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By Dr Rangan Chatterjee: GP & Author
4.8
26622,662 ratings
The podcast currently has 677 episodes available.
The most played episodes among Podcast App listeners.

You might assume that how you’ll age is down to your genes. That your disease risk is out of your hands, sealed by midlife, and something to manage rather than change. But Dr Florence Comite has spent 30 years proving that assumption wrong. And for this conversation, she’s brought the evidence. Florence is a clinician-scientist, Yale and National Institutes of Health-trained endocrinologist, and some might call her a disruptor. Her life’s work has been built on the radical idea that decline is not inevitable, it is detectable. And because it’s detectable, it’s reversible. Her new book, Invincible: Defy Your Genetic Destiny to Live Better Longer, has the core message that our health trajectory is far from fixed. By tuning into our body’s signals, and understanding our physiology, we can make targeted changes to improve how we feel, function and age. In this episode, Florence and I explore why the Western medical model – built around treating disease not creating health – leaves people in the dark when it comes to disease risk. We discuss why the type and frequency of blood tests your doctor currently offers is lacking, as well as what you should ask for (or seek privately) if you want to truly understand your health. Florence talks us through the five blood biomarkers she believes every adult should know about, including one – fasting insulin – that your doctor is highly unlikely to check but that I agree with her is absolutely critical. And she explains why free testosterone is vital for both men and women, how it connects to muscle, memory, bone density, blood sugar and heart health, and why optimising it has transformed some of her patients’ lives. We also sing the praises of continuous glucose monitors. We discuss what they reveal about your individual response to food, why two people can eat the same meal with different results, and how the order in which you eat your meal can change your health. This is a conversation about taking control. It’s about owning your data, your trends – and your future. Florence and I share the belief that our healthcare systems need to move from reactive to proactive. In time, I’m hopeful that will happen. But in the meantime her clinic – and my own Do Health app – are paving an exciting way for you to get ahead of the curve. The Thrive Tour: Transform Your Health and Happiness, a live show: Book Your Tickets https://drchatterjee.com/live Thanks to our sponsors: https://heights.com/livemore https://dohealth.co/livemore https://hellolingo.com/livemore https://airbnb.co.uk/host Show notes https://drchatterjee.com/666 DISCLAIMER: The content in the podcast and on this webpage is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your doctor or qualified healthcare provider. Never disregard professional medical advice or delay in seeking it because of something you have heard on the podcast or on my website. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Most of us assume that memory loss and cognitive decline are just part of getting older. In this episode, a world-leading neurologist says that’s simply not true. That, far from being inevitable, Alzheimer's and other neurodegenerative diseases result from decades of metabolic damage – which we have the power to prevent and even reverse. I’m speaking with Dr David Perlmutter, a board-certified neurologist, six-time New York Times bestselling author, and one of the world's leading experts on brain health. And in this fascinating conversation, we discuss the single biological mechanism that sits at the heart of virtually every neurodegenerative condition, from Alzheimer's and Parkinson's to long Covid and depression, and why understanding it changes everything about how you approach your lifestyle. David’s key insight is that our brain's own immune cells, called microglial cells, have the power to make or break our future brain health. Keep them in their protective state through diet, exercise, and metabolic testing, and we can safeguard our brain for life. Feed them with ultra-processed food and they will shift into a destructive state that drives neuroinflammation. We discuss how, exactly, ultra-processed food damages the brain, why metabolic health is the key to cognitive longevity, and why the diagnosis of Alzheimer's is really the end stage of a process that began decades earlier. The choices you make right now, in your 30s, 40s and 50s, are already shaping the brain you will have in your 70s and beyond. If this all sounds science-heavy, rest assured David approaches it, just as he does in his new book, Brain Defenders, with clarity and plenty of practical takeaway. He outlines the specific blood biomarkers he believes everyone should be tracking, including fasting insulin, homocysteine and uric acid, for a remarkable window into your long-term brain health. We discuss why knowing your numbers is one of the most empowering steps you can take, how to go about getting tested, and how to act on what you find. There is a great deal of fear around dementia, and understandably so. But what I hope you take from this episode is something David emphasises: we needn’t be scared because we have agency. The research is clear that lifestyle choices have a profound impact on your risk, and it is never too early, or too late, to start making them. This is one of the most distinct and important conversations I’ve had about the future of your brain, and I think you will find it incredibly useful, thought-provoking and, above all, hopeful. The Thrive Tour: Transform Your Health and Happiness, a live show: Book Your Tickets https://drchatterjee.com/live Thanks to our sponsors: https://heights.com/livemore https://thesleepreset.com/podcast https://boncharge.com/livemore https://exhalecoffee.com/livemore Show notes https://drchatterjee.com/674 DISCLAIMER: The content in the podcast and on this webpage is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your doctor or qualified healthcare provider. Never disregard professional medical advice or delay in seeking it because of something you have heard on the podcast or on my website. Learn more about your ad choices. Visit podcastchoices.com/adchoices

As we get older, have you ever wondered why the exercise advice we’ve been given doesn’t seem to work as well as it once did? As we move into our 40s and beyond, our physiology changes in ways that can often feel confusing and frustrating. But what if we could harness those changes to feel stronger, healthier and more resilient than ever before? Feel Better Live More Bitesize is my weekly podcast for your mind, body, and heart. Each week I’ll be featuring inspirational stories and practical tips from some of my former guests. Today’s clip is from episode 578 of the podcast with exercise physiologist and nutritional scientist, Dr Stacy Sims. Stacy is dedicated to helping active women – and the people who support them – take back control of their bodies, health and lives through science-based knowledge and practical tools. In this clip, Stacy shares why conventional fitness advice often fails women in midlife, and what many of us may be missing when it comes to improving our health, vitality and resilience as we age. Stacy’s insights remind us that with the right information and support, we can build strength, confidence and better health at any stage of life. Thanks to our sponsor https://heights.com/livemore Show notes and the full podcast are available at drchatterjee.com/578 Support the podcast and enjoy Ad-Free episodes. Try FREE for 7 days on Apple Podcasts https://apple.co/feelbetterlivemore For other podcast platforms go to https://fblm.supercast.com. DISCLAIMER: The content in the podcast and on this webpage is not intended to constitute or be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your doctor or other qualified health care provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have heard on the podcast or on my website. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Why do we sometimes react in ways we don’t mean to? Why does criticism land so heavily when others can brush it off? And why, even when life looks good from the outside, do we feel stuck on the inside? This week’s guest offers a new perspective on all this – and an optimistic way forward. With nearly 10 million followers on Instagram as The Holistic Psychologist, Dr Nicole LePera has helped countless people see their lifelong patterns through a helpful new lens. She joins me to discuss her fantastic book, Reparenting the Inner Child: The New Science of Our Oldest Wounds and How to Heal Them. At the heart of our conversation is an important idea: we don’t see the world as it is, we see it through the state of our nervous system. Nicole highlights the signs that yours may be calling the shots, such as restlessness, numbness, disproportionate reactions and the constant need to be busy. And she explains how those patterns trace back to a part of us shaped long before we had the language for it: our inner child. We explore how childhood adaptations follow us into adulthood, often without us realising, shaping our relationships, our careers, our sensitivity to criticism, and our self-worth. Nicole walks us through some of the parent archetypes from her book. And we discuss the universal choice every child makes between authenticity and attachment (and what this costs us later). Importantly, this is never about blaming, parent or child – acceptance of the past (rather than approval or forgiveness) is how we begin to change. You’ll be fascinated to hear Nicole explain how trauma from generations before us may still be wired into our bodies, but we can break the cycle. We also discuss why conflict in relationships can be healthy, and why healing is a two-step process: becoming aware, and then making different choices. The best part? You’ll come away from this conversation with the tools for change. Nicole talks us through her practical strategies, including the conscious check-in, the three body anchors, bilateral stimulation, and getting to know yourself through simple, mindful moments. Whether you've spent years exploring attachment and inner-child work, or this is your first therapy session, I know you’ll find something here that stays with you. As Nicole says, healing isn’t about reaching an end point. It’s an ongoing process, available to all of us at any moment that we choose to join in. The Thrive Tour: Transform Your Health and Happiness, a live show: Book Your Tickets https://drchatterjee.com/live Thanks to our sponsors: https://dohealth.co/livemore https://thesleepreset.com/podcast https://hellolingo.com/livemore https://airbnb.co.uk/host Show notes https://drchatterjee.com/664 DISCLAIMER: The content in the podcast and on this webpage is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your doctor or qualified healthcare provider. Never disregard professional medical advice or delay in seeking it because of something you have heard on the podcast or on my website. Learn more about your ad choices. Visit podcastchoices.com/adchoices

We’re living in a world that has become extraordinarily skilled at measuring success. But most of us never stop to question which standards really matter to us. Are you chasing success by someone else's definition, without even knowing it? This episode will help you figure that out. My guest is C Thi Nguyen, Associate Professor of Philosophy at the University of Utah and the author of The Score: How to Stop Playing Someone Else's Game, one of the most thought-provoking books I’ve read. This conversation explores where our values really come from, what games and hobbies can teach us about living with freedom, and why so much of what matters most in life resists being measured at all. Thi has developed a fascinating framework for understanding one of the defining problems of modern life: what he calls ‘value capture’. It’s the process by which our own rich, personal values are replaced by simplified external metrics (think followers and likes, salaries, exam grades – even health metrics like your weight or blood pressure score). These metrics can never show the full picture of a human life – but they can end up running it. And once you understand this concept of value capture, you’ll start to notice it everywhere. Thi and I discuss why our culture is so poor at honouring the ‘unmeasurables’. We talk about why joy, love, forgiveness and the quality of our relationships are the substance of a life well lived. Yet they’re systematically undervalued, not because they’re unimportant, but because they’re hard to count. He’s somewhat of an expert on play, whether through sport, board games or hobbies, and we discuss what these activities, often dismissed as trivial, can teach us about meaning and how to live well. Plus, we debate the difference between principles and algorithmic rules – a distinction that might change how you approach your health and your life more broadly. What I love about Thi's thinking is that he’s not telling us to throw out all forms of measurement. He’s more nuanced than that. He is asking us to wake up to the difference between the scorecard we have inherited from the world around us, and the one we would choose for ourselves. He wants us to know that the first step towards genuine fulfilment is simply becoming aware of whose game you have been playing. The Thrive Tour: Transform Your Health and Happiness, a live show: Book Your Tickets https://drchatterjee.com/live Thanks to our sponsors: https://thewayapp.com/livemore https://hellolingo.com/livemore https://exhalecoffee.com/livemore https://drinkag1.com/livemore Show notes https://drchatterjee.com/670 DISCLAIMER: The content in the podcast and on this webpage is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your doctor or qualified healthcare provider. Never disregard professional medical advice or delay in seeking it because of something you have heard on the podcast or on my website. Learn more about your ad choices. Visit podcastchoices.com/adchoices
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