July 23, 2025

Microbiome, Mycology, and More!

44 minutes

Discover how your gut’s microbial balance affects everything from stress to drug absorption. In this episode of Peptides & Longevity, Afif Ghannoum joins us to unpack the science of the gut microbiome and reveals how imbalances in this ecosystem can disrupt digestion, drug effectiveness, stress response, and immunity.

In this episode of Peptides & Longevity, Afif Ghannoum, a biotechnology entrepreneur, breaks down the emerging science of the total microbiome—including bacteria, fungi, and viruses—and its massive impact on digestion, disease, drug response, and overall health. He shares insights from his father, Dr. Mahmoud Ghannoum, who coined the term ‘mycobiome’ and has led groundbreaking research into how fungi and bacteria form biofilms in the gut, driving inflammation and digestive disorders. Together, they developed BIOHM Health to bring this research to consumers with innovative testing and probiotic solutions.

Afif also reveals surprising truths—like how stress, over-exercise, and restrictive diets can damage the microbiome, and how fungi aren’t inherently bad but vital to gut balance. He explains why prebiotics (dietary fibers that nourish good microbes) may be more important than probiotics alone, and how proper microbial balance affects pain, stress response, immunity, and even medication effectiveness. This is a powerful conversation for anyone who’s struggled with gut issues, chronic symptoms, or confusion about which ‘health rules’ to follow.

Afif Ghannoum

Website: https://www.biohmhealth.com/

LinkedIn: https://www.linkedin.com/in/afifghannoum/

Instagram: https://www.instagram.com/biohmhealth/

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Integrative Peptides

Website: https://integrativepeptides.com/

Facebook: https://www.facebook.com/integrativepeptidesofficial/

Instagram: https://www.instagram.com/integrativepeptides/

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Holtorf Medical Group

Website: https://holtorfmed.com/