The Dr. Hyman Show

Psychedelics, Depression, and the Brain: A Breakthrough Framework for Mental Health


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What if the key to healing depression isn’t another pill but a profound shift in consciousness?

On this episode of The Dr. Hyman Show, I talk with Dr. Robin Carhart-Harris, one of the world’s leading psychedelic researchers, about how these compounds unlock plasticity in the brain and offer new hope for people with treatment-resistant mental health challenges.

From trauma recovery to the entropic brain principle, this is a conversation that challenges everything we think we know about the mind. You can watch the full episode on YouTube - https://youtu.be/P0EDsfPwbUQ
In this episode, you’ll learn:
• What happens in the brain during a psychedelic experience and why it matters
• How the right set, setting, and support can shape the outcome of your healing journey
• Why some people improve after one session, while others need a longer path
• The risks of self-medicating and how to explore psychedelics safely
• How emerging tools, including AI, could help personalize treatment and improve recovery
If you’re curious about the healing potential of psychedelics, this is an honest, research-backed conversation worth tuning into.
View Show Notes From This Episode

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The Dr. Hyman ShowBy Dr. Mark Hyman

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