Dr. Leonard Weinstock discusses Innovative Solutions for Mast Cell Activation Syndrome with Dr. Ben Weitz.

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Understanding Mast Cell Activation Syndrome with Dr. Leonard Weinstock In this episode of the Rational Wellness Podcast, Dr. Ben Weitz and guest Dr. Leonard Weinstock explore Mast Cell Activation Syndrome (MCAS), its symptoms, and diagnosis. Dr. Weinstock, an expert in internal medicine and gastroenterology, explains the challenges of diagnosing MCAS, the importance of recognizing overlapping conditions like Ehlers-Danlos syndrome and POTS, and the role of chemical mediators. He shares insights into the condition's impact on various systems, discusses diagnostic tests, and detailed treatment protocols including the use of antihistamines, low-dose naltrexone, and diets. The discussion also delves into the story of Dr. Weinstock's grandson's battle with MCAS, and ends with considerations for managing related conditions and further educational resources. 00:00 Introduction to the Rational Wellness Podcast 00:26 Understanding Mast Cell Activation Syndrome 01:42 Symptoms and Misdiagnosis of MCAS 02:36 Dr. Weinstock's Expertise and Research 03:14 Identifying MCAS in Patients 06:50 Common Symptoms and Triggers of MCAS 18:55 Diagnosing MCAS: Tests and Challenges 27:35 Managing and Treating MCAS 35:50 Introduction to Multiple Chemical Sensitivities 36:52 Understanding Alpha Gal Syndrome 37:55 Exploring TILT and Mast Cell Activation 38:53 Diagnosing and Treating Alpha Gal Syndrome 40:17 Mast Cell Activation Syndrome Treatments 43:53 Case Study: Mold Exposure and Neural Retraining 45:45 Dietary Strategies for Mast Cell Activation Syndrome 47:25 Ehlers-Danlos Syndrome and Mast Cell Activation 49:47 Personal Story: Treating Max's Mast Cell Activation 54:25 The Importance of Recognizing Mast Cell Activation Syndrome 54:58 Documentary on Stealth Syndromes 01:02:14 Contact Information and Resources 01:05:07 Conclusion and Podcast Sign-Off

Dr. Leonard Weinstock is Board Certified in Gastroenterology and Internal Medicine, practicing in St. Louis, Missouri. He is president of Specialists in Gastroenterology and the Advanced Endoscopy Center. He teaches at Barnes-Jewish Hospital and is an Associate Professor of Clinical Medicine and Surgery at Washington University School of Medicine. Dr. Weinstock is an active lecturer, including having spoken at some SIBO conferences, and he has published more than 70 articles, editorials, and book chapters. He has teamed with Dr. Lawrence Afrin to research and publish articles on Mast Cell Activation syndrome and gastroenterology. His contact info is at Specialists in Gastroenterology and his phone is 314-997-0554.

Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure. Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111.

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Dr. Peter Bongiorno discusses Natural Solutions for Depression and Anxiety with Dr. Ben Weitz.

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An Integrative Approach to Managing Depression and Anxiety with Dr. Peter Bongiorno In this episode of the Rational Wellness Podcast, Dr. Ben Weitz talks with Dr. Peter Bongiorno, a naturopathic doctor and acupuncturist, about an integrative approach to treating depression and anxiety. They explore how conventional treatments often fail to address underlying issues and discuss the potential benefits of functional medicine. The conversation covers dietary recommendations, the role of neurotransmitters, and the use of various supplements and lifestyle changes to support mental health. They also touch on the significance of vagal nerve tone, the impact of social media, and the importance of personalized patient care. 00:00 Introduction to the Rational Wellness Podcast 00:30 Understanding Depression and Anxiety 01:33 Meet Dr. Peter Bongiorno 02:23 The Integrative Approach to Mood Disorders 07:30 The Role of Neurotransmitters 16:47 Diet and Mood Disorders 18:46 The Mediterranean Diet Explained 22:33 Alcohol and Coffee: Effects on Mood 26:46 Low Carb and Ketogenic Diets 29:05 Product Spotlight: The Apollo Wearable 29:56 Benefits of Apollo Neuro 30:36 Key Lab Tests for Patients 33:56 Importance of Sleep 34:44 Supplements for Sleep 35:54 Nutritional Supplements for Depression and Anxiety 41:57 The Role of Lithium in Mental Health 46:50 Impact of Social Media on Mental Health 49:24 Vagus Nerve and Mental Health 52:28 Final Thoughts and Contact Information

Dr. Peter Bongiorno is a Naturopathic Doctor and Acupuncturist and he is the co-director of InnerSource Natural Health and Acupuncture, with offices in New York City and on Long Island. He also works with clients around the world via phone or Zoom. Dr. Bongiorno did research at the National Institutes of Health in the department of Neuroimmunology and then went to Bastyr University to study naturopathic medicine and acupuncture. He wrote a number of books, including Healing Depression in 2010 and Holistic Solutions for Anxiety and Depression in 2015, both targeted for physicians, as well as How Come They're Happy and I'm Not, and Put Anxiety Behind You: The Complete Drug Free Program. His website is DrPeterBongiorno.com.

Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure. Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111.

Dr. John Douillard discusses Ayurvedic Longevity with Dr. Ben Weitz.

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Dr. John Douillard is a globally recognized leader in natural health, Ayurveda, and sports medicine. Dr. Douillard is the founder of LifeSpa.com, one of the most popular Ayurvedic health resources online, and the author of seven books, including Body, Mind, and Sport, The 3-Season Diet, and Eat Wheat. He has also served as the Director of Player Development for the New Jersey Nets, where he helped professional athletes use Ayurvedic principles to enhance performance and recovery. Dr. Douillard now directs the LifeSpa Ayurvedic Clinic in Boulder, Colorado, where he integrates ancient Ayurvedic wisdom with cutting-edge modern science. His website is LifeSpa.com.

Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure. Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111.

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Dr. Matthew Budoff discusses Preventative Cardiology with moderator Dr. Ben Weitz at the Functional Medicine Discussion Group meeting on September 25, 2025. This was the second annual Dr. Howard Elkin memorial Preventative Cardiology lecture.

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Functional Medicine, Preventative Cardiology, and the Latest in Supplement Research with Dr. Matthew Budoff In this episode of the Rational Wellness Podcast, Dr. Ben Weitz discusses the latest advancements in functional medicine and preventative cardiology. He hosts Dr. Matthew Budoff, a preventative cardiologist and published researcher, to delve into heart scans, the significance of lipids, and alternative therapies for managing cardiovascular health. Dr. Budoff covers a range of topics including the benefits of Bempadoic acid, the impact of testosterone on heart disease, the efficacy of fish oils, and the potential of aged garlic extract for slowing coronary calcium progression. They discuss studies on red rice yeast, citrus bergamot, and the mechanisms of various supplements in managing cholesterol and reducing cardiovascular risks. The episode also touches on the implications of iron and nitric oxide levels on heart health. 00:00 Introduction to the Rational Wellness Podcast 00:26 Functional Medicine Discussion Group Overview 01:40 Remembering Dr. Howard Elkin 02:10 Introduction to Dr. Matthew Budoff 02:30 Understanding Cardiovascular Scans 03:04 The Importance of Lipids in Cardiovascular Health 05:46 Alternative Lipid-Lowering Therapies 12:13 The Role of EPA in Cardiovascular Health 21:13 Testosterone and Cardiovascular Risks 25:59 Garlic Supplements for Heart Health 33:51 Garlic's Impact on Calcium Regression 34:08 Dosage and Tolerance of Garlic Supplements 35:10 Clinical Trials and Blood Pressure Benefits 36:30 Historical and Modern Uses of Garlic 37:06 Comparing Garlic Forms and Consistency 41:15 Red Yeast Rice and Its Benefits 47:08 The Role of Niacin and Other Supplements 49:12 Chelation Therapy and Other Treatments 49:40 The Importance of Prevention in Cardiology 50:19 Endothelial Health and Natural Compounds 53:00 CT Angiograms and Plaque Analysis 01:00:11 Iron Levels and Heart Disease 01:02:22 Conclusion and Podcast Information

Dr. Matthew Budoff is a professor of medicine at the David Geffen School of Medicine at UCLA, Program Director and Director of Cardiac-CT, Division of Cardiology, Harbor-UCLA Medical Center and he is an investigator with The Lundquist Institute https://lundquist.org/matthew-budoff-md. Dr. Budoff's research is devoted to advancing procedures that can help doctors identify patients early that are at high-risk for cardiac events and progression of atherosclerosis. This early detection can lead to patients being placed on the correct therapeutic path to prevent a heart attack. Additionally, Dr. Budoff's research focuses on determining the effect of different therapies on atherosclerosis and determine if heart disease can be reversed. His office is in Torrance, California and his office number is 310-222-2773.

Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure. Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111.

View the Show Notes For This Episode

Dr. Maria Sophocles discusses The Musculoskeletal Syndrome of Menopause with Dr. Ben Weitz.

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Podcast Highlights

Understanding the Musculoskeletal Syndrome of Menopause with Dr. Maria Sophocles on the Rational Wellness Podcast In this episode of the Rational Wellness Podcast, host Dr. Ben Weitz discusses the musculoskeletal syndrome of menopause with Dr. Maria Sophocles, a board-certified OBGYN specializing in women's health. The conversation covers how the drop in estrogen levels during menopause significantly impacts muscles, bones, joints, and connective tissues, leading to increased risks of musculoskeletal pain, sarcopenia, osteopenia, and osteoarthritis. The discussion also explores the importance of hormone replacement therapy, the role of estrogen as an anti-inflammatory and anabolic hormone, and the necessity of strength training in mitigating the effects of menopause. Dr. Sophocles also touches on related topics like heart disease, the timing hypothesis for hormone therapy, and practical steps women can take to maintain their musculoskeletal health. 00:00 Introduction to the Rational Wellness Podcast 00:40 Guest Introduction: Dr. Maria Sophocles 02:20 Understanding Menopause and Hormones 05:53 Musculoskeletal Syndrome of Menopause 08:11 The Role of Estrogen in Joint and Muscle Health 11:56 Hormone Replacement Therapy: Benefits and Controversies 22:49 Strength Training and Sarcopenia Prevention 34:56 Conclusion and Final Thoughts __________________________________________________________________

Dr. Maria Sophocles is a board-certified OB/GYN who specializes in women's health across the lifespan. She is the Medical Director of Women's Healthcare of Princeton www.princetongyn.com and she is the author of a forthcoming book, "The Bedroom Gap," on sex in midlife. Dr. Sophocles is also the CMO of EMBR Labs, a Boston-based wellness device company EMBRLabs.com.

Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure. Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111.

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Craig Mullen discusses Root Cause Medicine with Dr. Ben Weitz.

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Podcast Highlights

Understanding Functional Medicine and Peptides with Craig Mullen In this episode of the Rational Wellness Podcast, Dr. Ben Weitz interviews Craig Mullen, a nurse practitioner and the founder of Remedy Functional Health Solutions. They discuss the functional medicine approach to health, focusing on the importance of understanding root causes rather than just treating symptoms. The conversation delves into the significance of detailed testing, including advanced lipid profiles and full thyroid panels, to provide a more comprehensive view of a patient's health. Craig shares his journey into nursing and functional medicine, the challenges with current healthcare practices, and his experience and insights on the use of GLP-1 peptides like Semaglutide for weight loss and other health benefits. They also explore the potential benefits of peptides like BPC 157 and SS-31 for tissue repair and mitochondrial health. Finally, Craig provides practical advice for patients and underscores the importance of working with trained healthcare providers for peptide therapy. 00:27 Meet Craig Mullen: Functional Medicine Advocate 01:45 Craig Mullen's Journey to Becoming a Nurse Practitioner 05:49 The Importance of Functional Medicine 07:56 Challenges in Conventional Medical Testing 13:07 Understanding Hashimoto's Thyroiditis 17:00 The Role of Progesterone in Thyroid Health 19:28 Advanced Lipid Profiles: Why They Matter 27:07 Nutritional Approaches to Lowering Lipoprotein A 28:51 Exploring Lipid Profiles and Omega-3s 30:13 Understanding HDL and Its Role 32:40 The Rise of GLP-1 Peptides 36:16 Effective Use of GLP-1 Medications 44:03 The Benefits and Risks of Peptides 49:59 Final Thoughts and Contact Information ________________________________________________________

Craig Mullen is a nurse practitioner and he is the founder and medical director of Remedy Functional Health Solutions, which is located in Salisbury, Maryland and his phone is 443-342-4141.

Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure. Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111.

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Kirsten Karchmer discusses Improving Fertility Naturally with Dr. Ben Weitz.

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Podcast Highlights

Enhancing Natural Fertility with Kirsten Karchmer: Insights from the Rational Wellness Podcast In this episode of the Rational Wellness Podcast, Dr. Ben Weitz interviews Kirsten Karchmer, a globally recognized fertility expert, acupuncturist, and founder of Conceivable. Kirsten shares her personal journey into the field of fertility, her struggles with MS, and how acupuncture transformed her health. The discussion covers her holistic and technology-based approach to optimizing fertility by addressing root causes through diet, lifestyle, and mindful practices. Key topics include the impacts of stress, sleep, and exercise on fertility, the importance of personalized care, and advancements in technology such as AI predictive tools and non-invasive glucose monitors. Kirsten also highlights the role of epigenetics and provides practical advice for women, especially those over 40, looking to improve their reproductive health naturally. 00:26 Meet Kirsten Karchmer: Fertility Expert 01:28 Kirsten's Journey into Fertility and Acupuncture 06:13 Understanding Functional Medicine and Acupuncture in Fertility 08:42 The Role of Exercise and Energy in Fertility 10:12 Innovative Technology for Health Monitoring 15:57 The Importance of Sleep for Optimal Health 19:38 Nutritional Strategies for Enhancing Fertility 20:41 Addressing Bleeding and Nutrient Needs 21:22 Tailoring Diets for Specific Conditions 21:52 Gut Health and Pregnancy 22:23 Iron and Nutrient Correlation 23:51 Supplements for Fertility 25:53 Managing Stress and Infertility 26:46 Men's Role in Fertility 27:51 Epigenetics and Fertility 30:57 Strategies for Older Women 34:21 Future of Fertility Care 35:54 Key Takeaways and Conclusion ___________________________________________________________________

Kirsten Karchmer is a globally recognized fertility expert, acupunturist, and the CEO and founder of Conceivable. The website is Conceivable.com. Kirsten has spent decades helping women improve their reporductive health, both through her clinical work and through innovative digital solutions. Conceivable uses technology and personalized, science-based programs to optimize fertility by addressing the underlying root causes that impact conception.

Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure. Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111.

Dr. Marc Ryan discusses Managing Hashimoto's Thyroiditis with moderator Dr. Ben Weitz at the Functional Medicine Discussion Group meeting on August 28, 2025.

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Podcast Highlights

Dr. Marc Ryan is a licensed acupuncturist, herbalist, and Functional Medicine practitioner. He's written two books about Hashimoto's thyroiditis, How to Heal Hashimoto's and The Hashimoto's Healing Diet. He teaches at YoSan Acupuncture College, and his practice is devoted to treating patients with Hashimoto's. His website is HashimotosHealing.com.

Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure. Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111.

Dr. Nathan Bryan discusses Increasing Nitric Oxide for Better Health with Dr. Ben Weitz.

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Podcast Highlights

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Dr. Nathan Bryan is an internationally recognized scientist and leading expert in the field of nitric oxide research. Dr. Bryan has spent the last two decades studying the biochemical pathways of nitric oxide and its impact on human health, including cardiovascular health, immune function, and healthy aging. Dr. Bryan has published numerous peer-reviewed papers, books, and he has developed innovative products to restore and optimize nitric oxide production, currently through his N1O1 company available at N1O1.com.

Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure. Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111.

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Jared St. Clair discusses How to Enhance Your Vitality with Proper Nutrition and Lifestyle Changes with Dr. Ben Weitz.

[If you enjoy this podcast, please give us a rating and review on Apple Podcasts, so more people will find The Rational Wellness Podcast. Also check out the video version on my WeitzChiro YouTube page.]

Podcast Highlights

Mastering Nutritional Supplements and Gut Health with Jared St. Clair In this episode of the Rational Wellness Podcast, Dr. Ben White interviews Jared St. Clair, a seasoned herbalist and natural supplement formulator with over 30 years of experience. The discussion focuses on the health status of America, the importance of individuals taking control of their health, and practical strategies for managing conditions like IBS and SIBO. Jared shares insights on the benefits of spore probiotics, digestive enzymes, and a comprehensive approach to detoxification from endocrine disruptors. Additionally, Jared emphasizes the value of personalized supplementation and the importance of understanding product ingredients for optimal health. The episode concludes with advice on maintaining gut health and overall wellness through natural means and consistent education. 00:30 Meet Jared St. Clair: Herbalist and Supplement Expert 01:28 The State of Health in America 02:49 The Importance of Taking Charge of Your Own Health 04:01 Challenges and Successes of Running a Health Food Store 06:29 Discussing Gut Health: IBS and SIBO 10:49 The Gut-Brain Connection and Mental Health 17:31 Strategies for Managing IBS 21:22 The Role of Digestive Enzymes 26:38 Understanding Probiotics: Types and Benefits 31:22 The Role of Lysed Bacteria in Gut Health 31:52 Understanding Postbiotics 32:49 Prebiotics vs. Probiotics vs. Postbiotics 34:16 Favorite Prebiotic Foods 35:40 Evaluating Nutritional Supplements 38:30 Identifying Quality Supplement Brands 45:43 The Impact of Endocrine Disruptors 50:00 Detoxifying Endocrine Disruptors 58:01 Final Thoughts and Contact Information ________________________________________________________

Jared St. Clair is an herbalist and and expert natural supplement formulator with over 30 years of hands-on experience running Vitality Nutrition, a health food store in Utah and the host of the Vitality Radio Podcast. His website is VitalityNutrition.com.

Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure. Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111.