The Obesity Guide with Matthea Rentea MD

The 3 Stages of GLP-1s: What to Expect and How to Adjust


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If you’re on a GLP-1 medication, you’ve probably noticed your appetite, cravings, or progress shifting over time, and it can feel confusing or even a little scary. Most people assume they’re supposed to feel the same way the entire journey, so when hunger returns, appetite increases, or cravings pop up again, the panic sets in. 

Add in the highlight reel of social media (where everything looks effortless and perfectly controlled), and it’s no wonder so many people start to feel like they’re “failing” or doing something wrong.

In this episode, I break down the three distinct phases nearly everyone on GLP-1s experiences and how to navigate each stage with confidence instead of fear. You'll learn the nutrition, lifestyle, and mindset strategies that make the biggest difference at each phase, so you can stop panicking and start problem-solving.

References

The 3 Phases of a GLP-1 TikTok Video 


The Top 5 Mistakes That People Make on a GLP-1 Mini Course

Clinician Social Accelerator Course

The Obesity Guide: Full Podcast Library


Audio Stamps

00:30 – Dr. Rentea's viral TikTok on the three phases of GLP-1s went viral as people realized their experience isn't unique. 

03:52 – Inside the April 2026 "Beyond the Scale" retreat: body image work, genetics, women's health, and hands-on nutrition workshops.

08:58 – Overview of the three distinct phases on GLP-1 medications and what to expect in each one.

09:20 – Phase One: Prioritizing nutrient-dense foods, not losing too quickly, and avoiding extreme suppression.

13:15 – Phase Two: Adding volume-based eating back while maintaining protein, fiber, and fats.

16:02 – Phase Three: Managing cravings with food ordering, balanced macros, sleep, and stress management.

22:14 – Quick summary of all three phases and why finding an experienced medical team makes all the difference.

All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast.

If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com

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The Obesity Guide with Matthea Rentea MDBy Matthea Rentea MD

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