In this episode, Joanne Kennedy discusses a comprehensive case study of a patient with various symptoms like abdominal pain, migraines, and joint pain who was incorrectly suspected of having mold and oxalate problems. The root cause turned out to be gluten intolerance. 

Joanne explains the impact of gluten on the immune system, highlighting how it can cause significant inflammation and histamine issues. She differentiates between celiac disease, wheat allergy, and non-celiac gluten sensitivity, explaining their symptoms, testing methods, and impacts on histamine production. 

Joanne also provides insights into diagnosing these conditions and emphasizes the importance of closely examining patients' diets before attributing symptoms to more complex conditions like mold or oxalate issues.

✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.

📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.

🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.

🎓 Practitioner or student? Apply now for the Histamine & Methylation Online Group Coaching Course starting early 2026!

📆 Work with us 1:1! Book a consultation and take your first step to real healing.

🎤 Have a topic suggestion? Submit it here!

In this episode of the Histamine Well Podcast, Joanne is joined by Amber Romanic, an expert in emotional eating, digestion, and hormonal health.

Amber shares her personal journey overcoming emotional eating and discusses how it impacts gut health and increases histamine levels.

They explore common emotional eating triggers, the role of high cortisol, and the pitfalls of extreme diets like intermittent fasting.

Amber offers practical tips on managing emotional eating, the importance of healing one's relationship with food, and why self-care and setting healthy boundaries are crucial.

Additionally, they touch on the unique challenges women face during different phases of their menstrual cycles and why maintaining a balanced approach is essential for overall well-being.

✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.

📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.

🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.

🎓 Practitioner or student? Apply now for the Histamine & Methylation Online Group Coaching Course starting early 2026!

📆 Work with us 1:1! Book a consultation and take your first step to real healing.

🎤 Have a topic suggestion? Submit it here!

In this episode of the Histamine Well Podcast, Joanne explores the surprising link between high histamine levels and hypoglycemia. 

She details how elevated histamine can disrupt blood sugar regulation through various mechanisms, including overstimulation of insulin production, suppression of glucagon, and cortisol dysregulation. 

Joanne also offers practical advice on managing high histamine and blood sugar levels through diet, stress management, and lifestyle changes. 

Tune in to learn more about identifying and addressing histamine-related blood sugar crashes.

✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.

📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.

🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.

🎓 Practitioner or student? Apply now for the Histamine & Methylation Online Group Coaching Course starting early 2026!

📆 Work with us 1:1! Book a consultation and take your first step to real healing.

🎤 Have a topic suggestion? Submit it here!

In this episode of the Histamine Well Podcast, Joanne is joined by her colleague Melanie Peers to discuss the relationship between small intestinal bacterial overgrowth (SIBO) and histamine intolerance. 

They explore the complexities of SIBO, its causes, symptoms, and its impact on histamine levels in the body. Joanne and Melanie also delve into related issues such as the role of the migrating motor complex, the influence of stress, dietary impacts, and the significance of mold, oxalates, and sulfur in exacerbating histamine symptoms. 

Practical advice on diagnosis, dietary adjustments, and treatment options is provided, making this episode an invaluable resource for both practitioners and individuals seeking to manage their gut health and histamine-related conditions.

✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.

📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.

🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.

🎓 Practitioner or student? Apply now for the Histamine & Methylation Online Group Coaching Course starting early 2026!

📆 Work with us 1:1! Book a consultation and take your first step to real healing.

🎤 Have a topic suggestion? Submit it here!

In this episode of the Histamine Well Podcast, host Joanne Kennedy delves into the significance of digestive enzyme deficiencies in managing histamine intolerance and chronic gut issues like SIBO. 

Joanne explains the critical roles of hydrochloric acid, pancreatic enzymes, and bile acids in maintaining a healthy digestive system, and how their insufficiencies can lead to increased histamine levels and poor gut health. 

The episode covers the symptoms, causes, and solutions for enzyme deficiencies, emphasizing the importance of proper enzyme supplementation. 

Joanne also shares insights into the impacts of stress, diet, and specific medications on enzyme production. This episode is a must-listen for those looking to better understand and manage their digestive health and histamine levels.

✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.

📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.

🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.

🎓 Practitioner or student? Apply now for the Histamine & Methylation Online Group Coaching Course starting early 2026!

📆 Work with us 1:1! Book a consultation and take your first step to real healing.

🎤 Have a topic suggestion? Submit it here!

In this episode of the Histamine Well podcast, Joanne dives into the connection between methylation, detoxification, and gallbladder health. Joined by nutritionist Olivia Haas, they discuss how impaired methylation affects bile flow, leading to gallbladder dysfunction and increased histamines. 

Olivia explains the essential role of the gallbladder in digestion, detoxification, and overall health. They cover early warning signs of gallbladder issues, appropriate testing, and the interplay between estrogen dominance, mold, and oxalate sensitivities. Practical recommendations for dietary and supplement support for gallbladder and liver health, both pre- and post-surgery, are also discussed. 

Olivia also speaks about her specialized programs and memberships designed to assist patients with gallbladder concerns. 

This episode is packed with insights and actionable advice for both practitioners and patients.

✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.

📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.

🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.

🎓 Practitioner or student? Apply now for the Histamine & Methylation Online Group Coaching Course starting early 2026!

📆 Work with us 1:1! Book a consultation and take your first step to real healing.

🎤 Have a topic suggestion? Submit it here!

In this episode of the Histamine Well Podcast, Joanne does something a little different. She shares her step-by-step approach for rapidly lowering your histamine bucket while working toward identifying and treating the root cause. This episode is packed with clinical gems and practical strategies—perfect for both patients and practitioners.

In this episode, you’ll learn:

• Why a low histamine diet is your first line of defense—and where to find a reliable food list
• How DAO enzymes like Seeking Health Histamine Digest help reduce food-based histamine
• The role of mast cell stabilizers like vitamin C and quercetin (e.g. RN Labs QuerceSorb, Thorne Quercetin)
• How Saccharomyces boulardii can support histamine breakdown and gut resilience
• Why SIBO + histamine requires a different approach—including what foods to avoid (spoiler: rice!)
• What to do if you’re constipated and why moving your bowels is essential to reduce histamine
• Thoughts on prokinetics like ginger, Iberogast, and low-dose naltrexone for sluggish gut motility
• What to do when bloating persists despite a perfect diet and supplements
• The hidden impact of oxalates—and how to avoid triggering a painful oxalate dump
• The difference between short-term relief and long-term healing

✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.

📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.

🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.

🎓 Practitioner or student? Apply now for the Histamine & Methylation Online Group Coaching Course starting early 2026!

📆 Work with us 1:1! Book a consultation and take your first step to real healing.

🎤 Have a topic suggestion? Submit it here!

In this episode of the Histamine Well Podcast, Joanne is joined by Naturopath Mariela Gebhardt from Austria to discuss a fascinating and complex case. Initially thought to be related to SIBO, Mariela shares how, despite seeing early improvement in her patient's gut health, she remained in a heightened anxious state and developed an unusual symptom: toe pain.

Mariela identified this as an oxalate issue, which was later confirmed through Organic Acids testing. This discovery prompted Mariela to inquire further about mould exposure, which quickly became clear as a significant factor.

Mariela humbly acknowledges that the mould and oxalate issue should have been identified during the initial consultation, but, due to her lack of training in this area at the time, it wasn’t immediately apparent. However, after mentoring with Joanne and her colleague Melanie Peers, her perspective shifted, and she now approaches these cases with greater insight.

This episode is a must-listen for anyone dealing with chronic histamine issues, as well as practitioners and students interested in more complex cases.

✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.

📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.

🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.

🎓 Practitioner or student? Apply now for the Histamine & Methylation Online Group Coaching Course starting early 2026!

📆 Work with us 1:1! Book a consultation and take your first step to real healing.

🎤 Have a topic suggestion? Submit it here!

In this episode of the Histamine Well Podcast, host Joanne delves into the often-overlooked topic of low homocysteine levels. 

Joanne explains that while high homocysteine is commonly flagged for its cardiovascular risks, low homocysteine is seldom discussed despite its significant implications for health. 

She explores how low homocysteine can indicate sulfur depletion, often linked to issues such as oxalate toxicity and mold illness. 

The episode covers the methylation process, the importance of methionine, and the roles of cysteine, glutathione, and taurine. 

Joanne also discusses the impact of stress, diet, and poor absorption on homocysteine levels and underscores the connection between oxalates and sulfur depletion. 

Whether you are a practitioner or navigating your personal wellness journey, this episode provides actionable insights into understanding and addressing low homocysteine to improve overall health.

✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.

📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.

🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.

🎓 Practitioner or student? Apply now for the Histamine & Methylation Online Group Coaching Course starting early 2026!

📆 Work with us 1:1! Book a consultation and take your first step to real healing.

🎤 Have a topic suggestion? Submit it here!

In this episode of the Histamine Well, Joanne is joined by scientist James Bradshaw to discuss the complexities of methylation and its critical role in genetics, mood, and overall health. 

James shares his extensive background in biochemistry and cellular biology and introduces Mood Sense, the first saliva test for assessing methylation-related mood disruptions. 

They explore the essentials of methylation, its impact on neurotransmitter production, and the difference between over and under methylation. 

The episode also delves into genetic mutations, environmental factors affecting methylation, and practical approaches to managing methylation in clinical practice. 

Listeners gain insights into the role of methylation in various chronic health conditions and how personalized testing can lead to better health outcomes.

✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.

📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively.

🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.

🎓 Practitioner or student? Apply now for the Histamine & Methylation Online Group Coaching Course starting early 2026!

📆 Work with us 1:1! Book a consultation and take your first step to real healing.

🎤 Have a topic suggestion? Submit it here!