Peptides and Longevity: Redefining Aging and Transforming Health with Dr. Kent Holtorf

The Longevity Shortcut: How Mitochondrial Peptides Reverse Aging


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In this episode of the Peptides & Longevity Podcast, Dr. George Rice joins us to explore the vital role of mitochondrial health in energy, longevity, and chronic disease. We also dive into how mitochondrial peptides can help reverse aging-related dysfunctions and ignite optimal health from the cellular level up.


In this episode of the Peptides & Longevity Podcast, Dr. George Rice joins us to explain why the key to reversing chronic disease and aging might be hidden inside our mitochondria. These tiny energy factories do far more than just fuel our cells—they regulate calcium, cell survival, inflammation, insulin sensitivity, and more. As we age, mitochondrial function declines, leading to everything from fatigue to neurodegeneration. Dr. Rice emphasizes that rather than viewing this dysfunction as inevitable, we now have powerful tools to support and restore mitochondrial health, particularly through mitochondrial-derived peptides like MOTS-c.

Dr. Rice also discusses the science and clinical experience behind using MOTS-c and other mitochondrial-targeted peptides to treat patients with conditions like heart failure, autoimmune issues, chronic fatigue, and metabolic disorders. He also unpacks the importance of personalized medicine, epigenetic testing, and functional diagnostics to tailor interventions to the individual. Whether it’s hormone balancing, strategic peptide use, or nutrition that fuels mitochondrial resilience, this episode gives you an inspiring, data-backed approach to not just living longer, but living better.


Dr. George Rice is a board-certified physician specializing in functional and precision performance medicine, with a mission to help patients not just survive but thrive.. Dr. Rice holds multiple certifications, including from the Institute for Functional Medicine, the Academy of Preventative and Innovative Medicine, and the Age Management Medical Group. Known for his dynamic, patient-centered approach, he combines advanced diagnostic testing with cutting-edge therapies like peptide treatments, hormone optimization, and epigenetic coaching to help clients reach peak physical performance, youthful vitality, and lasting longevity. His work is guided by the belief that optimal health is achievable at any age—and that the mitochondria are the key to unlocking it.

Dr. George Rice

Website: https://ileraprecisionwellness.com/dr-george-rice

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Integrative Peptides

Website: https://integrativepeptides.com/

Facebook: https://www.facebook.com/integrativepeptidesofficial/

Instagram: https://www.instagram.com/integrativepeptides/

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Holtorf Medical Group

Website: https://holtorfmed.com/

Facebook: https://www.facebook.com/holtorfmed/

Instagram: https://www.instagram.com/holtorfmedicalgroup/

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Kent Holtorf, MD

YouTube: https://www.youtube.com/channel/UC0S6Kaa1V9-dfo2sPyZPT6A

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Produced by DrTalks  https://drtalks.com/podcast-service/

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Peptides and Longevity: Redefining Aging and Transforming Health with Dr. Kent HoltorfBy Kent Holtorf, MD

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