The School of Doza Podcast

Fasting 101: 5 Reasons to Fast for Better Health


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Discover how fasting extends lifespan, lowers insulin and blood sugar, reduces inflammation, regenerates gut cells, and promotes autophagy. Learn the science-backed benefits of fasting and how to implement strategic fasting protocols for metabolic health, cellular repair, and longevity. Nurse Doza breaks down when and how to use fasting as a powerful health tool.

FEATURED PRODUCT

Mitochondriac, featuring resveratrol with quercetin and methylated forms, is designed to support mitochondrial function and mimic the beneficial effects of fasting. Research shows resveratrol activates the same pathways as fasting—AMPK, SIRT1, and PGC-1α—promoting autophagy, mitochondrial biogenesis, and cellular repair. Pairing Mitochondriac with your fasting protocol enhances the metabolic benefits discussed in this episode, making fasting more sustainable and effective for longevity and energy production.
👉 Get Mitochondriac here: https://mswnutrition.com/products/mitochondriac

JOIN THE SCHOOL

Struggling to know how long to fast, what to eat before and after, or how to troubleshoot when a fast doesn't feel right? Inside the School of Doza, you'll join a community of people implementing fasting protocols just like you—and get direct guidance during our Wednesday "Ask Me Anything" sessions that function like group consults. Bring your questions about fasting duration, supplement timing, breaking your fast properly, or interpreting your labs while fasting. Get real-time answers and avoid common fasting mistakes.
Your first 7 days are completely free.
👉 Start your free trial: https://community.schoolofdoza.com/c/start-here

5 KEY TAKEAWAYS

Fasting extends lifespan – Caloric restriction is the only known nutritional intervention proven to extend lifespan and reduce age-related disorders across multiple species by optimizing cellular metabolism.

Fasting lowers insulin and blood sugar – After approximately 10 hours of fasting, stored glycogen is consumed and the body begins breaking down fatty acids, lowering fasting insulin levels and improving insulin sensitivity.
Fasting reduces inflammation – Fasting decreases inflammatory markers including TNF-α, TGF-α, and PDGF, addressing the root cause of conditions like fatty liver, diabetes, autoimmune disorders, and heart disease.
Fasting regenerates gut cells – Caloric restriction increases the number of intestinal stem cells and enhances the regenerative capacity of the injured intestinal epithelium, healing gut damage at the cellular level.
Fasting promotes autophagy and mitochondrial biogenesis – Fasting activates the body's cellular cleanup process (autophagy) and stimulates the creation of new, healthy mitochondria through activation of PGC-1α, AMPK, SIRT1, and NOS pathways.


TIMESTAMPS
00:00 – START
02:00 – What's happening at the School of Doza and weekly Ask Me Anything sessions
04:00 – Fasting extends lifespan through cellular metabolism optimization
08:00 – Fasting lowers insulin and blood sugar after 10 hours
12:00 – How resveratrol mimics fasting and enhances the fasting experience
15:00 – Fasting reduces inflammation across all body systems
19:00 – Fasting regenerates gut cells and heals intestinal damage
22:00 – Fasting promotes autophagy and cleans out toxic cells
26:00 – Mitochondrial biogenesis and the PGC-1α pathway activation
30:00 – Practical fasting protocol guidelines and implementation tips
35:00 – How to pair Mitochondriac with fasting for optimal results
38:00 – Join the School of Doza for fasting support and guidance

RESOURCES

Fasting and cellular metabolism optimization – https://pmc.ncbi.nlm.nih.gov/articles/PMC9042193/

Molecular effects of fasting on cellular metabolism – https://pmc.ncbi.nlm.nih.gov/articles/PMC10413426/
Calorie restriction and lifespan extension – https://www.sciencedirect.com/science/article/pii/S2213671118300523
Calorie restriction reduces fasting insulin levels – https://pmc.ncbi.nlm.nih.gov/articles/PMC8071299/
Glycogen breakdown during starvation – https://www.sciencedirect.com/science/article/pii/S2161831323013443
Resveratrol improves insulin sensitivity through SIRT1/AMPK pathway – https://www.sciencedirect.com/science/article/pii/S0928098725002015
Calorie restriction enhances intestinal regeneration – https://pmc.ncbi.nlm.nih.gov/articles/PMC10069975/
Fasting and autophagy upregulation – https://pubmed.ncbi.nlm.nih.gov/30172870/
Calorie restriction promotes mitochondrial biogenesis – https://www.science.org/doi/10.1126/science.1117728


CONNECT
🔗 Connect with Nurse Doza:
JOIN MY SCHOOL for FREE: https://community.schoolofdoza.com/c/start-here

YouTube: https://www.youtube.com/channel/UCwcKyagDi468WscAOWM5VHA

Instagram: https://www.instagram.com/nursedoza/
Website: http://www.nursedoza.com/
LinkedIn: https://www.linkedin.com/in/jonathan-mendoza-dc-aprn-np-c-0609a038/
TikTok: https://www.tiktok.com/@nursedoza
Twitter: https://twitter.com/nursedoza

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The School of Doza PodcastBy NURSE DOZA

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