ReInvent Healthcare

How Fatty Liver Triggers Insulin Resistance, And What to Do About It


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What if the first signs of metabolic breakdown aren’t in the pancreas or the blood sugar but hidden deep in the liver?

In this episode of ReInvent Healthcare, Dr. Ritamarie takes you inside the metabolic feedback loop few practitioners are trained to detect. Long before glucose rises or A1C shifts, subtle signals in the liver may already be pointing to a much bigger problem. They’re easy to miss, unless you know where to look. Discover the early biochemical whispers of insulin resistance, the hidden drivers of liver fat accumulation, and the lab markers most clinicians overlook. If your clients “look normal” on paper but still struggle, this is the episode you can’t afford to skip.

What’s Inside This Episode?
  • The silent organ shift that can signal metabolic trouble before blood sugar ever changes

  • A hidden fat-making process your body might be running without your consent

  • How a sweet addiction quietly derails liver function and energy production

  • The overlooked lab markers that whisper metabolic distress long before diagnosis

  • A little-known score that could change how you assess “normal” labs

  • Simple but strategic actions that tip the scales from fatty liver to functional health

  • How small shifts in timing and nutrients may unlock powerful liver regeneration

  • Why stable glucose isn’t the full story, and the signal you might be missing

Resources and Links:
  • Download our FREE Metabolic Health Guide here.  
  • Here is a FIB-4 Calculator Tool 
  • FIB-4 = (Age × AST) / (Platelets × √ALT)
  • NAFLD fibrosis score (NFS) = -1.675 + (0.037 × age) + (0.094 × BMI) + (1.13 × hyperglycemia) + (0.99 × AST/ALT ratio) - (0.013 × platelet count) - (0.66 × albumin)
  • Join the Next-Level Health Practitioner Facebook group here for free resources and community support
  • Visit INEMethod.com for advanced health practitioner training and tools to elevate your clinical skills and grow your practice by getting life-changing results. 

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ReInvent HealthcareBy Dr. Ritamarie Loscalzo

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