Ivermectin, widely known as an antiparasitic medication, has been investigated for its potential anticancer properties in preclinical studies. Researchers have explored its effects on various cancer cell lines and its possible mechanisms of action.

In this episode, Dr. Moss weighs in on this controversial topic, and let's us know where he feels the scientific research stands, and what the implications of the research mean for the future of cancer treatment.

📚 Cited Studies & Research Links:

1. Award of Nobel Prize to discoverers of ivermectin: Nobel Prize Committee. Nobel Prize in Physiology or Medicine 2015, October 5, 2015. https://www.nobelprize.org/prizes/medicine/2015/press-release/

2. "Among adults with mild COVID-19, a 5-day course of ivermectin, compared with placebo, did not significantly improve the time to resolution of symptoms.” (Ahmed 2021) -- Ahmed S, Karim MM, Ross AG, et al. A five-day course of ivermectin for the treatment of COVID-19 may reduce the duration of illness. Int J Infect Dis. 2021 Feb;103:214-216. doi: 10.1016/j.ijid.2020.11.191. Epub 2020 Dec 2. PMID: 33278625; PMCID: PMC7709596. https://pubmed.ncbi.nlm.nih.gov/33278625/

3. Naggie S, Boulware DR, Lindsell CJ, et al. Effect of Higher-Dose Ivermectin for 6 Days vs Placebo on Time to Sustained Recovery in Outpatients With COVID-19: A Randomized Clinical Trial. JAMA. 2023 Mar 21;329(11):888-897. doi: 10.1001/jama.2023.1650. Erratum in: JAMA. 2024 Jun 4;331(21):1867. doi: 10.1001/jama.2024.8712. Erratum in: JAMA. 2024 Jun 4;331(21):1866-1867. doi: 10.1001/jama.2024.8723. PMID: 36807465; PMCID: PMC9941969. https://pubmed.ncbi.nlm.nih.gov/36807465/

4. ‘Recently, ivermectin has been reported to inhibit the proliferation of several tumor cells by regulating multiple signaling pathways. This suggests that ivermectin may be an anticancer drug with great potential" (Tang 2021). --Tang M, Hu X, Wang Y, et al. Ivermectin, a potential anticancer drug derived from an antiparasitic drug. Pharmacol Res. 2021 Jan;163:105207. doi: 10.1016/j.phrs.2020.105207. Epub 2020 Sep 21. PMID: 32971268; PMCID: PMC7505114. https://pmc.ncbi.nlm.nih.gov/articles/PMC7505114/

5. "Ivermectin preferentially inhibited cancer stem‑like cells (CSC) in breast cancer cells and downregulated the expression of 'stemness' genes" (Dominguez-Gomez 2018). --Dominguez-Gomez G., Chavez-Blanco A., Medina-Franco J.L., et al. Ivermectin as an inhibitor of cancer stem-like cells. Mol Med Rep. 2018;17(2):3397–3403. doi: 10.3892/mmr.2017.8231. https://pubmed.ncbi.nlm.nih.gov/29257278/

How to contact HHS: Assistant Secretary for Health. Phone: 202-690-7694. Email: [email protected]. Postal Address: 200 Independence Avenue, SW. Room 716G. Washington, DC 20201. Website: health.gov. Connect on: X: @HHS_ASH, @HHS_HEALTH. LinkedIn: linkedin.com/company/oash. Media Inquiries: [email protected] and 202-205-0143.

 

Considerations & Limitations

 • Most research is preclinical, meaning studies have been done in cells and animal models, but not yet proven in large human trials.

 • Potential side effects: Though generally safe at prescribed doses, ivermectin is not an FDA-approved cancer treatment, and its effects in cancer patients require further study.

While early studies indicate that ivermectin has potential anticancer properties, more clinical trials are needed to establish its safety and efficacy in humans. Patients interested in alternative treatments should always consult with their healthcare provider before considering off-label uses.

For the full article, with transcript please visit https://themossreport.com

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