Research suggests that only 10-30% of our lifespan is determined by our genetics. This means that the vast majority of how we age is directly related to choices we make everyday - how and what we eat, exercise and sleep quality, to name a few. Dr Morgan Levine, Head of the Ageing in Living Systems Lab at Yale University, joins the podcast to share her insights into the cutting-edge developments in the science of aging and longevity.

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Former White House economic advisor Nouriel Roubini joins the podcast for a frightening glimpse into the world’s future. From the worst debt crisis the world has ever seen, to governments pumping out too much money and causing inflation, to borders that are blocked to workers and many shipments of goods, to the rise of a new superpower competition between China and the US, to pandemics and climate change that strike directly at our most populated cities, to the threat to jobs coming from AI, we are facing ten causes of disaster.

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Illness and trauma are defining how we live. 45% of Europeans suffer high blood pressure, and nearly 70% of Americans take at least one prescription drug. The renowned physician, addiction expert and author Gabor Maté joined us live on stage in London to dissect the underlying causes of this malaise - physical and emotional, and connect the dots between our personal suffering and the pressures of modern-day living. Over four decades of clinical experience, Dr Gabor Maté has found that the common definition of 'normal' is false: virtually all disease is actually a natural reflection of life in an abnormal culture, as we grow further and further apart from our true selves.

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The winner of the Nobel Peace Prize, UNESCO World Press Freedom Prize, TIME Person of the Year, and countless further accolades, her work tracking disinformation networks seeded by her own government, spreading lies to its own citizens laced with anger and hate, has landed her in trouble with the most powerful man in the country: President Duterte. Now, hounded by the state, she has multiple arrest warrants against her name. In this episode of the podcast, Maria joins us to tell the story of how democracy dies by a thousand cuts, and how an invisible atom bomb has exploded online that is killing our freedoms.

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Few figures make such a seismic impact on their artistic medium that they transform its reputation from childish pulp entertainment to a vital and exhilarating creative form, capable of exploring the great mysteries of metaphysics, science, and the human spirit – but Alan Moore is one. A modern-day alchemist who transmuted comic books into literary gold, his works not only inspired a later generation of authors who are now household names, from Neil Gaiman to Susanna Clarke, but filmmakers, artists, and storytellers in every medium. He joined us to celebrate Illuminations, his first ever collection of short stories.

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We are often told that the secret to success is hard work, determination, and hours of practice. But in a fast-changing world, what if the really crucial skill is knowing when to stick at something and when to change track and walk away?

Former pro poker player turned decision making expert Annie Duke joins Wharton School economist Katy Milkman to make the under-appreciated case for quitting and also shows you how to get really good at it.

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Arthur C Clarke famously declared that sufficiently advanced technology is indistinguishable from magic. Felix Flicker joins the podcast to make that case, sharing some of the wonders that his own field of condensed matter physics has revealed and offering a glimpse of breathtaking new technologies to come. If you've ever wanted to know about the *real* magical properties of crystals, how to make sense of the quantum realm, or why mirrors reverse you from left to right but not top to bottom, this episode has the answers.

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Join Jools Holland and Mark Cooper as they recount their journey hosting and producing the incredible show, Later... with Jools Holland. Passion for music has never shone brighter: listen to Jools and Mark as they pull back the curtain on classic performances to reveal that the show is just as magical, if even more chaotic, than you imagined.

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Acclaimed author of Empireland and The Boy with the Topknot Sathnam Sanghera takes us on a journey to a fictional cornershop where a story of three generations unfolds. Love, loyalty and betrayal merge within immigrant histories; from breaking Asian stereotypes to discussing the amazing women who inspired his new novel, Sathnam Sanghera tells all in this moving conversation.

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In 2010, Chelsea Manning, working as an intelligence analyst in the United States Army in Iraq, disclosed classified military documents that she had smuggled out via the memory card of her digital camera. The army sentenced her to thirty-five years in prison. The day after her conviction, Manning declared her gender identity as a woman and began to transition. In 2017, President Barack Obama commuted her sentence and she was released. From her struggles as an adolescent, to her decision to send classified documents to WikiLeaks, to her journey ever since, join Manning as she shares her life story.

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