Extend Your Healthspan through Cellular Optimization with Dr. Will Haas: Rational Wellness Podcast 459 Longevity and Healthspan: Cellular Optimization, Toxins, Testing, and Peptide Therapies with Dr. Will Haas Dr. Ben Weitz introduces the Rational Wellness Podcast and interviews Dr. Will Haas, founder of VYVE Wellness, about longevity as extending healthspan and maintaining function rather than simply living longer. They discuss preventable lifestyle risk factors behind chronic disease, major blind spots in conventional medicine (limited insurance-driven labs and reference-range thinking), and the value of deeper functional testing, including advanced cardiometabolic markers, toxins (heavy metals and mycotoxins), and gut health. Haas describes urine testing (Real Time Labs, Vibrant America), detox strategies, and therapeutic plasma exchange as a more aggressive option. He highlights body composition and heart rate variability as key assessments and reviews core lab categories (metabolic, inflammation, hormones, micronutrients, detoxification). They cover biological aging methylation tests, underused labs like fasting insulin and oxidized LDL, personalized diet interventions, peptide therapies (growth hormone secretagogues, tesamorelin, mitochondrial peptides), NAD strategies, limited use of senolytics, and the importance of hormone optimization and emerging omics such as metabolomics. 00:00 Show Intro 01:00 Meet Dr Will Haas 02:00 Longevity Defined 03:25 Lifestyle Risk Factors 05:16 Conventional Blind Spots 08:16 Advanced Cardio Markers 10:38 Toxins And Aging 13:17 Testing For Toxins 14:31 Therapeutic Plasma Exchange 17:55 Patient Workup Basics 19:43 HRV And Lab Strategy 24:10 Biological Age Testing 24:45 Sponsor Apollo Wearable 26:14 Underused Key Labs 28:10 Interventions Foundations 28:47 Clean Eating Defined 29:16 Gut Bloating and SIBO 29:59 Personalized Diet Strategy 30:51 Peptides and FDA Debate 32:41 Growth Hormone Controversy 34:23 Why Peptides Feel Safer 37:49 Choosing GH Peptides 40:09 GLP-1 Muscle Loss Fixes 42:30 Mitochondria and Energy 45:01 NAD Precursors and Sirtuins 47:37 Brain Health and Hormones 51:54 Longevity Myths and Methylene Blue 53:23 Future of Omics Testing 55:42 Final Takeaways and Contact

Dr. Will Haas, MD, MBA is redefining what it means to age well. He is the Founder and CEO of VYVE Wellness in Charlotte, NC, where he helps high-achieving professionals reclaim energy, focus, and vitality through cellular optimization. Dr. Haas can be reached through his website VYVEWellness.com

Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure. Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111.