Why hypothyroidism is not the root cause of your issues

Why TSH on its own is not a good marker of thyroid status

The importance of thyroid hormones for sex hormone production, gut health, and immune function

T3’s effects on autophagy, mitochondrial biogenesis, and uncoupling

Whether low thyroid activity is beneficial for longevity and aging and when a high TSH may be a good sign

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Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-95-hypothyroidism-in-context-thyroid-hormone-basics-hypothyroidism-part-1/ 

Timestamps:

0:00 – intro 

1:19 – an introduction to hypothyroidism and common symptoms of hypothyroidism

9:02 – the broader biological context of hypothyroidism and hypothyroidism as a low metabolic state 

12:45 – why hypothyroidism is not the root cause

16:23 – the basics of the different thyroid hormones and their regulation

19:54 – the hypothalamic-pituitary-thyroid axis and the nuances within the negative feedback loops

24:45 – the basics of thyroid hormone production

29:37 – the basics of thyroid hormone conversion

35:17 – the larger context of thyroid hormone production and conversion

38:58 – the basics of thyroid hormone transport  

41:44 – the basics of thyroid hormone uptake

46:23 – the nutrients involved in thyroid hormone production and conversion

50:26 – the cellular effects of T3 (metabolic stimulation, uncoupling, autophagy, mitochondrial biogenesis, steroidogenesis from cholesterol)

57:29 – the effects of T3 on gut health, immune function, and aging

1:03:08 – whether low thyroid activity is beneficial for longevity and aging and when a high TSH may be a good sign

1:08:41 – the relationship between vitamin A and thyroid hormones