www.instagram.com/drmichelleperro/

LinkedIn: https://www.linkedin.com/in/michelle-perro-md-2593ba9/

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Nancy O’Hara, MD, MPH, FAAP, FMAPS

Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.drohara.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/drnancyohara/⁠⁠⁠⁠⁠⁠⁠⁠

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LinkedIn: ⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/nancy-o-hara-md-mph-faap-390781258/⁠⁠⁠⁠⁠⁠⁠⁠

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These moms turned heartbreak into hope—and created a movement that’s changing lives. In this episode of Demystifying PANS/PANDAS, Jennifer Vitelli and Cathy Witkos join us to share how the Look. Foundation is tackling PANS/PANDAS through the three pillars of support, education, and awareness. From over $400,000 in healing grants to nationwide school outreach, we outline practical ways families can find help, community, and hope.

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In this episode of Demystifying PANS/PANDAS, we sit down with the co-founders of the Look. Foundation, Jennifer Vitelli and Cathy Witkos to trace their journeys from isolated parents to movement-builders. They outline their foundation’s three pillars—support, education, and awareness—and share what that looks like on the ground: over $400,000 in healing grants, regular group calls that connect families across the country, and practical resources that shorten the learning curve and end isolation.

We also address common misconceptions and emphasize early detection: when kids experience abrupt behavioral changes, families and clinicians should look for medical triggers and document symptoms, while partnering with schools to connect the dots. The conversation highlights bold awareness campaigns and a long-term strategy to make access equitable, expand grants, and build a national infrastructure so no child with PANS/PANDAS is overlooked or left behind.

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Jennifer Vitelli serves as the executive director of the Look. Foundation, where she helps children and young adults affected by infection-triggered neuroinflammatory disorders like PANS/PANDAS. She has co-led and co-founded the Massachusetts Coalition for PANS/PANDAS Legislation, achieving key legislative wins. Jennifer was also a founding board member of the New England PANS/PANDAS Association.

Cathy Witkos is the president of the Look. Foundation and has been a leading advocate in the PANS/PANDAS community. She is a mother of three (one child healing from PANS/PANDAS) and has helped build support networks and awareness from the ground up. Cathy was a founding board member of the New England PANS/PANDAS Association and has spearheaded efforts in community education, school and nurse outreach, public awareness, and financial grant support for families facing this often misunderstood illness.

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Website: https://www.lookfoundation.org/

Facebook: https://www.facebook.com/LookFoundation

Instagram: https://www.instagram.com/look.foundation/

LinkedIn: https://www.linkedin.com/company/look-foundation-inc/

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LinkedIn: ⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/nancy-o-hara-md-mph-faap-390781258/⁠⁠⁠⁠⁠⁠⁠

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Could something as simple as your child’s breathing be affecting their behavior? In this episode of Demystifying PANS/PANDAS, Drs. Lynda and Krystle Dean-Duru join us to explain how our breathing patterns shape sleep, immunity, and behavior in our children. We also delve into various aspects, such as birth factors, breastfeeding, nasal hygiene, and chewing, all aimed at reducing inflammation and promoting healing.

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In this episode of Demystifying PANS/PANDAS, we explore the tight link between airway health, craniofacial development, and systemic inflammation in children. Drs. Lynda and Krystle Dean-Duru join us to trace patterns from birth to early feeding, showing how breastfeeding and chewing help the jaws widen, the palate lower, and the nose open for efficient nasal breathing. They emphasize that mouth breathing bypasses filtration and nitric oxide, strains the brain and body, and reinforces sympathetic overdrive that impairs sleep and healing.

They also outline a practical integrative toolkit that includes nasal hygiene to support lip seal as well as whole foods and posture for growth. Their message is hopeful: start as early as infancy when possible, but it’s never too late to improve airway, sleep, and overall health.

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Dr. Lynda Dean-Duru and Dr. Krystle Dean-Duru are a pioneering mother–daughter team transforming pediatric dentistry with an integrative, airway-centric approach. Together at Ashburn Children’s Dentistry, they combine laser-assisted therapies, myofunctional training, and growth-guidance appliances to optimize craniofacial development, sleep, and breathing from infancy through adolescence. Their shared mission is to empower families with early, preventative strategies that transform oral health, airway function, and overall health

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Website: https://www.kidzsmile.com/

Facebook: https://www.facebook.com/AshburnChildrensDentistry/

Instagram: https://www.instagram.com/ashburnchildrensdentistry/

LinkedIn: https://www.linkedin.com/in/ashburn-childrens-dentistry-60a63537/?trk=public_profile_browsemap

YouTube: https://www.youtube.com/channel/UCGrgxoVVrQRf6je6H_OkkDw

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Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.drohara.com⁠⁠⁠⁠⁠⁠⁠⁠⁠

Facebook: ⁠⁠⁠⁠⁠⁠https://www.facebook.com/drnancyohara/⁠⁠⁠⁠⁠⁠

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LinkedIn: ⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/nancy-o-hara-md-mph-faap-390781258/⁠⁠⁠⁠⁠⁠

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At NutraMedix, our mission is to address complex health challenges by supporting medical professionals and their patients with the highest quality nutraceuticals, education, and service.

With over 30 years of experience in the nutraceutical industry, we have earned a trusted reputation among healthcare practitioners worldwide.

We take a holistic approach to every step of our process from sourcing and formulation to scientific validation and sustainability. Our goal is to provide products that support not only individual health but also economic, social, spiritual, and environmental well-being.

By combining traditional wisdom with modern science, NutraMedix ensures that every product is crafted with the highest quality standards, offering practitioners safe, effective, and reliable solutions for patient care.

We collaborate with healthcare professionals to create targeted solutions that support a wide range of health challenges. Our unique supplements, including our signature liquid extracts, are designed to optimize absorption and effectiveness. Many of our products have been used in clinical settings and are trusted by practitioners for their reliability and results.

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Website: ⁠⁠⁠https://www.nutramedix.com/pages/practitioners⁠⁠⁠

15% Discount Code: AVEATALKS

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Lyme disease wears many disguises. In kids, it can look like anxiety, depression, and even tics, symptoms also common for PANS/PANDAS. In this episode of Demystifying PANS/PANDAS, Dr. Jaquel Patterson joins us to unpack how infections, a leaky blood–brain barrier, hormones, sleep, and nutrients interact. She also unveils what lifestyle, botanicals, and targeted testing can do to support recovery.

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What if your child’s tics were rooted in an infection no one’s testing for? In this episode of Demystifying PANS/PANDAS, Dr. Jaquel Patterson joins us to share her clinical journey from personal diagnosis to treating complex tick-borne illness. She explains how chronic inflammation weakens the blood–brain barrier, activates microglia, and disrupts brain regions to fuel anxiety, depression, cognitive symptoms, and tics in kids.

Dr. Patterson talks about botanicals with antimicrobial and anti-inflammatory actions, including stevia and cordyceps. She also discusses hormone considerations in adolescents and women, mold’s impact, and the need for individualized testing, realistic relapse planning, and steady advocacy toward full recovery. Watch the full episode to gain insights and discover practical strategies you can use today to protect brain health, calm inflammation, and support lasting recovery.

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Dr. Jaquel Patterson is a naturopathic physician and bestselling author with almost a decade of clinical expertise. She is the founder of Fairfield Family Health, where she specializes in tick-borne infections, autoimmune conditions, integrative psychiatry, autism spectrum disorder, allergies, and environmental medicine. Inspired by her mother’s struggle with lupus and her own journey overcoming tick-borne infections, she blends professional expertise with personal experience to provide compassionate, root-cause care. She is the author of Women and Lyme: An Integrative Guide to Better Health and a frequent speaker and trainer for healthcare providers worldwide. A past president of the American Association of Naturopathic Physicians and current treasurer of the American Academy of Environmental Medicine, her work has been featured in Forbes, USA Today, New York Magazine, CBS, NBC, and ABC.

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Website: ⁠⁠⁠⁠⁠⁠⁠⁠https://www.drohara.com⁠⁠⁠⁠⁠⁠⁠⁠

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Could planning before pregnancy reduce your child’s risk of chronic illness? In this episode of Demystifying PANS/PANDAS, functional medicine dietitian Vicki Kobliner joins us to talk about her Healthy Baby Roadmap program. Discover how preconception planning, critical nutrients like iodine and choline, and simple lifestyle steps can give your child the best start in life and help lower the risk of chronic illness.

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In this episode of Demystifying PANS/PANDAS, we welcome functional medicine dietitian Vicki Kobliner to explore how parents can give their children the best start in life through her program, Healthy Baby Roadmap. Vicki explains why preconception planning is critical, emphasizing the importance of nutrients like iodine, choline, and methyl folate, along with safe fish consumption and reducing environmental toxins. She also shares practical steps for gut health, lifestyle support, and navigating pregnancy tests and birth planning with confidence. This empowering conversation offers hope to parents who want to reduce their child’s risk of chronic illness through informed, proactive choices.

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Vicki Kobliner is a registered dietitian and certified nutrition specialist with decades of experience in integrative and functional nutrition. She is the founder of Holcare Nutrition, where she specializes in supporting children and adults with complex chronic illnesses.

Vicki partners with families to create personalized nutrition and lifestyle plans that address root causes and promote lasting healing. She is a frequent lecturer, educator, and advocate, dedicated to helping patients optimize their health through the power of nutrition, functional testing, and integrative care.

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Website: https://holcarenutrition.com/

Facebook: https://www.facebook.com/vkobliner

Instagram: https://www.instagram.com/holcarenutrition/

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