Biohacking Beauty: The Anti-Aging Skincare Podcast

Dr. Jessica Shepherd: The Shocking Truth About Menopause & Skin Aging (Most People Get This Wrong!)


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Most people think menopause is just about hot flashes and mood swings—but what if I told you it’s actually one of the biggest drivers of skin aging? From collagen loss to increased sensitivity, breakouts, and inflammation, hormonal shifts can make you look older, faster. And yet, no one is talking about it.

To uncover the real impact of menopause on skin health (and what you can do about it), I’m joined by Dr. Jessica Shepherd, an OB-GYN, menopause expert, and founder of Sanctum Med & Wellness. She’s on a mission to rewrite the menopause narrative, showing women how to take control of their skin, hormones, and longevity.

In this episode, we dive into the real impact of estrogen decline on skin aging, why some women experience sudden breakouts or rosacea in midlife, and how hormone replacement therapy (HRT) can play a role in both skin health and longevity. We also explore the connection between gut health, inflammation, and skin vitality, as well as the cutting-edge treatments and biohacking strategies that are changing the game for menopausal women.

Dr. Shepherd is also the author of Generation M, a book that serves as both a medical and lifestyle guide for women navigating this stage of life. She breaks down why menopause isn’t just a phase, it’s a long-term shift that requires a strategic approach to aging well.

If you’re looking for science-backed strategies to optimize your skin, hormones, and overall well-being through perimenopause and menopause, this episode is a must-listen.

We Also Discuss:

(00:02) Women's Health and Skin Aging

(09:31) Hormone Therapy and Skin Rejuvenation

(17:29) Effective Skincare Ingredients and Approaches

(21:46) Longevity and Gut Health for Skin

(31:42) Importance of Sleep for Longevity

(39:08) Future of Women's Health Therapies

(52:16) Embracing Aging With Agency and Curiosity

Learn more about:


Young Goose


  • Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/   
  • Instagram: @young_goose_skincare


Dr. Jessica Shepherd


➡️ Exclusive for Biohacking Beauty Listeners

If you’re serious about optimizing your skin health and hormones, here’s something special for you: Anyone who visits Dr. Jessica Shepherd’s clinic, and mentions the Biohacking Beauty Podcast will receive a complimentary skin consultation.

  • Instagram: @jessicashepherdmd
  • Twitter: @JShepherd_MD
  • LinkedIn: Jessica Shepherd, MD, MBA, FACOG
  • Book: Get Dr. Jessica Shepherd’s Book Generation M

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Biohacking Beauty: The Anti-Aging Skincare PodcastBy Young Goose

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