Dr. Gillett and James O'Hara discuss an article on Bigorexia. 

Article:

► https://www.huffpost.com/entry/bigorexia-parents-boys_l_6786dc1ee4b0a673540f92d2

 

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#bodybuilding #mentalhealth #podcast 

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Dr. Gillett and James O'Hara discuss a new study on Cagrisema. 

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Code: Sarcasm12 

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#weightloss #peptides #health

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The guys discuss many things including the HCG diet with The Protein Bros

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► https://www.youtube.com/@UCUQOvzxP8I_Ku0vpEIqDYpg 

► https://www.instagram.com/proteinbrospodcast/

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#peptides #diet #protein

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The guys do a protein bar taste test with The Protein Bros

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Dr. Gillett and James O'Hara break down BPC-157. 

Studies/References:

► https://annular.com/collections/peptides?srsltid=AfmBOoo96nXrlsyErMHDvsbg0_pdIxRIgBLe2GtiMZ5JwW2I-e90VlEN

► https://www.metabolicelite.co/shop/

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#bpc

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Dr. Gillett and James O'Hara rank their favorite GLP-1s based on efficacy and risk.

Studies/References:

► https://pmc.ncbi.nlm.nih.gov/articles/PMC12318778/

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Dr. Gillett and James O'Hara go over the new food pyramid. 

00:00 Intro

01:02 Protein is a welcomed change, but similarities to the old pyramid raise concerns.

05:39 Public perception of saturated fat is still mixed.

07:41 Sodium recommendations.

11:10 Added sugar intake.

14:41 Protein and fiber. 

Studies/References:

► https://cdn.realfood.gov/DGA.pdf

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Code: Sarcasm12

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#food #fda #government #health #meat #protein

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Dr. Gillett and James O'Hara discuss prenuvo mri scans and the recent malpractice case.   

Studies/References:

► https://radiologybusiness.com/topics/healthcare-management/legal-news/whole-body-mri-provider-prenuvo-loses-bid-limit-damages-high-profile-malpractice-case

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#health #news #darkside #stroke

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James O'Hara sits down with Dr Dan Bristow (OB-GYN) to talk about hormones

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►Compiled Source List

Systematic and Narrative Reviews

1. Gut microbial β‑glucuronidase: a vital regulator in female estrogen metabolism and gynecologic cancers

PMCID: PMC10416750

• Year: 2023

• Journal: International Journal of Molecular Sciences

• Summary: Reviews role of β-glucuronidase in estrogen metabolism, breast cancer, endometriosis.

2. A New Paradigm in Gut Microbiota & Breast Cancer: β‑Glucuronidase as Therapeutic Target

DOI: 10.3390/pathogens12091086

• Year: 2023

• Journal: Pathogens

• Summary: Emerging model proposing gmGUS as a direct target in estrogen-driven breast cancer.

3. Gut and oral microbiota in gynecologic cancers: mechanisms and therapeutic value

DOI: 10.1038/s41522-024-00577-7

• Year: 2024

• Journal: npj Biofilms and Microbiomes

• Summary: Systematic review on microbiota’s role in ovarian, cervical, and breast cancers.

Human Clinical or Case-Control Studies

4. Assessment of gut microbial β‑glucuronidase and β‑glucosidase activity in women with PCOS

PMCID: PMC10366212

• Year: 2023

• Journal: Scientific Reports

• Summary: Found significantly higher β-glucuronidase activity in PCOS patients.

5. Gut microbiota and ovarian diseases: a new therapeutic perspective

DOI: 10.1186/s13048-025-01684-5

• Year: 2025

• Journal: Journal of Ovarian Research

• Summary: Review covering PCOS, POI, and tumors—describes estrogen recycling via gut microbiota.

Mechanistic, In Vitro, and Animal Studies

6. In vitro analysis of gut microbial β‑glucuronidases and estrogen deconjugation

DOI: 10.1016/j.jbc.2020.105542

• Year: 2020

• Journal: Journal of Biological Chemistry

• Summary: Characterized 35 GUS enzymes that reactivate estrogen glucuronides.

7. Impact of intestinal flora on ovarian function and disease pathogenesis

Full text: e-century.us

• Year: 2024

• Journal: American Journal of Translational Research

• Summary: Animal studies showing how β-G-producing gut bacteria drive ovarian dysfunction.

8. The role of gut microbiota in endometriosis: current insights

DOI: 10.3389/fmicb.2024.1363455

• Year: 2024

• Journal: Frontiers in Microbiology

• Summary: Mechanistic review linking β-G-producing bacteria to lesion development and inflammation in endometriosis.

#female #femalehealth #hormones #testosterone

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Dr. Gillett and James O'Hara sit down with Andy Kushner (physical therapist) to talk about pec tears.  

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Follow Kyle Gillett, MD

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#podcast #injury #health #interview

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