The Joe Cohen Show

In this episode, Joe discusses skin health, anti-aging strategies, and the science behind skincare with biohacker and beauty industry leader Amitay Eshel, CEO of Young Goose. 

Amitay shares his expertise on improving skin health through a combination of internal health, high-quality skincare products, and biohacking techniques. 

The conversation covers topics such as the efficacy of various skincare ingredients, the impact of sun exposure, and innovative approaches to anti-aging. 

Amitay also delves into the science of skin renewal, the role of vitamins and metabolites in skin health, and offers practical advice on creating an effective skincare regimen tailored to individual needs and skin types.

- Use code “SELFDECODE” for 10% off younggoose.com

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/ 

In this episode, we uncover the significance of the CLOCK and PER2 genes, pivotal players in regulating your body's circadian rhythm. Learn how these genes influence your sleep patterns, alertness levels, and even your predisposition to certain health conditions.

Discover how variants in the CLOCK gene can impact your circadian rhythm, sleep duration, and daily activity patterns. 

Explore the associations between genetic variations in the PER2 gene and your tendency to be an early riser or a night owl, as well as its influence on sleep disorders and mood.

If you're interested in learning more about how your DNA and genetics affect your health, you can:

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/ 

In this episode, Joe brings on Dr. Ben Lynch - renowned geneticist and author of Dirty Genes - to unreavel the science of methylation, MTHFR, folates, and homocysteine.

Dr. Lynch intricately unpacks the complexities of methylation pathways, shedding light on how genetic variations can impact these crucial processes. 

Joe and Ben then delve into the specifics of homocysteine metabolism and the role of B vitamins in maintaining optimal levels.

They provide invaluable insights into personalized supplements tailored to address individual genetic predispositions and health needs.

Explore the latest advancements in methylation and homocysteine management, and discover actionable strategies for promoting longevity and optimal well being.

- Visit @drbenlynch on Instagram

- Use code "SelfDecode10" to get 10% off seekinghealth.com 

If you're interested in learning more about how your DNA and genetics affect your health, you can:

- Check out SelfDecode: ⁠https://selfdecode.com/⁠

- Join Joe’s online community: ⁠https://thejoecohenshow.com/⁠ 

Timestamps:

(0:00) - Intro

(1:09) - State of the genetics industry

(20:07) - MTHFR and methylation

(1:04:59) - Is overmethylating real?

(1:12:06) - Riboflavin and other B vitamins

(1:18:06) - How many supplements does Ben take a day?

(1:31:54) - Epigenetics and other alternative tests

In this episode of SNPit, we delve into the fascinating world of the FOXO3 gene, a genetic guardian that holds the key to a longer life. 

But here's the twist: did you know that certain variants of this gene could impact your lifespan more than smoking a pack of cigarettes every day for 25 years? 

We uncover the research behind this startling revelation and discuss the implications for our health and well-being. 

Plus, we reveal actionable steps you can take to optimize your FOXO3 gene for better longevity. 

If you're interested in learning more about how your DNA and genetics affect your health, you can:

- Check out SelfDecode: ⁠https://selfdecode.com/⁠

- Join Joe’s online community: ⁠https://thejoecohenshow.com/⁠ 

Joe delves deep into the world of biohacking alongside esteemed naturopath Michael Smith. 

Drawing on two decades of expertise, Michael shares invaluable insights into optimizing health, particularly focusing on gut health and the microbiome. 

From his personal journey to professional practice, Michael discusses the latest advancements in gut health research, tackling issues such as fatigue, autoimmune conditions, and more.

Michael shares some practical strategies for enhancing gut health and addressing chronic conditions.

Join Joe and Michael as they explore the pivotal role of lifestyle changes, targeted supplements, and personalized DNA data in achieving optimal well-being.

- Learn more about Michael’s practice at https://www.planetnaturopath.com/

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/ 

Timestamps:

(0:00) - Michael Smith

(01:51) - Michael's process with patients

(10:34) - Important health data points

(19:21) - Looking at gut health

(27:35) - Food sensitivities and gut health

(32:56) - Other alternative markers and tests

(38:44) - Going through test results

Today, we're excited to bring you the cream of the crop – the top 6 health advice of Season 5 - that have not only resonated most with our listeners but have the power to transform your approach to health and wellness.

These highlights encapsulate the essence of what it means to live well in today's world. Each clip has been handpicked for its impact, insight, and potential to inspire positive change in your life. Whether you're a long-time listener or just joining us, this episode is your gateway to the best health advice we've uncovered in Season 5.

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/ 

Timestamps:

(0:00) - Intro

(0:16) - Oz Garcia

(8:31) - Methylation

(17:44) - Michael Lustgarten

(24:26) - Optimal Lab Levels

(29:37) - Matt Kaeberlein

(46:34) - Immune System

Get an in-depth overview of the components of the immune system, learn how to identify when they're compromised, and get insights on how to support them to prepare your body for illness. 

Joe discusses the importance of focusing on immune support before illness occurs, diving deep into the roles of mitochondria, extracellular matrix, and inflammation, and how their strengths affects the immune system - sharing key supplements that help optimize each component!

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/ 

In this episode, we focus on the FTO gene's pivotal role in fat metabolism, appetite, and weight management. 

Get an in-depth analysis of how the FTO gene not only influences body weight and obesity risk but also regulates appetite and fat metabolism, alongside managing emotional eating and hunger levels. 

We discuss the gene's connection to weight-related challenges, including its effects on insulin resistance, blood sugar levels, and energy expenditure. 

By understanding one’s genetic predispositions, individuals can adopt personalized approaches to diet, lifestyle, and supplementation, turning genetic insights into actionable plans for improving fat metabolism and achieving weight management goals. 

If you're interested in learning more about how your DNA and genetics affect your health, you can:

- Check out SelfDecode: ⁠https://selfdecode.com/⁠

- Join Joe’s online community: ⁠https://thejoecohenshow.com/⁠ 

In this episode, Dr. Matt Kaeberlein, CEO of OptiSpan and co-director of the Dog Aging Project, and Joe explore the fascinating realm of rapamycin and its implications for longevity and healthspan.

Dr. Kaeberlein delves into the biological mechanisms underlying rapamycin's effects, the best way to take it, and its impact on immune system processes.

Gain insights from Dr. Kaeberlein's research on the mTor mechanism and rapamycin, uncovering their promising potential in extending healthspan and enhancing lifespan.

Finally, Matt and Joe discuss aging clocks, biomarkers, and microbiome tests, evaluating their significance in the context of aging research and longevity enhancement.

- Visit https://www.optispan.life/

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/ 

Timestamps:

(0:00) - Intro

(02:24) - Rapamycin overview

(22:04) - How Matt uses Rapamycin

(33:24) - Biomarkers affected by rapamycin

(37:33) -  Microbiome and aging clocks

(01:04:07) - How much can you maximize life span

Dive into the world of lab testing and unlock the secrets to optimal health.

In this episode, Joe sheds light on the crucial role lab tests play in understanding our health, cautioning against the limitations of standard tests often offered by conventional medicine. 

Delve deep into the realm of comprehensive testing as Joe shares his insights on a variety of essential lab markers, including Complete Metabolic Panel, Complete Blood Count, Thyroid Panel, and Amino Acid Panel, among others. 

Learn why these tests are vital for gaining a holistic view of your well-being.

Discover common misconceptions surrounding lab tests and explore the benefits of leveraging advanced tools like SelfDecode for managing and analyzing your lab results effectively. 

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/ 

Timestamps:

(0:00) - Intro

(0:40) - Mistakes people make when taking lab tests

(5:06) - Important lab tests

(11:34) - My journey with labs

(14:55) - The lab tests I take every quarter