In this episode of The Moss Report, Ben Moss sits down with Dr. Ralph Moss to explore the science of resveratrol, a powerful plant compound found in these two everyday foods. Discover why low doses may be more effective than you think, how synergy between natural compounds supports health, and what the latest research says about cancer stem cells. Listen now and pour yourself a glass of insight.

“Fill up that self-help space with scientifically documented ways to reduce your cancer risk.” – Dr. Ralph W. Moss

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Products mentioned in this podcast:

https://www.drfrankwines.com/

Studies relating red wine:

Chen S, Sun XZ, Kao YC., et al. Suppression of breast cancer cell growth with grape juice. Pharm Biol. 1998;36:53-61.

Chen S, Yi Y, Xia T, et al. The influences of red wine in phenotypes of human cancer cells. Gene. 2019 Jun 20;702:194-204. doi: 10.1016/j.gene.2018.10.049. Epub 2018 Oct 23. PMID: 30366081; PMCID: PMC6478559. (“The results reveal that the red wine also inhibits colony formation of human breast cancer and esophageal carcinoma cells.”)

Eng ET, Williams D, Mandava U, et al. Suppression of aromatase (estrogen synthetase) by red wine phytochemicals. Breast Cancer Res Treat. 2001 May;67(2):133-46. doi: 10.1023/a:1010641102147. PMID: 11519862.

Eng ET, Ye J, Williams D, et al. Suppression of estrogen biosynthesis by procyanidin dimers in red wine and grape seeds. Cancer Res. 2003 Dec 1;63(23):8516-22. PMID: 14679019.

LeBlanc, Mark Rene. Cultivar, Juice Extraction, Ultra Violet Irradiation and Storage Influence the Stilbene Content of Muscadine Grapes (Vitis Rotundifolia Michx.). A Dissertation Submitted to the Graduate Faculty of the Louisiana State University, 2005.

Lee H, Gourley L, Duffy SW, et al. Dietary effects on breast-cancer risk in Singapore. Lancet. 1991;337:1197–1200.

Roan, Shari. Light drinking linked to increased breast cancer risk. Los Angeles Times, Nov. 1, 2011.

Roy H, Lundy S. Resveratrol, Pennington Nutrition Series, 2005 No. 7

Siemann EH and Creasy LL. Concentration of the Phytoalexin Resveratrol in Wine. Am. J. Enol. Vitic. 1992;43:9-52 

Stervbo U, Vang O, Bonnesen C. A review of the content of the putative chemopreventive phytoalexin resveratrol in red wine". Food Chemistry. 2007;101:44957.

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Peanuts and Cancer

Aune D, Keum N, Giovannucci E, et al Nut consumption and risk of cardiovascular disease, total cancer, all-cause and cause-specific mortality: a systematic review and dose-response meta-analysis of prospective studies. BMC Med. 2016 Dec 5;14(1):207. doi: 10.1186/s12916-016-0730-3. PMID: 27916000; PMCID: PMC5137221.

Balakrishna R, Bjørnerud T, Bemanian M, et al. Consumption of Nuts and Seeds and Health Outcomes Including Cardiovascular Disease, Diabetes and Metabolic Disease, Cancer, and Mortality: An Umbrella Review. Adv Nutr. 2022 Dec 22;13(6):2136-2148. doi: 10.1093/advances/nmac077. PMID: 36041171; PMCID: PMC9776667.

Bolling BW, Aune D, Noh H, et al. Dried Fruits, Nuts, and Cancer Risk and Survival: A Review of the Evidence and Future Research Directions. Nutrients. 2023 Mar 16;15(6):1443. doi: 10.3390/nu15061443. PMID: 36986173; PMCID: PMC10051070.

Jantip PA, Singh CK, Klu YAK, Ahmad N, Bolling BW. Peanut skin polyphenols inhibit proliferation of leukemia cells in vitro, and its A-type procyanidins selectively pass through a Caco-2 intestinal barrier. J Food Sci. 2025 Feb;90(2):e70018. doi: 10.1111/1750-3841.70018. PMID: 39949260; PMCID: PMC11826137.

Nguyen SM, Tran TDC, Tran TM, Wang C, Wu J, Cai Q, Ye F, Shu XO. Influence of Peanut Consumption on the Gut Microbiome: A Randomized Clinical Trial. Nutrients. 2024 Sep 30;16(19):3313. doi: 10.3390/nu16193313. PMID: 39408280; PMCID: PMC11478729.

Yadav A, Gupta P, Gupta P, et al. Aflatoxin exposure is associated with an increased risk of gallbladder cancer. Int J Cancer. 2025 Jan 15;156(2):322-330. doi: 10.1002/ijc.35171. Epub 2024 Sep 6. PMID: 39239866.