Summary of the Podcast:
Regan Archibald interviews Dr. Tim Nelson, the CEO of HeartWorks and a leading expert in stem cell research. They discuss the evolution of stem cell technology over two decades, highlighting the paradigm shift from human embryonic stem cells to induced pluripotent stem cells. Dr. Nelson emphasizes the ethical and scientific challenges associated with embryonic stem cells and the groundbreaking potential of induced pluripotent stem cells.
The conversation delves into Dr. Nelson's experience at the Mayo Clinic and the significant advancements in stem cell research, particularly in the field of regenerating heart tissue. He shares insights into the reprogramming of skin cells into induced pluripotent stem cells and the transformative effects on the aging process, including age reversal at the cellular level.
Dr. Nelson explains the current focus on using stem cells to rebuild hearts, especially for patients with congenital heart defects. The podcast explores the FDA-approved clinical trials for this groundbreaking technology, allowing the regeneration of heart muscle from patients' own cells.
Looking ahead, Dr. Nelson envisions the near-term application of stem cell technology for patients with pump failure, emphasizing the potential to surgically rescue and remuscularize hearts. In the long term, the discussion turns to the broader implications for longevity, identifying genetic factors affecting heart health, and addressing gaps in the body's natural ability to regenerate tissues.
Overall, the podcast provides a comprehensive overview of the evolution, current applications, and future possibilities of stem cell technology in the field of regenerative medicine, with a focus on cardiac health and longevity.
Learn more about Dr. Nelson's mission here: https://heartworks.iandpdev.com