LessWrong posts by zvi

“Medical Roundup #3” by Zvi


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This time around, we cover the Hanson/Alexander debates on the value of medicine, and otherwise we mostly have good news.

Technology Advances

Regeneron administers a single shot in a genetically deaf child's ear, and they can hear after a few months, n=2 so far.

Great news: An mRNA vaccine in early human clinical trials reprograms the immune system to attack glioblastoma, the most aggressive and lethal brain tumor. It will now proceed to Phase I. In a saner world, people would be able to try this now.

More great news, we have a cancer vaccine trial in the UK.

And we’re testing personalized mRNA BioNTech canner vaccines too.

US paying Moderna $176 million to develop a pandemic vaccine against bird flu.

We also have this claim that Lorlatinib jumps cancer PFS rates from 8% to 60%.

The GLP-1 Revolution

Early [...]

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Outline:

(00:12) Technology Advances

(01:04) The GLP-1 Revolution

(04:46) Claims About Hansoninan Medicine

(18:36) Pricing

(19:17) Epistemics

(19:39) DEA Worse Than FDA

(21:19) Study Harder

(23:05) FDA Delenda Est

(24:51) Bioethics

(27:28) Covid

(29:21) Demons

(32:48) Genetics

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First published:

July 9th, 2024

Source:

https://www.lesswrong.com/posts/6GhemtgJxF9sSDNrq/medical-roundup-3

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Narrated by TYPE III AUDIO.

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