I get asked about fish oil all the time. And I understand why. One study says it saves lives. Another says it does nothing. Some people swear by it. Others call it useless. So in this episode, I wanted to slow everything down and ask a simpler, more honest question: do you actually need fish oil—and if you do, how much makes sense for you?

I walk through the trial that made omega-3s famous again, the one that showed real cardiovascular benefit with a high-dose, EPA-only prescription product—and then explain why other large trials, using different formulations, showed no benefit at all. This is where most of the confusion lives, and it turns out the details really matter.

We break down what omega-3s actually are (and why “fish oil” isn’t one thing), the differences between ALA, EPA, and DHA, and what they really do inside the body. I explain when omega-3s are essential, when they’re conditionally helpful, and when adding more likely won’t change anything.

I also talk about blood testing—what an Omega-3 Index can tell you, what it can’t, and how to use testing without over-interpreting it. We cover heart disease, triglycerides, pregnancy, brain health, mood, dry eyes, autoimmune conditions, plant-based diets, algae-based omega-3s, krill oil, and why supplement labels are often misleading.

And because this isn’t a wellness trend conversation, we also talk about risk—atrial fibrillation, bleeding, dose, and when omega-3s should be treated like a medication decision, not a harmless habit.

This episode isn’t about convincing you to take another supplement. It’s about helping you stop guessing. If you’ve ever stood in the supplement aisle—or stared at a lab result—wondering whether fish oil actually belongs in your life, this conversation will give you the framework to decide.Dr. Marbas Substack: https://drlauriemarbas.substack.com/

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