Modern Healthspan

Here Dr Seranova talks through her latest paper on the impact of NAD precursors (NR & NMN) on autophagy in human neuron

Dr. Seranova is a serial entrepreneur, holds an MSc in Translational Neuroscience from the University of Sheffield and a PhD in Stem Cell Biology and Autophagy from the University of Birmingham, UK.

🌐Links in this episode

NMN Bio website: https://nmnbio.co.uk/

NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency

https://www.sciencedirect.com/science/article/pii/S2211124723003832

Autophagy promotes cell survival by maintaining NAD levels

https://pubmed.ncbi.nlm.nih.gov/36413951/

Nicotinamide mononucleotide improves the Alzheimer's disease by regulating intestinal microbiota

https://sciencedirect.com/science/article/abs/pii/S0006291X23006538

Nicotinamide mononucleotide inhibits JNK activation to reverse Alzheimer disease

https://pubmed.ncbi.nlm.nih.gov/28330719/

40 Hz frequency studies:

Human study from MIT: https://picower.mit.edu/news/small-studies-40hz-sensory-stimulation-confirm-safety-suggest-alzheimers-benefits

Parkinson's disease study: https://www.mdpi.com/2227-9032/8/2/113

Mouse study: https://www.frontiersin.org/articles/10.3389/fnagi.2023.1129510/full10% Discount on Renue By Science products with code MHS https://renuebyscience.com/ Use SUBMHS for 15% on subscriptions

10% off DoNotAge all products with discount code MHS https://donotage.org/products/

ProHealth 15% of all products Code MODERN: https://www.prohealth.com/

Here Dr Gibala talks how to think about exercise routines and nutrition as well as sharing his own protocol and the current work of his lab

Dr Martin Gibala is a Professor at McMaster University where his research examines the effects of exercise at the molecular to whole body level in both healthy individuals and people with chronic diseases. In addition to basic, mechanistic studies on the regulation of skeletal muscle energy metabolism, his laboratory conducts applied research that examines the impact of physical training and nutrition on human health and performance. He coauthored a book for the general public on the science of time-efficient exercise, The One-Minute Workout: Science Shows a Way to Get Fit That’s Smarter, Faster, Shorter

🌐Links in this episode

World Fitness Level (online VO2max calculator) https://www.worldfitnesslevel.org

Dr Gibala's web site https://martingibala.com/

His page at McMaster University https://experts.mcmaster.ca/display/gibalam

Dr Gibala's Book on Amazon

The One-Minute Workout: Science Shows a Way to Get Fit That's Smarter, Faster, Shorter

https://amzn.to/45VCDNd

10% Discount on Renue By Science products with code MHS https://renuebyscience.com/ Use SUBMHS for 15% on subscriptions

10% off DoNotAge all products with discount code MHS https://donotage.org/products/

ProHealth 15% of all products Code MODERN: https://www.prohealth.com/

Here Dr Gibala talks about what is VO2max, why it is important, how to measure and improve it.

Dr Martin Gibala is a Professor at McMaster University where his research examines the effects of exercise at the molecular to whole body level in both healthy individuals and people with chronic diseases. In addition to basic, mechanistic studies on the regulation of skeletal muscle energy metabolism, his laboratory conducts applied research that examines the impact of physical training and nutrition on human health and performance. He coauthored a book for the general public on the science of time-efficient exercise, The One-Minute Workout: Science Shows a Way to Get Fit That’s Smarter, Faster, Shorter

🌐Links in this episode

World Fitness Level (online VO2max calculator) https://www.worldfitnesslevel.org

Dr Gibala's web site https://martingibala.com/

His page at McMaster University https://experts.mcmaster.ca/display/gibalam

Dr Gibala's Book on Amazon

The One-Minute Workout: Science Shows a Way to Get Fit That's Smarter, Faster, Shorter

https://amzn.to/45VCDNd

10% Discount on Renue By Science products with code MHS https://renuebyscience.com/ Use SUBMHS for 15% on subscriptions

10% off DoNotAge all products with discount code MHS https://donotage.org/products/

ProHealth 15% of all products Code MODERN: https://www.prohealth.com/

Here Dr Gibala introduces interval training and discusses the various styles, and the benefits.

Dr Martin Gibala is a Professor at McMaster University where his research examines the effects of exercise at the molecular to whole body level in both healthy individuals and people with chronic diseases. In addition to basic, mechanistic studies on the regulation of skeletal muscle energy metabolism, his laboratory conducts applied research that examines the impact of physical training and nutrition on human health and performance. He coauthored a book for the general public on the science of time-efficient exercise, The One-Minute Workout: Science Shows a Way to Get Fit That’s Smarter, Faster, Shorter

🌐Links in this episode

World Fitness Level (online VO2max calculator) https://www.worldfitnesslevel.org

Dr Gibala's web site https://martingibala.com/

His page at McMaster University https://experts.mcmaster.ca/display/gibalam

Dr Gibala's Book on Amazon

The One-Minute Workout: Science Shows a Way to Get Fit That's Smarter, Faster, Shorter

https://amzn.to/45VCDNd

10% Discount on Renue By Science products with code MHS https://renuebyscience.com/ Use SUBMHS for 15% on subscriptions

10% off DoNotAge all products with discount code MHS https://donotage.org/products/

ProHealth 15% of all products Code MODERN: https://www.prohealth.com/

Here Dr Patel talks about his topical glutathione treatment Glutaryl and the recent trial that was conducted at McGill University.

Dr. Nayan Patel is an alumnus of the University Of Southern California School Of Pharmacy, where he now serves as adjunct faculty. A pharmacist for over three decades, Patel is an internationally recognized expert, consultant, and lecturer on the Master Antioxidant Glutathione.

Dr. Patel founded Auro Wellness in 2011 to create products to help the body function at an optimal level and reduce the long-term impact of stress on the body. Through his research, Dr. Patel stabilized Glutathione, improved absorption, and increased its effectiveness with the Auro GSH™ Antioxidant Delivery System. He is the author of The Glutathione Revolution: Fight Disease, Slow Aging & Increase Energy, which addresses how powerful and essential Glutathione is to the body’s detoxification system and how to increase the body’s levels naturally.

🌐Links in this episode

Auro Wellness

https://aurowellness.com/

Paper using Auro Wellness Glutaryl

Topical Absorption of Glutathione–Cyclodextrin Nanoparticle Complex in Healthy Human Subjects Improves Immune Response against Mycobacterium avium Infection

https://www.mdpi.com/2076-3921/12/7/1375

Catch us on YouTube: https://www.youtube.com/c/modernhealthspan

10% Discount on Renue By Science products with code MHS https://renuebyscience.com/ Use SUBMHS for 15% on subscriptions

10% off DoNotAge all products with discount code MHS https://donotage.org/products/

ProHealth 15% of all products Code MODERN: https://www.prohealth.com/

Here Dr Patel talks about the changes that happen with glutathione as we age, why it is important and what we can do to restore the levels.

Dr. Nayan Patel is an alumnus of the University Of Southern California School Of Pharmacy, where he now serves as adjunct faculty. A pharmacist for over three decades, Patel is an internationally recognized expert, consultant, and lecturer on the Master Antioxidant Glutathione.

Dr. Patel founded Auro Wellness in 2011 to create products to help the body function at an optimal level and reduce the long-term impact of stress on the body. Through his research, Dr. Patel stabilized Glutathione, improved absorption, and increased its effectiveness with the Auro GSH™ Antioxidant Delivery System. He is the author of The Glutathione Revolution: Fight Disease, Slow Aging & Increase Energy, which addresses how powerful and essential Glutathione is to the body’s detoxification system and how to increase the body’s levels naturally.

🌐Links in this episode

Auro Wellness

https://aurowellness.com/

Paper using Auro Wellness Glutaryl

Topical Absorption of Glutathione–Cyclodextrin Nanoparticle Complex in Healthy Human Subjects Improves Immune Response against Mycobacterium avium Infection

https://www.mdpi.com/2076-3921/12/7/1375

Catch us on YouTube: https://www.youtube.com/c/modernhealthspan

10% Discount on Renue By Science products with code MHS https://renuebyscience.com/ Use SUBMHS for 15% on subscriptions

10% off DoNotAge all products with discount code MHS https://donotage.org/products/

ProHealth 15% of all products Code MODERN: https://www.prohealth.com/

Here Dr Patel talks about glutathione's major two functions in the body, as an antioxidant and a detoxifier. He also discusses measuring our glutathione levels and what would be a good value to aim for.

Dr. Nayan Patel is an alumnus of the University Of Southern California School Of Pharmacy, where he now serves as adjunct faculty. A pharmacist for over three decades, Patel is an internationally recognized expert, consultant, and lecturer on the Master Antioxidant Glutathione.

Dr. Patel founded Auro Wellness in 2011 to create products to help the body function at an optimal level and reduce the long-term impact of stress on the body. Through his research, Dr. Patel stabilized Glutathione, improved absorption, and increased its effectiveness with the Auro GSH™ Antioxidant Delivery System. He is the author of The Glutathione Revolution: Fight Disease, Slow Aging & Increase Energy, which addresses how powerful and essential Glutathione is to the body’s detoxification system and how to increase the body’s levels naturally.

🌐Links in this episode

Auro Wellness

https://aurowellness.com/

Paper using Auro Wellness Glutaryl

Topical Absorption of Glutathione–Cyclodextrin Nanoparticle Complex in Healthy Human Subjects Improves Immune Response against Mycobacterium avium Infection

https://www.mdpi.com/2076-3921/12/7/1375

Catch us on YouTube: https://www.youtube.com/c/modernhealthspan

10% Discount on Renue By Science products with code MHS https://renuebyscience.com/ Use SUBMHS for 15% on subscriptions

10% off DoNotAge all products with discount code MHS https://donotage.org/products/

ProHealth 15% of all products Code MODERN: https://www.prohealth.com/

Here Dr Conlon talks about her personal protocol, that she has decided on as a data driven scientist. We also discuss the next steps for Nuchido as a longevity company.

Dr Nichola Conlon is a molecular biologist specialising in the study of cellular aging. After a career in drug development, she founded Nuchido Laboratories to deliver disruptive innovation in the field of aging, rejuvenation and healthspan.

Dr Conlon has a passion for sharing the latest science and is an accomplished speaker, with a skill for translating advanced science to help educate and support the wider population, encouraging people to age well and achieve their optimal life experience.

🌐Links in this video

Nuchido website https://nuchido.com/

Dr Conlon's Instagram https://www.instagram.com/drnicholaconlon/ (@drnicholaconlon)

Catch us on YouTube: https://www.youtube.com/c/modernhealthspan

10% Discount on Renue By Science products with code MHS https://renuebyscience.com/ Use SUBMHS for 15% on subscriptions

10% off DoNotAge all products with discount code MHS https://donotage.org/products/

ProHealth 15% of all products Code MODERN: https://www.prohealth.com/

Here Dr Conlon talks about the human trial that she sponsored to evaluate the benefits of Time+ on humans.

Dr Nichola Conlon is a molecular biologist specialising in the study of cellular aging. After a career in drug development, she founded Nuchido Laboratories to deliver disruptive innovation in the field of aging, rejuvenation and healthspan.

Dr Conlon has a passion for sharing the latest science and is an accomplished speaker, with a skill for translating advanced science to help educate and support the wider population, encouraging people to age well and achieve their optimal life experience.

🌐Links in this video

Nuchido website https://nuchido.com/

Dr Conlon's Instagram https://www.instagram.com/drnicholaconlon/ (@drnicholaconlon)

Catch us on YouTube: https://www.youtube.com/c/modernhealthspan

10% Discount on Renue By Science products with code MHS https://renuebyscience.com/ Use SUBMHS for 15% on subscriptions

10% off DoNotAge all products with discount code MHS https://donotage.org/products/

ProHealth 15% of all products Code MODERN: https://www.prohealth.com/

Here Dr Conlon talks through all the components of Nuchido Time+ and how they fit into the strategy of restoring NAD by activating the cell's natural mechanisms.

Dr Nichola Conlon is a molecular biologist specialising in the study of cellular aging. After a career in drug development, she founded Nuchido Laboratories to deliver disruptive innovation in the field of aging, rejuvenation and healthspan.

Dr Conlon has a passion for sharing the latest science and is an accomplished speaker, with a skill for translating advanced science to help educate and support the wider population, encouraging people to age well and achieve their optimal life experience.

🌐Links in this video

Nuchido website https://nuchido.com/

Dr Conlon's Instagram https://www.instagram.com/drnicholaconlon/ (@drnicholaconlon)

Catch us on YouTube: https://www.youtube.com/c/modernhealthspan

10% Discount on Renue By Science products with code MHS https://renuebyscience.com/ Use SUBMHS for 15% on subscriptions

10% off DoNotAge all products with discount code MHS https://donotage.org/products/

ProHealth 15% of all products Code MODERN: https://www.prohealth.com/